Systems Metabolic Engineering: Methods and Protocols
With the ultimate goal of systematically and robustly defining the specific perturbations necessary to alter a cellular phenotype, systems metabolic engineering has the potential to lead to a complete cell model capable of simulating cell and metabolic function as well as predicting phenotypic respo...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2013
|
| Schriftenreihe: | Methods in Molecular Biology, Methods and Protocols
985 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 URL des Erstveröffentlichers |
| Zusammenfassung: | With the ultimate goal of systematically and robustly defining the specific perturbations necessary to alter a cellular phenotype, systems metabolic engineering has the potential to lead to a complete cell model capable of simulating cell and metabolic function as well as predicting phenotypic response to changes in media, gene knockouts/overexpressions, or the incorporation of heterologous pathways. In Systems Metabolic Engineering: Methods and Protocols, experts in the field describe the methodologies and approaches in the area of systems metabolic engineering and provide a step-by-step guide for their implementation. Four major tenants of this approach are addressed, including modeling and simulation, multiplexed genome engineering, ‘omics technologies, and large data-set incorporation and synthesis, all elucidated through the use of model host organisms. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions on their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Systems Metabolic Engineering: Methods and Protocols serves as an ideal guide for metabolic engineers, molecular biologists, and microbiologists aiming to implement the most recent approaches available in the field |
| Beschreibung: | 1 Online-Ressource (XII, 474 p. 61 illus., 47 illus. in color) |
| ISBN: | 9781627032995 |
| DOI: | 10.1007/978-1-62703-299-5 |
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Datensatz im Suchindex
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| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 660 - Chemical engineering |
| dewey-raw | 660.6 |
| dewey-search | 660.6 |
| dewey-sort | 3660.6 |
| dewey-tens | 660 - Chemical engineering |
| discipline | Chemie / Pharmazie |
| doi_str_mv | 10.1007/978-1-62703-299-5 |
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| isbn | 9781627032995 |
| language | English |
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| spelling | Systems Metabolic Engineering Methods and Protocols edited by Hal S. Alper Totowa, NJ Humana Press 2013 1 Online-Ressource (XII, 474 p. 61 illus., 47 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology, Methods and Protocols 985 With the ultimate goal of systematically and robustly defining the specific perturbations necessary to alter a cellular phenotype, systems metabolic engineering has the potential to lead to a complete cell model capable of simulating cell and metabolic function as well as predicting phenotypic response to changes in media, gene knockouts/overexpressions, or the incorporation of heterologous pathways. In Systems Metabolic Engineering: Methods and Protocols, experts in the field describe the methodologies and approaches in the area of systems metabolic engineering and provide a step-by-step guide for their implementation. Four major tenants of this approach are addressed, including modeling and simulation, multiplexed genome engineering, ‘omics technologies, and large data-set incorporation and synthesis, all elucidated through the use of model host organisms. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions on their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Systems Metabolic Engineering: Methods and Protocols serves as an ideal guide for metabolic engineers, molecular biologists, and microbiologists aiming to implement the most recent approaches available in the field Chemistry Biotechnology Microengineering Metabolomics Metabolism Alper, Hal S. edt Erscheint auch als Druck-Ausgabe 9781627032988 https://doi.org/10.1007/978-1-62703-299-5 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Systems Metabolic Engineering Methods and Protocols Chemistry Biotechnology Microengineering Metabolomics Metabolism |
| title | Systems Metabolic Engineering Methods and Protocols |
| title_auth | Systems Metabolic Engineering Methods and Protocols |
| title_exact_search | Systems Metabolic Engineering Methods and Protocols |
| title_full | Systems Metabolic Engineering Methods and Protocols edited by Hal S. Alper |
| title_fullStr | Systems Metabolic Engineering Methods and Protocols edited by Hal S. Alper |
| title_full_unstemmed | Systems Metabolic Engineering Methods and Protocols edited by Hal S. Alper |
| title_short | Systems Metabolic Engineering |
| title_sort | systems metabolic engineering methods and protocols |
| title_sub | Methods and Protocols |
| topic | Chemistry Biotechnology Microengineering Metabolomics Metabolism |
| topic_facet | Chemistry Biotechnology Microengineering Metabolomics Metabolism |
| url | https://doi.org/10.1007/978-1-62703-299-5 |
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