Protocols for Oligonucleotides and Analogs: Synthesis and Properties
When first conceived, not only was the aim of Protocols for Oligo nucleotides and Analogs to provide wide coverage of the ohgonuc- otide chemistry field for readers who are well versed within the field, but also to give investigators just entering into the field a new perspective. The very first bo...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
1993
|
| Schriftenreihe: | Methods in Molecular Biology
20 |
| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | When first conceived, not only was the aim of Protocols for Oligo nucleotides and Analogs to provide wide coverage of the ohgonuc- otide chemistry field for readers who are well versed within the field, but also to give investigators just entering into the field a new perspective. The very first book on this topic was edited and published by Michael Gait in 1984, in whose laboratory I encountered the newer aspects of oligonucleotide chemistry. Since then, oligonucleotide research has developed to such an extent that its uses extend far beyond basic studies, and now find wide application throughout clinical science as well. Until recently, the major application of oligonucleotides has been in the area of DNA-based diagnostic and "antisense oligonucleotid- based therapeutic approaches. However, oligonucleotides are now also being used as therapeutic agents and are thus frequently found in clinical trials in humans. Synthesis of unmodified oligonucleotides using automated synthe sizers has become a common practice in numerous laboratories. How ever, improvements on the existing techniques and the introduction of ever newer methods for oligonucleotide synthesis is constantly driving ahead in the leading research laboratories. And several new oligonucle otide analogs have been synthesized and studied for their individual prop erties in recent years. The present volume strives to bring the readers the most up-to-date information on the newest aspects of synthesis of oligo nucleotides and their analogs. A separate volume covers synthesis of oligonucleotide conjugates, along with most of the analytical techniques presently used for analysis of oligonucleotides |
| Beschreibung: | 1 Online-Ressource (XIV, 502 p) |
| ISBN: | 9781592595075 |
| DOI: | 10.1385/0896032817 |
Internformat
MARC
| LEADER | 00000nmm a2200000zcb4500 | ||
|---|---|---|---|
| 001 | BV044951127 | ||
| 003 | DE-604 | ||
| 005 | 20180829 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 180517s1993 |||| o||u| ||||||eng d | ||
| 020 | |a 9781592595075 |9 978-1-59259-507-5 | ||
| 024 | 7 | |a 10.1385/0896032817 |2 doi | |
| 035 | |a (ZDB-2-PRO)978-1-59259-507-5 | ||
| 035 | |a (OCoLC)1036360897 | ||
| 035 | |a (DE-599)BVBBV044951127 | ||
| 040 | |a DE-604 |b ger |e rda | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 | ||
| 050 | 0 | |a QP625.O47 | |
| 082 | 0 | |a 547 |2 23 | |
| 082 | 0 | |a 547.7/9 |2 20 | |
| 084 | |a VK 8570 |0 (DE-625)147541:253 |2 rvk | ||
| 084 | |a WC 4150 |0 (DE-625)148092: |2 rvk | ||
| 245 | 1 | 0 | |a Protocols for Oligonucleotides and Analogs |b Synthesis and Properties |c edited by Sudhir Agrawal |
| 264 | 1 | |a Totowa, NJ |b Humana Press |c 1993 | |
| 300 | |a 1 Online-Ressource (XIV, 502 p) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 490 | 0 | |a Methods in Molecular Biology |v 20 | |
| 520 | |a When first conceived, not only was the aim of Protocols for Oligo nucleotides and Analogs to provide wide coverage of the ohgonuc- otide chemistry field for readers who are well versed within the field, but also to give investigators just entering into the field a new perspective. The very first book on this topic was edited and published by Michael Gait in 1984, in whose laboratory I encountered the newer aspects of oligonucleotide chemistry. Since then, oligonucleotide research has developed to such an extent that its uses extend far beyond basic studies, and now find wide application throughout clinical science as well. Until recently, the major application of oligonucleotides has been in the area of DNA-based diagnostic and "antisense oligonucleotid- based therapeutic approaches. However, oligonucleotides are now also being used as therapeutic agents and are thus frequently found in clinical trials in humans. Synthesis of unmodified oligonucleotides using automated synthe sizers has become a common practice in numerous laboratories. How ever, improvements on the existing techniques and the introduction of ever newer methods for oligonucleotide synthesis is constantly driving ahead in the leading research laboratories. And several new oligonucle otide analogs have been synthesized and studied for their individual prop erties in recent years. The present volume strives to bring the readers the most up-to-date information on the newest aspects of synthesis of oligo nucleotides and their analogs. A separate volume covers synthesis of oligonucleotide conjugates, along with most of the analytical techniques presently used for analysis of oligonucleotides | ||
| 650 | 4 | |a Chemistry | |
| 650 | 4 | |a Organic Chemistry | |
| 650 | 4 | |a Chemistry | |
| 650 | 4 | |a Organic chemistry | |
