Mitochondrial Disorders: Biochemical and Molecular Analysis
Due to the complexity of the mitochondrial system and the myriad genes involved in their function, the clinical manifestations of mitochondrial diseases are remarkably variable and heterogeneous. The laboratory and clinical methodologies used to evaluate dysfunction may vary widely, and thusly a sys...
Gespeichert in:
| Weitere Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2012
|
| Schriftenreihe: | Methods in Molecular Biology, Methods and Protocols
837 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 URL des Erstveröffentlichers |
| Zusammenfassung: | Due to the complexity of the mitochondrial system and the myriad genes involved in their function, the clinical manifestations of mitochondrial diseases are remarkably variable and heterogeneous. The laboratory and clinical methodologies used to evaluate dysfunction may vary widely, and thusly a systematic presentation of the numerous protocols that are applied to the assessment of these clinically and genetically heterogeneous disorders has proven to be essential. Mitochondrial Disorders: Biochemical and Molecular Analysis strives to fill this need with a collection of key protocols provided by leading experts in the field. Beginning with overviews of complexity of mitochondrial and nuclear genome disorders, the book continues with a section devoted to current biochemical protocols and a part focused on the DNA-based approaches used to identify molecular defects. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Detailed and authoritative, Mitochondrial Disorders: Biochemical and Molecular Analysis serves as a vital guide to researchers seeking to understand this incredibly complicated type of breakdown in cellular biology |
| Beschreibung: | 1 Online-Ressource (XI, 352 p. 56 illus., 14 illus. in color) |
| ISBN: | 9781617795046 |
| DOI: | 10.1007/978-1-61779-504-6 |
Internformat
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| 520 | |a Due to the complexity of the mitochondrial system and the myriad genes involved in their function, the clinical manifestations of mitochondrial diseases are remarkably variable and heterogeneous. The laboratory and clinical methodologies used to evaluate dysfunction may vary widely, and thusly a systematic presentation of the numerous protocols that are applied to the assessment of these clinically and genetically heterogeneous disorders has proven to be essential. Mitochondrial Disorders: Biochemical and Molecular Analysis strives to fill this need with a collection of key protocols provided by leading experts in the field. Beginning with overviews of complexity of mitochondrial and nuclear genome disorders, the book continues with a section devoted to current biochemical protocols and a part focused on the DNA-based approaches used to identify molecular defects. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Detailed and authoritative, Mitochondrial Disorders: Biochemical and Molecular Analysis serves as a vital guide to researchers seeking to understand this incredibly complicated type of breakdown in cellular biology | ||
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Datensatz im Suchindex
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| dewey-full | 571.6 611.01815 |
| dewey-hundreds | 500 - Natural sciences and mathematics 600 - Technology (Applied sciences) |
| dewey-ones | 571 - Physiology & related subjects 611 - Human anatomy, cytology, histology |
| dewey-raw | 571.6 611.01815 |
| dewey-search | 571.6 611.01815 |
| dewey-sort | 3571.6 |
| dewey-tens | 570 - Biology 610 - Medicine and health |
| discipline | Biologie Medizin |
| doi_str_mv | 10.1007/978-1-61779-504-6 |
| format | Electronic eBook |
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| spelling | Mitochondrial Disorders Biochemical and Molecular Analysis edited by Lee-Jun C. Wong, Ph.D. Totowa, NJ Humana Press 2012 1 Online-Ressource (XI, 352 p. 56 illus., 14 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology, Methods and Protocols 837 Due to the complexity of the mitochondrial system and the myriad genes involved in their function, the clinical manifestations of mitochondrial diseases are remarkably variable and heterogeneous. The laboratory and clinical methodologies used to evaluate dysfunction may vary widely, and thusly a systematic presentation of the numerous protocols that are applied to the assessment of these clinically and genetically heterogeneous disorders has proven to be essential. Mitochondrial Disorders: Biochemical and Molecular Analysis strives to fill this need with a collection of key protocols provided by leading experts in the field. Beginning with overviews of complexity of mitochondrial and nuclear genome disorders, the book continues with a section devoted to current biochemical protocols and a part focused on the DNA-based approaches used to identify molecular defects. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Detailed and authoritative, Mitochondrial Disorders: Biochemical and Molecular Analysis serves as a vital guide to researchers seeking to understand this incredibly complicated type of breakdown in cellular biology Life Sciences Cell Biology Laboratory Medicine Life sciences Laboratory medicine Cell biology Labortechnik (DE-588)4123602-6 gnd rswk-swf Mitochondriopathie (DE-588)4280150-3 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Mitochondriopathie (DE-588)4280150-3 s Labortechnik (DE-588)4123602-6 s b DE-604 Wong, Ph.D., Lee-Jun C. edt Erscheint auch als Druck-Ausgabe 9781617795039 https://doi.org/10.1007/978-1-61779-504-6 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Mitochondrial Disorders Biochemical and Molecular Analysis Life Sciences Cell Biology Laboratory Medicine Life sciences Laboratory medicine Cell biology Labortechnik (DE-588)4123602-6 gnd Mitochondriopathie (DE-588)4280150-3 gnd |
| subject_GND | (DE-588)4123602-6 (DE-588)4280150-3 (DE-588)4143413-4 |
| title | Mitochondrial Disorders Biochemical and Molecular Analysis |
| title_auth | Mitochondrial Disorders Biochemical and Molecular Analysis |
| title_exact_search | Mitochondrial Disorders Biochemical and Molecular Analysis |
| title_full | Mitochondrial Disorders Biochemical and Molecular Analysis edited by Lee-Jun C. Wong, Ph.D. |
| title_fullStr | Mitochondrial Disorders Biochemical and Molecular Analysis edited by Lee-Jun C. Wong, Ph.D. |
| title_full_unstemmed | Mitochondrial Disorders Biochemical and Molecular Analysis edited by Lee-Jun C. Wong, Ph.D. |
| title_short | Mitochondrial Disorders |
| title_sort | mitochondrial disorders biochemical and molecular analysis |
| title_sub | Biochemical and Molecular Analysis |
| topic | Life Sciences Cell Biology Laboratory Medicine Life sciences Laboratory medicine Cell biology Labortechnik (DE-588)4123602-6 gnd Mitochondriopathie (DE-588)4280150-3 gnd |
| topic_facet | Life Sciences Cell Biology Laboratory Medicine Life sciences Laboratory medicine Cell biology Labortechnik Mitochondriopathie Aufsatzsammlung |
| url | https://doi.org/10.1007/978-1-61779-504-6 |
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