Mammalian Chromosome Engineering: Methods and Protocols
The rapid progression of genetics and molecular biology has turned chromosomal engineering from science fiction to reality, with the successful production of transgenic animals with engineered chromosomes and chromosomes developed for pharmaceutical protein production which are now ready for the med...
Gespeichert in:
Weitere Verfasser: | |
---|---|
Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Totowa, NJ
Humana Press
2011
|
Schriftenreihe: | Methods in Molecular Biology, Methods and Protocols
738 |
Schlagworte: | |
Online-Zugang: | TUM01 UBR01 Volltext |
Zusammenfassung: | The rapid progression of genetics and molecular biology has turned chromosomal engineering from science fiction to reality, with the successful production of transgenic animals with engineered chromosomes and chromosomes developed for pharmaceutical protein production which are now ready for the medical industry. Mammalian Chromosome Engineering: Methods and Protocols provides the reader with up-to date information on this rapidly evolving field and strives to take the reader into the exciting realm of chromosomal engineering from the basic principles to the practical applications of these new technologies. The five overview and ten protocol chapters cover the engineering of chromosomes with extrachromosomal vectors and transposon systems, the manipulation of naturally occurred minichromosomes, the generation and engineering of synthetic artificial chromosomes, and the induced de novo platform artificial chromosome system. Written in the highly successful Methods in Molecular Biology™ series format, protocols chapters contain brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mammalian Chromosome Engineering: Methods and Protocols serves as a bench-side resource for current protocols and aims to help scientists to explore the many prospects for future research and vital applications |
Beschreibung: | 1 Online-Ressource (IX, 257 p. 48 illus., 3 illus. in color) |
ISBN: | 9781617790997 |
DOI: | 10.1007/978-1-61779-099-7 |
Internformat
MARC
LEADER | 00000nmm a2200000zcb4500 | ||
---|---|---|---|
001 | BV044951244 | ||
003 | DE-604 | ||
005 | 00000000000000.0 | ||
007 | cr|uuu---uuuuu | ||
008 | 180517s2011 |||| o||u| ||||||eng d | ||
020 | |a 9781617790997 |9 978-1-61779-099-7 | ||
024 | 7 | |a 10.1007/978-1-61779-099-7 |2 doi | |
035 | |a (ZDB-2-PRO)978-1-61779-099-7 | ||
035 | |a (OCoLC)891106374 | ||
035 | |a (DE-599)BVBBV044951244 | ||
040 | |a DE-604 |b ger |e rda | ||
041 | 0 | |a eng | |
049 | |a DE-91 |a DE-355 | ||
082 | 0 | |a 611.01816 |2 23 | |
082 | 0 | |a 599.935 |2 23 | |
245 | 1 | 0 | |a Mammalian Chromosome Engineering |b Methods and Protocols |c edited by Gyula Hadlaczky |
264 | 1 | |a Totowa, NJ |b Humana Press |c 2011 | |
300 | |a 1 Online-Ressource (IX, 257 p. 48 illus., 3 illus. in color) | ||
336 | |b txt |2 rdacontent | ||
337 | |b c |2 rdamedia | ||
338 | |b cr |2 rdacarrier | ||
490 | 0 | |a Methods in Molecular Biology, Methods and Protocols |v 738 | |
520 | |a The rapid progression of genetics and molecular biology has turned chromosomal engineering from science fiction to reality, with the successful production of transgenic animals with engineered chromosomes and chromosomes developed for pharmaceutical protein production which are now ready for the medical industry. Mammalian Chromosome Engineering: Methods and Protocols provides the reader with up-to date information on this rapidly evolving field and strives to take the reader into the exciting realm of chromosomal engineering from the basic principles to the practical applications of these new technologies. The five overview and ten protocol chapters cover the engineering of chromosomes with extrachromosomal vectors and transposon systems, the manipulation of naturally occurred minichromosomes, the generation and engineering of synthetic artificial chromosomes, and the induced de novo platform artificial chromosome system. Written in the highly successful Methods in Molecular Biology™ series format, protocols chapters contain brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mammalian Chromosome Engineering: Methods and Protocols serves as a bench-side resource for current protocols and aims to help scientists to explore the many prospects for future research and vital applications | ||
650 | 4 | |a Biomedicine | |
650 | 4 | |a Human Genetics | |
