Microbial Gene Essentiality: Protocols and Bioinformatics:
Microbial Gene Essentiality: Protocols and Bioinformatics contains a comprehensive collection of experimental and computational strategies and techniques for microbial genome-scale essentiality studies, developed and presented by the leading groups in the field. In addition to wet-lab protocols, the...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2008
|
| Schriftenreihe: | Methods in Molecular Biology™
416 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | Microbial Gene Essentiality: Protocols and Bioinformatics contains a comprehensive collection of experimental and computational strategies and techniques for microbial genome-scale essentiality studies, developed and presented by the leading groups in the field. In addition to wet-lab protocols, the book describes (i) statistical methods essential for planning successful large-scale essentiality screens, as well for data evaluation and analysis; (ii) in-silico prediction of gene essentiality using genome-scale reconstructed metabolic models; and (iii) data integration and comparative analysis in the context of genomic databases. This volume provides researchers with a first-stop guide for choosing the most appropriate strategy for planned essentiality studies. Experimental and computational aspects are equally important in genome-scale gene essentiality analysis, as in all other genomic technologies, and Microbial Gene Essentiality: Protocols and Bioinformatics reflects both of these aspects. All protocols follow the successful Methods in Molecular Biology™ series format, each offering an introduction outlining the principles behind the techniques, step-by-step instructions, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding pitfalls, and are intended for both novice and expert scientists |
| Beschreibung: | 1 Online-Ressource (XIV, 486 p) |
| ISBN: | 9781597453219 |
| DOI: | 10.1007/978-1-59745-321-9 |
Internformat
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Datensatz im Suchindex
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| author2 | Osterman, Andrei L. Gerdes, Svetlana Y. |
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| indexdate | 2024-07-10T08:05:35Z |
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| isbn | 9781597453219 |
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| spelling | Microbial Gene Essentiality: Protocols and Bioinformatics edited by Andrei L. Osterman, Svetlana Y. Gerdes Totowa, NJ Humana Press 2008 1 Online-Ressource (XIV, 486 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology™ 416 Microbial Gene Essentiality: Protocols and Bioinformatics contains a comprehensive collection of experimental and computational strategies and techniques for microbial genome-scale essentiality studies, developed and presented by the leading groups in the field. In addition to wet-lab protocols, the book describes (i) statistical methods essential for planning successful large-scale essentiality screens, as well for data evaluation and analysis; (ii) in-silico prediction of gene essentiality using genome-scale reconstructed metabolic models; and (iii) data integration and comparative analysis in the context of genomic databases. This volume provides researchers with a first-stop guide for choosing the most appropriate strategy for planned essentiality studies. Experimental and computational aspects are equally important in genome-scale gene essentiality analysis, as in all other genomic technologies, and Microbial Gene Essentiality: Protocols and Bioinformatics reflects both of these aspects. All protocols follow the successful Methods in Molecular Biology™ series format, each offering an introduction outlining the principles behind the techniques, step-by-step instructions, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding pitfalls, and are intended for both novice and expert scientists Life Sciences Biochemistry, general Cell Biology Human Genetics Life sciences Human genetics Biochemistry Cell biology Mikroorganismus (DE-588)4039226-0 gnd rswk-swf Genanalyse (DE-588)4200230-8 gnd rswk-swf Bioinformatik (DE-588)4611085-9 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Mikroorganismus (DE-588)4039226-0 s Genanalyse (DE-588)4200230-8 s 2\p DE-604 Bioinformatik (DE-588)4611085-9 s 3\p DE-604 Osterman, Andrei L. edt Gerdes, Svetlana Y. edt Erscheint auch als Druck-Ausgabe 9781588293787 https://doi.org/10.1007/978-1-59745-321-9 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 3\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Microbial Gene Essentiality: Protocols and Bioinformatics Life Sciences Biochemistry, general Cell Biology Human Genetics Life sciences Human genetics Biochemistry Cell biology Mikroorganismus (DE-588)4039226-0 gnd Genanalyse (DE-588)4200230-8 gnd Bioinformatik (DE-588)4611085-9 gnd |
| subject_GND | (DE-588)4039226-0 (DE-588)4200230-8 (DE-588)4611085-9 (DE-588)4143413-4 |
| title | Microbial Gene Essentiality: Protocols and Bioinformatics |
| title_auth | Microbial Gene Essentiality: Protocols and Bioinformatics |
| title_exact_search | Microbial Gene Essentiality: Protocols and Bioinformatics |
| title_full | Microbial Gene Essentiality: Protocols and Bioinformatics edited by Andrei L. Osterman, Svetlana Y. Gerdes |
| title_fullStr | Microbial Gene Essentiality: Protocols and Bioinformatics edited by Andrei L. Osterman, Svetlana Y. Gerdes |
| title_full_unstemmed | Microbial Gene Essentiality: Protocols and Bioinformatics edited by Andrei L. Osterman, Svetlana Y. Gerdes |
| title_short | Microbial Gene Essentiality: Protocols and Bioinformatics |
| title_sort | microbial gene essentiality protocols and bioinformatics |
| topic | Life Sciences Biochemistry, general Cell Biology Human Genetics Life sciences Human genetics Biochemistry Cell biology Mikroorganismus (DE-588)4039226-0 gnd Genanalyse (DE-588)4200230-8 gnd Bioinformatik (DE-588)4611085-9 gnd |
| topic_facet | Life Sciences Biochemistry, general Cell Biology Human Genetics Life sciences Human genetics Biochemistry Cell biology Mikroorganismus Genanalyse Bioinformatik Aufsatzsammlung |
| url | https://doi.org/10.1007/978-1-59745-321-9 |
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