| 650 | 0 | 7 | |a Oligonucleotide |0 (DE-588)4133456-5 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Chemische Synthese |0 (DE-588)4133806-6 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Oligonucleotide |0 (DE-588)4133456-5 |D s |
| 689 | 0 | 1 | |a Chemische Synthese |0 (DE-588)4133806-6 |D s |
| 689 | 0 | |5 DE-604 | |
| 700 | 1 | |a Agrawal, Sudhir |4 edt | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9780896032811 |
| 856 | 4 | 0 | |u https://doi.org/10.1385/0896032817 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
| 912 | |a ZDB-2-PRO | ||
| 999 | |a oai:aleph.bib-bvb.de:BVB01-030343886 | ||
| 966 | e | |u https://doi.org/10.1385/0896032817 |l UBR01 |p ZDB-2-PRO |x Verlag |3 Volltext | |
Datensatz im Suchindex
| _version_ | 1804178539376803840 |
|---|---|
| any_adam_object | |
| author2 | Agrawal, Sudhir |
| author2_role | edt |
| author2_variant | s a sa |
| author_facet | Agrawal, Sudhir |
| building | Verbundindex |
| bvnumber | BV044951127 |
| callnumber-first | Q - Science |
| callnumber-label | QP625 |
| callnumber-raw | QP625.O47 |
| callnumber-search | QP625.O47 |
| callnumber-sort | QP 3625 O47 |
| callnumber-subject | QP - Physiology |
| classification_rvk | VK 8570 WC 4150 |
| collection | ZDB-2-PRO |
| ctrlnum | (ZDB-2-PRO)978-1-59259-507-5 (OCoLC)1036360897 (DE-599)BVBBV044951127 |
| dewey-full | 547 547.7/9 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 547 - Organic chemistry |
| dewey-raw | 547 547.7/9 |
| dewey-search | 547 547.7/9 |
| dewey-sort | 3547 |
| dewey-tens | 540 - Chemistry and allied sciences |
| discipline | Chemie / Pharmazie Biologie |
| doi_str_mv | 10.1385/0896032817 |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03446nmm a2200517zcb4500</leader><controlfield tag="001">BV044951127</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20180829 </controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">180517s1993 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781592595075</subfield><subfield code="9">978-1-59259-507-5</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1385/0896032817</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-2-PRO)978-1-59259-507-5</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1036360897</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV044951127</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">QP625.O47</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">547</subfield><subfield code="2">23</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">547.7/9</subfield><subfield code="2">20</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">VK 8570</subfield><subfield code="0">(DE-625)147541:253</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WC 4150</subfield><subfield code="0">(DE-625)148092:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Protocols for Oligonucleotides and Analogs</subfield><subfield code="b">Synthesis and Properties</subfield><subfield code="c">edited by Sudhir Agrawal</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Totowa, NJ</subfield><subfield code="b">Humana Press</subfield><subfield code="c">1993</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (XIV, 502 p)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Methods in Molecular Biology</subfield><subfield code="v">20</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">When first conceived, not only was the aim of Protocols for Oligo nucleotides and Analogs to provide wide coverage of the ohgonuc- otide chemistry field for readers who are well versed within the field, but also to give investigators just entering into the field a new perspective. The very first book on this topic was edited and published by Michael Gait in 1984, in whose laboratory I encountered the newer aspects of oligonucleotide chemistry. Since then, oligonucleotide research has developed to such an extent that its uses extend far beyond basic studies, and now find wide application throughout clinical science as well. Until recently, the major application of oligonucleotides has been in the area of DNA-based diagnostic and "antisense oligonucleotid- based therapeutic approaches. However, oligonucleotides are now also being used as therapeutic agents and are thus frequently found in clinical trials in humans. Synthesis of unmodified oligonucleotides using automated synthe sizers has become a common practice in numerous laboratories. How ever, improvements on the existing techniques and the introduction of ever newer methods for oligonucleotide synthesis is constantly driving ahead in the leading research laboratories. And several new oligonucle otide analogs have been synthesized and studied for their individual prop erties in recent years. The present volume strives to bring the readers the most up-to-date information on the newest aspects of synthesis of oligo nucleotides and their analogs. A separate volume covers synthesis of oligonucleotide conjugates, along with most of the analytical techniques presently used for analysis of oligonucleotides</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Chemistry</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Organic Chemistry</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Chemistry</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Organic