650 | 4 | |a Genetic Engineering | |
650 | 4 | |a Medicine | |
650 | 4 | |a Human genetics | |
650 | 4 | |a Genetic engineering | |
700 | 1 | |a Hadlaczky, Gyula |4 edt | |
776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781617790980 |
856 | 4 | 0 | |u https://doi.org/10.1007/978-1-61779-099-7 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
912 | |a ZDB-2-PRO | ||
999 | |a oai:aleph.bib-bvb.de:BVB01-030344002 | ||
966 | e | |u https://doi.org/10.1007/978-1-61779-099-7 |l TUM01 |p ZDB-2-PRO |x Verlag |3 Volltext | |
966 | e | |u https://doi.org/10.1007/978-1-61779-099-7 |l UBR01 |p ZDB-2-PRO |x Verlag |3 Volltext |
Datensatz im Suchindex
_version_ | 1804178539627413504 |
---|---|
any_adam_object | |
author2 | Hadlaczky, Gyula |
author2_role | edt |
author2_variant | g h gh |
author_facet | Hadlaczky, Gyula |
building | Verbundindex |
bvnumber | BV044951244 |
collection | ZDB-2-PRO |
ctrlnum | (ZDB-2-PRO)978-1-61779-099-7 (OCoLC)891106374 (DE-599)BVBBV044951244 |
dewey-full | 611.01816 599.935 |
dewey-hundreds | 600 - Technology (Applied sciences) 500 - Natural sciences and mathematics |
dewey-ones | 611 - Human anatomy, cytology, histology 599 - Mammalia |
dewey-raw | 611.01816 599.935 |
dewey-search | 611.01816 599.935 |
dewey-sort | 3611.01816 |
dewey-tens | 610 - Medicine and health 590 - Animals |
discipline | Biologie Medizin |
doi_str_mv | 10.1007/978-1-61779-099-7 |
format | Electronic eBook |
fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03102nmm a2200457zcb4500</leader><controlfield tag="001">BV044951244</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">180517s2011 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781617790997</subfield><subfield code="9">978-1-61779-099-7</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/978-1-61779-099-7</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-2-PRO)978-1-61779-099-7</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)891106374</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV044951244</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-91</subfield><subfield code="a">DE-355</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">611.01816</subfield><subfield code="2">23</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">599.935</subfield><subfield code="2">23</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Mammalian Chromosome Engineering</subfield><subfield code="b">Methods and Protocols</subfield><subfield code="c">edited by Gyula Hadlaczky</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Totowa, NJ</subfield><subfield code="b">Humana Press</subfield><subfield code="c">2011</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (IX, 257 p. 48 illus., 3 illus. in color)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Methods in Molecular Biology, Methods and Protocols</subfield><subfield code="v">738</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The rapid progression of genetics and molecular biology has turned chromosomal engineering from science fiction to reality, with the successful production of transgenic animals with engineered chromosomes and chromosomes developed for pharmaceutical protein production which are now ready for the medical industry. Mammalian Chromosome Engineering: Methods and Protocols provides the reader with up-to date information on this rapidly evolving field and strives to take the reader into the exciting realm of chromosomal engineering from the basic principles to the practical applications of these new technologies. The five overview and ten protocol chapters cover the engineering of chromosomes with extrachromosomal vectors and transposon systems, the manipulation of naturally occurred minichromosomes, the generation and engineering of synthetic artificial chromosomes, and the induced de novo platform artificial chromosome system. Written in the highly successful Methods in Molecular Biology™ series format, protocols chapters contain brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mammalian Chromosome Engineering: Methods and Protocols serves as a bench-side resource for current protocols and aims to help scientists to explore the many prospects for future research and vital applications</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Biomedicine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Human Genetics</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Genetic