Functional Proteomics: Methods and Protocols
As the emerging field of proteomics continues to expand at an extremely rapid rate, the relative quantification of proteins, targeted by their function, becomes its greatest challenge. Complex analytical strategies have been designed that allow comparative analysis of large proteomes, as well as in...
Gespeichert in:
| Weitere Verfasser: | , , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2008
|
| Schriftenreihe: | Methods in Molecular Biology
484 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | As the emerging field of proteomics continues to expand at an extremely rapid rate, the relative quantification of proteins, targeted by their function, becomes its greatest challenge. Complex analytical strategies have been designed that allow comparative analysis of large proteomes, as well as in depth detection of the core proteome or the interaction network of a given protein of interest. In Functional Proteomics: Methods and Protocols, expert researchers describe the latest protocols being developed to address the problems encountered in high-throughput proteomics projects, with emphasis on the factors governing the technical choices for given applications. The case studies within the volume focus on the following three crucial aspects of the experimental design: 1) the strategy used for the selection, purification and preparation of the sample to be analyzed by mass spectrometry, 2) the type of mass spectrometer used and the type of data to be obtained from it, and 3) the method used for the interpretation of the mass spectrometry data and the search engine used for the identification of the proteins in the different types of sequence data banks available. As a part of the highly successful Methods in Molecular Biology™ series, the chapters compile step-by-step, readily reproducible laboratory protocols, lists of the necessary materials and reagents, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Functional Proteomics: Methods and Protocols is an ideal resource for all scientists pursuing this developing field and its multitudinous data |
| Beschreibung: | 1 Online-Ressource (XVIII, 596 p. 115 illus., 4 illus. in color) |
| ISBN: | 9781597453981 |
| DOI: | 10.1007/978-1-59745-398-1 |
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| 520 | |a As the emerging field of proteomics continues to expand at an extremely rapid rate, the relative quantification of proteins, targeted by their function, becomes its greatest challenge. Complex analytical strategies have been designed that allow comparative analysis of large proteomes, as well as in depth detection of the core proteome or the interaction network of a given protein of interest. In Functional Proteomics: Methods and Protocols, expert researchers describe the latest protocols being developed to address the problems encountered in high-throughput proteomics projects, with emphasis on the factors governing the technical choices for given applications. The case studies within the volume focus on the following three crucial aspects of the experimental design: 1) the strategy used for the selection, purification and preparation of the sample to be analyzed by mass spectrometry, 2) the type of mass spectrometer used and the type of data to be obtained from it, and 3) the method used for the interpretation of the mass spectrometry data and the search engine used for the identification of the proteins in the different types of sequence data banks available. As a part of the highly successful Methods in Molecular Biology™ series, the chapters compile step-by-step, readily reproducible laboratory protocols, lists of the necessary materials and reagents, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Functional Proteomics: Methods and Protocols is an ideal resource for all scientists pursuing this developing field and its multitudinous data | ||
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Datensatz im Suchindex
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| spelling | Functional Proteomics Methods and Protocols edited by Julie D. Thompson, Marius Ueffing, Christine Schaeffer-Reiss Totowa, NJ Humana Press 2008 1 Online-Ressource (XVIII, 596 p. 115 illus., 4 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 484 As the emerging field of proteomics continues to expand at an extremely rapid rate, the relative quantification of proteins, targeted by their function, becomes its greatest challenge. Complex analytical strategies have been designed that allow comparative analysis of large proteomes, as well as in depth detection of the core proteome or the interaction network of a given protein of interest. In Functional Proteomics: Methods and Protocols, expert researchers describe the latest protocols being developed to address the problems encountered in high-throughput proteomics projects, with emphasis on the factors governing the technical choices for given applications. The case studies within the volume focus on the following three crucial aspects of the experimental design: 1) the strategy used for the selection, purification and preparation of the sample to be analyzed by mass spectrometry, 2) the type of mass spectrometer used and the type of data to be obtained from it, and 3) the method used for the interpretation of the mass spectrometry data and the search engine used for the identification of the proteins in the different types of sequence data banks available. As a part of the highly successful Methods in Molecular Biology™ series, the chapters compile step-by-step, readily reproducible laboratory protocols, lists of the necessary materials and reagents, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Functional Proteomics: Methods and Protocols is an ideal resource for all scientists pursuing this developing field and its multitudinous data Life Sciences Biochemistry, general Protein Science Proteomics Mass Spectrometry Life sciences Mass spectrometry Biochemistry Proteins Proteomanalyse (DE-588)4596545-6 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Proteomanalyse (DE-588)4596545-6 s DE-604 Thompson, Julie D. edt Ueffing, Marius edt Schaeffer-Reiss, Christine edt Erscheint auch als Druck-Ausgabe 9781588299710 https://doi.org/10.1007/978-1-59745-398-1 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Functional Proteomics Methods and Protocols Life Sciences Biochemistry, general Protein Science Proteomics Mass Spectrometry Life sciences Mass spectrometry Biochemistry Proteins Proteomanalyse (DE-588)4596545-6 gnd |
| subject_GND | (DE-588)4596545-6 (DE-588)4143413-4 |
| title | Functional Proteomics Methods and Protocols |
| title_auth | Functional Proteomics Methods and Protocols |
| title_exact_search | Functional Proteomics Methods and Protocols |
| title_full | Functional Proteomics Methods and Protocols edited by Julie D. Thompson, Marius Ueffing, Christine Schaeffer-Reiss |
| title_fullStr | Functional Proteomics Methods and Protocols edited by Julie D. Thompson, Marius Ueffing, Christine Schaeffer-Reiss |
| title_full_unstemmed | Functional Proteomics Methods and Protocols edited by Julie D. Thompson, Marius Ueffing, Christine Schaeffer-Reiss |
| title_short | Functional Proteomics |
| title_sort | functional proteomics methods and protocols |
| title_sub | Methods and Protocols |
| topic | Life Sciences Biochemistry, general Protein Science Proteomics Mass Spectrometry Life sciences Mass spectrometry Biochemistry Proteins Proteomanalyse (DE-588)4596545-6 gnd |
| topic_facet | Life Sciences Biochemistry, general Protein Science Proteomics Mass Spectrometry Life sciences Mass spectrometry Biochemistry Proteins Proteomanalyse Aufsatzsammlung |
| url | https://doi.org/10.1007/978-1-59745-398-1 |
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