Designer Receptors Exclusively Activated by Designer Drugs:
This volume provides current methods to analyze the properties of designer receptors exclusively activated by designer drugs (DREADDs) in vitro and to measure the biological responses of DREADD activation in different neuronal populations in vivo. Chapters focus on the utility of DREADD technology t...
Gespeichert in:
Weitere Verfasser: | |
---|---|
Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
New York, NY
Springer New York
2015
|
Ausgabe: | 1st ed. 2015 |
Schriftenreihe: | Neuromethods
108 |
Schlagworte: | |
Online-Zugang: | UBR01 TUM01 URL des Erstveröffentlichers |
Zusammenfassung: | This volume provides current methods to analyze the properties of designer receptors exclusively activated by designer drugs (DREADDs) in vitro and to measure the biological responses of DREADD activation in different neuronal populations in vivo. Chapters focus on the utility of DREADD technology to selectively stimulate or inhibit neuronal activity in selected brain areas of transgenic mice. In addition, the successful use of DREADD expression in rats and Drosophila is described. Together, the DREADD technology represents a non-invasive, chemical-genetic tool for investigating neuronal signaling and the resulting behavioural responses in vivo. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory. Concise and easy-to-use, Designer Receptors Exclusively Activated by Designer Drugs aims to ensure successful results in the further study of this vital field |
Beschreibung: | 1 Online-Ressource (XVII, 160 p. 28 illus., 14 illus. in color) |
ISBN: | 9781493929443 |
DOI: | 10.1007/978-1-4939-2944-3 |
Internformat
MARC
LEADER | 00000nmm a2200000zcb4500 | ||
---|---|---|---|
001 | BV044951106 | ||
003 | DE-604 | ||
005 | 20181005 | ||
007 | cr|uuu---uuuuu | ||
008 | 180517s2015 |||| o||u| ||||||eng d | ||
020 | |a 9781493929443 |9 978-1-4939-2944-3 | ||
024 | 7 | |a 10.1007/978-1-4939-2944-3 |2 doi | |
035 | |a (ZDB-2-PRO)978-1-4939-2944-3 | ||
035 | |a (OCoLC)941394478 | ||
035 | |a (DE-599)BVBBV044951106 | ||
040 | |a DE-604 |b ger |e rda | ||
041 | 0 | |a eng | |
049 | |a DE-355 |a DE-91 | ||
082 | 0 | |a 612.8 |2 23 | |
084 | |a WE 5240 |0 (DE-625)148302: |2 rvk | ||
084 | |a WW 2200 |0 (DE-625)158906:13423 |2 rvk | ||
245 | 1 | 0 | |a Designer Receptors Exclusively Activated by Designer Drugs |c edited by Gerald Thiel |
250 | |a 1st ed. 2015 | ||
264 | 1 | |a New York, NY |b Springer New York |c 2015 | |
300 | |a 1 Online-Ressource (XVII, 160 p. 28 illus., 14 illus. in color) | ||
336 | |b txt |2 rdacontent | ||
337 | |b c |2 rdamedia | ||
338 | |b cr |2 rdacarrier | ||
490 | 0 | |a Neuromethods |v 108 | |
520 | |a This volume provides current methods to analyze the properties of designer receptors exclusively activated by designer drugs (DREADDs) in vitro and to measure the biological responses of DREADD activation in different neuronal populations in vivo. Chapters focus on the utility of DREADD technology to selectively stimulate or inhibit neuronal activity in selected brain areas of transgenic mice. In addition, the successful use of DREADD expression in rats and Drosophila is described. Together, the DREADD technology represents a non-invasive, chemical-genetic tool for investigating neuronal signaling and the resulting behavioural responses in vivo. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory. Concise and easy-to-use, Designer Receptors Exclusively Activated by Designer Drugs aims to ensure successful results in the further study of this vital field | ||
650 | 4 | |a Biomedicine | |
650 | 4 | |a Neurosciences | |
650 | 4 | |a Medicine | |
650 | 4 | |a Neurosciences | |
650 | 0 | 7 | |a G-Protein gekoppelter Rezeptor |0 (DE-588)7723480-7 |2 gnd |9 rswk-swf |
650 | 0 | 7 | |a Synthetische Droge |0 (DE-588)4217170-2 |2 gnd |9 rswk-swf |
650 | 0 | 7 | |a Ligand |g Biochemie |0 (DE-588)4606532-5 |2 gnd |9 rswk-swf |
655 | 7 | |8 1\p |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
689 | 0 | 0 | |a G-Protein gekoppelter Rezeptor |0 (DE-588)7723480-7 |D s |
689 | 0 | 1 | |a Ligand |g Biochemie |0 (DE-588)4606532-5 |D s |
689 | 0 | 2 | |a Synthetische Droge |0 (DE-588)4217170-2 |D s |
689 | 0 | |5 DE-604 | |