chemistry</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Oligonucleotide</subfield><subfield code="0">(DE-588)4133456-5</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Chemische Synthese</subfield><subfield code="0">(DE-588)4133806-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Oligonucleotide</subfield><subfield code="0">(DE-588)4133456-5</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Chemische Synthese</subfield><subfield code="0">(DE-588)4133806-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Agrawal, Sudhir</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9780896032811</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1385/0896032817</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-2-PRO</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-030343886</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1385/0896032817</subfield><subfield code="l">UBR01</subfield><subfield code="p">ZDB-2-PRO</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| id | DE-604.BV044951127 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:05:35Z |
| institution | BVB |
| isbn | 9781592595075 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-030343886 |
| oclc_num | 1036360897 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR |
| owner_facet | DE-355 DE-BY-UBR |
| physical | 1 Online-Ressource (XIV, 502 p) |
| psigel | ZDB-2-PRO |
| publishDate | 1993 |
| publishDateSearch | 1993 |
| publishDateSort | 1993 |
| publisher | Humana Press |
| record_format | marc |
| series2 | Methods in Molecular Biology |
| spelling | Protocols for Oligonucleotides and Analogs Synthesis and Properties edited by Sudhir Agrawal Totowa, NJ Humana Press 1993 1 Online-Ressource (XIV, 502 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 20 When first conceived, not only was the aim of Protocols for Oligo nucleotides and Analogs to provide wide coverage of the ohgonuc- otide chemistry field for readers who are well versed within the field, but also to give investigators just entering into the field a new perspective. The very first book on this topic was edited and published by Michael Gait in 1984, in whose laboratory I encountered the newer aspects of oligonucleotide chemistry. Since then, oligonucleotide research has developed to such an extent that its uses extend far beyond basic studies, and now find wide application throughout clinical science as well. Until recently, the major application of oligonucleotides has been in the area of DNA-based diagnostic and "antisense oligonucleotid- based therapeutic approaches. However, oligonucleotides are now also being used as therapeutic agents and are thus frequently found in clinical trials in humans. Synthesis of unmodified oligonucleotides using automated synthe sizers has become a common practice in numerous laboratories. How ever, improvements on the existing techniques and the introduction of ever newer methods for oligonucleotide synthesis is constantly driving ahead in the leading research laboratories. And several new oligonucle otide analogs have been synthesized and studied for their individual prop erties in recent years. The present volume strives to bring the readers the most up-to-date information on the newest aspects of synthesis of oligo nucleotides and their analogs. A separate volume covers synthesis of oligonucleotide conjugates, along with most of the analytical techniques presently used for analysis of oligonucleotides Chemistry Organic Chemistry Organic chemistry Oligonucleotide (DE-588)4133456-5 gnd rswk-swf Chemische Synthese (DE-588)4133806-6 gnd rswk-swf Oligonucleotide (DE-588)4133456-5 s Chemische Synthese (DE-588)4133806-6 s DE-604 Agrawal, Sudhir edt Erscheint auch als Druck-Ausgabe 9780896032811 https://doi.org/10.1385/0896032817 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Protocols for Oligonucleotides and Analogs Synthesis and Properties Chemistry Organic Chemistry Organic chemistry Oligonucleotide (DE-588)4133456-5 gnd Chemische Synthese (DE-588)4133806-6 gnd |
| subject_GND | (DE-588)4133456-5 (DE-588)4133806-6 |
| title | Protocols for Oligonucleotides and Analogs Synthesis and Properties |
| title_auth | Protocols for Oligonucleotides and Analogs Synthesis and Properties |
| title_exact_search | Protocols for Oligonucleotides and Analogs Synthesis and Properties |
| title_full | Protocols for Oligonucleotides and Analogs Synthesis and Properties edited by Sudhir Agrawal |
| title_fullStr | Protocols for Oligonucleotides and Analogs Synthesis and Properties edited by Sudhir Agrawal |
| title_full_unstemmed | Protocols for Oligonucleotides and Analogs Synthesis and Properties edited by Sudhir Agrawal |
| title_short | Protocols for Oligonucleotides and Analogs |
| title_sort | protocols for oligonucleotides and analogs synthesis and properties |
| title_sub | Synthesis and Properties |
| topic | Chemistry Organic Chemistry Organic chemistry Oligonucleotide (DE-588)4133456-5 gnd Chemische Synthese (DE-588)4133806-6 gnd |
| topic_facet | Chemistry Organic Chemistry Organic chemistry Oligonucleotide Chemische Synthese |
| url | https://doi.org/10.1385/0896032817 |
| work_keys_str_mv | AT agrawalsudhir protocolsforoligonucleotidesandanalogssynthesisandproperties |