siRNA and miRNA Gene Silencing: From Bench to Bedside
RNA interference has become a key method in the suppression of gene expression and the development of therapeutic agents, yet there is still the problem of delivery, stability, and the danger of off-target effects such as the silencing of unwanted genes and activation of innate immunity. In siRNA an...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2009
|
| Schriftenreihe: | Methods in Molecular Biology, Methods and Protocols
487 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | RNA interference has become a key method in the suppression of gene expression and the development of therapeutic agents, yet there is still the problem of delivery, stability, and the danger of off-target effects such as the silencing of unwanted genes and activation of innate immunity. In siRNA and miRNA Gene Silencing: From Bench to Bedside, expert researchers explore the most recent advances in siRNA design, expression, delivery, in vivo imaging, and methods to minimize siRNA's unwanted effects and promote successful use in patients. As part of the highly successful Methods in Molecular Biology™ series, the chapters focus on their respective subjects with easy-to-use, up-to-date information, including several step-by-step laboratory protocols on topics such as new delivery formulations and strategies with promising applications in vitro and in vivo, validated therapeutic target genes, and components of miRNA function, biogenesis, and interference with virus infection. Comprehensive and cutting-edge, siRNA and miRNA Gene Silencing: From Bench to Bedside offers an excellent collection of chapters to aid all those with an interest in RNAi, gene regulation, and new therapies |
| Beschreibung: | 1 Online-Ressource (XIV, 472 p) |
| ISBN: | 9781603275477 |
| DOI: | 10.1007/978-1-60327-547-7 |
Internformat
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| spelling | siRNA and miRNA Gene Silencing From Bench to Bedside edited by Mouldy Sioud Totowa, NJ Humana Press 2009 1 Online-Ressource (XIV, 472 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology, Methods and Protocols 487 RNA interference has become a key method in the suppression of gene expression and the development of therapeutic agents, yet there is still the problem of delivery, stability, and the danger of off-target effects such as the silencing of unwanted genes and activation of innate immunity. In siRNA and miRNA Gene Silencing: From Bench to Bedside, expert researchers explore the most recent advances in siRNA design, expression, delivery, in vivo imaging, and methods to minimize siRNA's unwanted effects and promote successful use in patients. As part of the highly successful Methods in Molecular Biology™ series, the chapters focus on their respective subjects with easy-to-use, up-to-date information, including several step-by-step laboratory protocols on topics such as new delivery formulations and strategies with promising applications in vitro and in vivo, validated therapeutic target genes, and components of miRNA function, biogenesis, and interference with virus infection. Comprehensive and cutting-edge, siRNA and miRNA Gene Silencing: From Bench to Bedside offers an excellent collection of chapters to aid all those with an interest in RNAi, gene regulation, and new therapies Life Sciences Biochemistry, general Human Genetics Gene Expression Life sciences Human genetics Gene expression Biochemistry RNS-Interferenz (DE-588)4802706-6 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content RNS-Interferenz (DE-588)4802706-6 s b DE-604 Sioud, Mouldy edt Erscheint auch als Druck-Ausgabe 9781603275460 https://doi.org/10.1007/978-1-60327-547-7 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | siRNA and miRNA Gene Silencing From Bench to Bedside Life Sciences Biochemistry, general Human Genetics Gene Expression Life sciences Human genetics Gene expression Biochemistry RNS-Interferenz (DE-588)4802706-6 gnd |
| subject_GND | (DE-588)4802706-6 (DE-588)4143413-4 |
| title | siRNA and miRNA Gene Silencing From Bench to Bedside |
| title_auth | siRNA and miRNA Gene Silencing From Bench to Bedside |
| title_exact_search | siRNA and miRNA Gene Silencing From Bench to Bedside |
| title_full | siRNA and miRNA Gene Silencing From Bench to Bedside edited by Mouldy Sioud |
| title_fullStr | siRNA and miRNA Gene Silencing From Bench to Bedside edited by Mouldy Sioud |
| title_full_unstemmed | siRNA and miRNA Gene Silencing From Bench to Bedside edited by Mouldy Sioud |
| title_short | siRNA and miRNA Gene Silencing |
| title_sort | sirna and mirna gene silencing from bench to bedside |
| title_sub | From Bench to Bedside |
| topic | Life Sciences Biochemistry, general Human Genetics Gene Expression Life sciences Human genetics Gene expression Biochemistry RNS-Interferenz (DE-588)4802706-6 gnd |
| topic_facet | Life Sciences Biochemistry, general Human Genetics Gene Expression Life sciences Human genetics Gene expression Biochemistry RNS-Interferenz Aufsatzsammlung |
| url | https://doi.org/10.1007/978-1-60327-547-7 |
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