High Throughput Screening: Methods and Protocols
Since its first use in antibiotic research in the 1940s, High Throughput Screening (HTS) has evolved into a major enabling tool and methodology in the discovery of pharmaceutical, chemical, and agricultural compounds. In High Throughput Screening, leading scientists and researchers expert in molecul...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2002
|
| Schriftenreihe: | Methods in Molecular Biology™
190 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | Since its first use in antibiotic research in the 1940s, High Throughput Screening (HTS) has evolved into a major enabling tool and methodology in the discovery of pharmaceutical, chemical, and agricultural compounds. In High Throughput Screening, leading scientists and researchers expert in molecular discovery explain the diverse technologies and key techniques used in HTS and demonstrate how they can be applied generically. Writing to create precisely the introductory guidebook they wished had been available when they started in HTS, these seasoned authors illuminate the HTS process with richly detailed tutorials on the biological techniques involved, the management of compound libraries, and the automation and engineering approaches needed. Extensive discussions provide readers with all those key elements of pharmacology, molecular biology, enzymology, and biochemistry that will ensure the identification of suitable targets and screens, and detail the technology necessary to mine millions of data points for meaningful knowledge. By presenting accounts not only of the basic principles underlying HTS technology, but also real-use cases, High Throughput Screening constitutes a highly practical introduction to HTS, even as it also provides sufficient detail to work more productively in today's lead generation laboratories |
| Beschreibung: | 1 Online-Ressource (X, 265 p. 31 illus., 5 illus. in color) |
| ISBN: | 9781592591800 |
| DOI: | 10.1385/1592591809 |
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| 520 | |a Since its first use in antibiotic research in the 1940s, High Throughput Screening (HTS) has evolved into a major enabling tool and methodology in the discovery of pharmaceutical, chemical, and agricultural compounds. In High Throughput Screening, leading scientists and researchers expert in molecular discovery explain the diverse technologies and key techniques used in HTS and demonstrate how they can be applied generically. Writing to create precisely the introductory guidebook they wished had been available when they started in HTS, these seasoned authors illuminate the HTS process with richly detailed tutorials on the biological techniques involved, the management of compound libraries, and the automation and engineering approaches needed. Extensive discussions provide readers with all those key elements of pharmacology, molecular biology, enzymology, and biochemistry that will ensure the identification of suitable targets and screens, and detail the technology necessary to mine millions of data points for meaningful knowledge. By presenting accounts not only of the basic principles underlying HTS technology, but also real-use cases, High Throughput Screening constitutes a highly practical introduction to HTS, even as it also provides sufficient detail to work more productively in today's lead generation laboratories | ||
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| spelling | High Throughput Screening Methods and Protocols edited by William P. Janzen Totowa, NJ Humana Press 2002 1 Online-Ressource (X, 265 p. 31 illus., 5 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology™ 190 Since its first use in antibiotic research in the 1940s, High Throughput Screening (HTS) has evolved into a major enabling tool and methodology in the discovery of pharmaceutical, chemical, and agricultural compounds. In High Throughput Screening, leading scientists and researchers expert in molecular discovery explain the diverse technologies and key techniques used in HTS and demonstrate how they can be applied generically. Writing to create precisely the introductory guidebook they wished had been available when they started in HTS, these seasoned authors illuminate the HTS process with richly detailed tutorials on the biological techniques involved, the management of compound libraries, and the automation and engineering approaches needed. Extensive discussions provide readers with all those key elements of pharmacology, molecular biology, enzymology, and biochemistry that will ensure the identification of suitable targets and screens, and detail the technology necessary to mine millions of data points for meaningful knowledge. By presenting accounts not only of the basic principles underlying HTS technology, but also real-use cases, High Throughput Screening constitutes a highly practical introduction to HTS, even as it also provides sufficient detail to work more productively in today's lead generation laboratories Pharmacy High throughput screening (DE-588)4596131-1 gnd rswk-swf Arzneimittelentwicklung (DE-588)4143176-5 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content High throughput screening (DE-588)4596131-1 s Arzneimittelentwicklung (DE-588)4143176-5 s DE-604 Janzen, William P. edt Erscheint auch als Druck-Ausgabe 9780896038899 https://doi.org/10.1385/1592591809 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | High Throughput Screening Methods and Protocols Pharmacy High throughput screening (DE-588)4596131-1 gnd Arzneimittelentwicklung (DE-588)4143176-5 gnd |
| subject_GND | (DE-588)4596131-1 (DE-588)4143176-5 (DE-588)4143413-4 |
| title | High Throughput Screening Methods and Protocols |
| title_auth | High Throughput Screening Methods and Protocols |
| title_exact_search | High Throughput Screening Methods and Protocols |
| title_full | High Throughput Screening Methods and Protocols edited by William P. Janzen |
| title_fullStr | High Throughput Screening Methods and Protocols edited by William P. Janzen |
| title_full_unstemmed | High Throughput Screening Methods and Protocols edited by William P. Janzen |
| title_short | High Throughput Screening |
| title_sort | high throughput screening methods and protocols |
| title_sub | Methods and Protocols |
| topic | Pharmacy High throughput screening (DE-588)4596131-1 gnd Arzneimittelentwicklung (DE-588)4143176-5 gnd |
| topic_facet | Pharmacy High throughput screening Arzneimittelentwicklung Aufsatzsammlung |
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