Engineering</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Medicine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Human genetics</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Genetic engineering</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hadlaczky, Gyula</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9781617790980</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1007/978-1-61779-099-7</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-2-PRO</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-030344002</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-1-61779-099-7</subfield><subfield code="l">TUM01</subfield><subfield code="p">ZDB-2-PRO</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-1-61779-099-7</subfield><subfield code="l">UBR01</subfield><subfield code="p">ZDB-2-PRO</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
id | DE-604.BV044951244 |
illustrated | Not Illustrated |
indexdate | 2024-07-10T08:05:35Z |
institution | BVB |
isbn | 9781617790997 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-030344002 |
oclc_num | 891106374 |
open_access_boolean | |
owner | DE-91 DE-BY-TUM DE-355 DE-BY-UBR |
owner_facet | DE-91 DE-BY-TUM DE-355 DE-BY-UBR |
physical | 1 Online-Ressource (IX, 257 p. 48 illus., 3 illus. in color) |
psigel | ZDB-2-PRO |
publishDate | 2011 |
publishDateSearch | 2011 |
publishDateSort | 2011 |
publisher | Humana Press |
record_format | marc |
series2 | Methods in Molecular Biology, Methods and Protocols |
spelling | Mammalian Chromosome Engineering Methods and Protocols edited by Gyula Hadlaczky Totowa, NJ Humana Press 2011 1 Online-Ressource (IX, 257 p. 48 illus., 3 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology, Methods and Protocols 738 The rapid progression of genetics and molecular biology has turned chromosomal engineering from science fiction to reality, with the successful production of transgenic animals with engineered chromosomes and chromosomes developed for pharmaceutical protein production which are now ready for the medical industry. Mammalian Chromosome Engineering: Methods and Protocols provides the reader with up-to date information on this rapidly evolving field and strives to take the reader into the exciting realm of chromosomal engineering from the basic principles to the practical applications of these new technologies. The five overview and ten protocol chapters cover the engineering of chromosomes with extrachromosomal vectors and transposon systems, the manipulation of naturally occurred minichromosomes, the generation and engineering of synthetic artificial chromosomes, and the induced de novo platform artificial chromosome system. Written in the highly successful Methods in Molecular Biology™ series format, protocols chapters contain brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mammalian Chromosome Engineering: Methods and Protocols serves as a bench-side resource for current protocols and aims to help scientists to explore the many prospects for future research and vital applications Biomedicine Human Genetics Genetic Engineering Medicine Human genetics Genetic engineering Hadlaczky, Gyula edt Erscheint auch als Druck-Ausgabe 9781617790980 https://doi.org/10.1007/978-1-61779-099-7 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Mammalian Chromosome Engineering Methods and Protocols Biomedicine Human Genetics Genetic Engineering Medicine Human genetics Genetic engineering |
title | Mammalian Chromosome Engineering Methods and Protocols |
title_auth | Mammalian Chromosome Engineering Methods and Protocols |
title_exact_search | Mammalian Chromosome Engineering Methods and Protocols |
title_full | Mammalian Chromosome Engineering Methods and Protocols edited by Gyula Hadlaczky |
title_fullStr | Mammalian Chromosome Engineering Methods and Protocols edited by Gyula Hadlaczky |
title_full_unstemmed | Mammalian Chromosome Engineering Methods and Protocols edited by Gyula Hadlaczky |
title_short | Mammalian Chromosome Engineering |
title_sort | mammalian chromosome engineering methods and protocols |
title_sub | Methods and Protocols |
topic | Biomedicine Human Genetics Genetic Engineering Medicine Human genetics Genetic engineering |
topic_facet | Biomedicine Human Genetics Genetic Engineering Medicine Human genetics Genetic engineering |
url | https://doi.org/10.1007/978-1-61779-099-7 |
work_keys_str_mv | AT hadlaczkygyula mammalianchromosomeengineeringmethodsandprotocols |