700 | 1 | |a Thiel, Gerald |0 (DE-588)130678775 |4 edt | |
776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781493929436 |
856 | 4 | 0 | |u https://doi.org/10.1007/978-1-4939-2944-3 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
912 | |a ZDB-2-PRO | ||
999 | |a oai:aleph.bib-bvb.de:BVB01-030343865 | ||
883 | 1 | |8 1\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
966 | e | |u https://doi.org/10.1007/978-1-4939-2944-3 |l UBR01 |p ZDB-2-PRO |x Verlag |3 Volltext | |
966 | e | |u https://doi.org/10.1007/978-1-4939-2944-3 |l TUM01 |p ZDB-2-PRO |x Verlag |3 Volltext |
Datensatz im Suchindex
_version_ | 1804178539331715072 |
---|---|
any_adam_object | |
author2 | Thiel, Gerald |
author2_role | edt |
author2_variant | g t gt |
author_GND | (DE-588)130678775 |
author_facet | Thiel, Gerald |
building | Verbundindex |
bvnumber | BV044951106 |
classification_rvk | WE 5240 WW 2200 |
collection | ZDB-2-PRO |
ctrlnum | (ZDB-2-PRO)978-1-4939-2944-3 (OCoLC)941394478 (DE-599)BVBBV044951106 |
dewey-full | 612.8 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 612 - Human physiology |
dewey-raw | 612.8 |
dewey-search | 612.8 |
dewey-sort | 3612.8 |
dewey-tens | 610 - Medicine and health |
discipline | Biologie Medizin |
doi_str_mv | 10.1007/978-1-4939-2944-3 |
edition | 1st ed. 2015 |
format | Electronic eBook |
fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03176nmm a2200565zcb4500</leader><controlfield tag="001">BV044951106</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20181005 </controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">180517s2015 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781493929443</subfield><subfield code="9">978-1-4939-2944-3</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/978-1-4939-2944-3</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-2-PRO)978-1-4939-2944-3</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)941394478</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV044951106</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield><subfield code="a">DE-91</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">612.8</subfield><subfield code="2">23</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WE 5240</subfield><subfield code="0">(DE-625)148302:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WW 2200</subfield><subfield code="0">(DE-625)158906:13423</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Designer Receptors Exclusively Activated by Designer Drugs</subfield><subfield code="c">edited by Gerald Thiel</subfield></datafield><datafield tag="250" ind1=" " ind2=" "><subfield code="a">1st ed. 2015</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">New York, NY</subfield><subfield code="b">Springer New York</subfield><subfield code="c">2015</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (XVII, 160 p. 28 illus., 14 illus. in color)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Neuromethods</subfield><subfield code="v">108</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">This volume provides current methods to analyze the properties of designer receptors exclusively activated by designer drugs (DREADDs) in vitro and to measure the biological responses of DREADD activation in different neuronal populations in vivo. Chapters focus on the utility of DREADD technology to selectively stimulate or inhibit neuronal activity in selected brain areas of transgenic mice. In addition, the successful use of DREADD expression in rats and Drosophila is described. Together, the DREADD technology represents a non-invasive, chemical-genetic tool for investigating neuronal signaling and the resulting behavioural responses in vivo. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory. Concise and easy-to-use, Designer Receptors Exclusively Activated by Designer Drugs aims to ensure successful results in the further study of this vital field</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Biomedicine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Neurosciences</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Medicine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Neurosciences</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">G-Protein gekoppelter Rezeptor</subfield><subfield code="0">(DE-588)7723480-7</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Synthetische Droge</subfield><subfield code="0">(DE-588)4217170-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Ligand</subfield><subfield code="g">Biochemie</subfield><subfield code="0">(DE-588)4606532-5</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="8">1\p</subfield><subfield code="0">(DE-588)4143413-4</subfield><subfield code="a">Aufsatzsammlung</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">G-Protein gekoppelter Rezeptor</subfield><subfield code="0">(DE-588)7723480-7</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Ligand</subfield><subfield code="g">Biochemie</subfield><subfield code="0">(DE-588)4606532-5</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="2"><subfield code="a">Synthetische Droge</subfield><subfield code="0">(DE-588)4217170-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Thiel, Gerald</subfield><subfield code="0">(DE-588)130678775</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9781493929436</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1007/978-1-4939-2944-3</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-2-PRO</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-030343865</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">1\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-1-4939-2944-3</subfield><subfield code="l">UBR01</subfield><subfield code="p">ZDB-2-PRO</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-1-4939-2944-3</subfield><subfield code="l">TUM01</subfield><subfield code="p">ZDB-2-PRO</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
genre | 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content |
genre_facet | Aufsatzsammlung |
id | DE-604.BV044951106 |
illustrated | Not Illustrated |
indexdate | 2024-07-10T08:05:35Z |
institution | BVB |
isbn | 9781493929443 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-030343865 |
oclc_num | 941394478 |
open_access_boolean | |
owner | DE-355 DE-BY-UBR DE-91 DE-BY-TUM |
owner_facet | DE-355 DE-BY-UBR DE-91 DE-BY-TUM |
physical | 1 Online-Ressource (XVII, 160 p. 28 illus., 14 illus. in color) |
psigel | ZDB-2-PRO |
publishDate | 2015 |
publishDateSearch | 2015 |
publishDateSort | 2015 |
publisher | Springer New York |
record_format | marc |
series2 | Neuromethods |
spelling | Designer Receptors Exclusively Activated by Designer Drugs edited by Gerald Thiel 1st ed. 2015 New York, NY Springer New York 2015 1 Online-Ressource (XVII, 160 p. 28 illus., 14 illus. in color) txt rdacontent c rdamedia cr rdacarrier Neuromethods 108 This volume provides current methods to analyze the properties of designer receptors exclusively activated by designer drugs (DREADDs) in vitro and to measure the biological responses of DREADD activation in different neuronal populations in vivo. Chapters focus on the utility of DREADD technology to selectively stimulate or inhibit neuronal activity in selected brain areas of transgenic mice. In addition, the successful use of DREADD expression in rats and Drosophila is described. Together, the DREADD technology represents a non-invasive, chemical-genetic tool for investigating neuronal signaling and the resulting behavioural responses in vivo. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory. Concise and easy-to-use, Designer Receptors Exclusively Activated by Designer Drugs aims to ensure successful results in the further study of this vital field Biomedicine Neurosciences Medicine G-Protein gekoppelter Rezeptor (DE-588)7723480-7 gnd rswk-swf Synthetische Droge (DE-588)4217170-2 gnd rswk-swf Ligand Biochemie (DE-588)4606532-5 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content G-Protein gekoppelter Rezeptor (DE-588)7723480-7 s Ligand Biochemie (DE-588)4606532-5 s Synthetische Droge (DE-588)4217170-2 s DE-604 Thiel, Gerald (DE-588)130678775 edt Erscheint auch als Druck-Ausgabe 9781493929436 https://doi.org/10.1007/978-1-4939-2944-3 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
spellingShingle | Designer Receptors Exclusively Activated by Designer Drugs Biomedicine Neurosciences Medicine G-Protein gekoppelter Rezeptor (DE-588)7723480-7 gnd Synthetische Droge (DE-588)4217170-2 gnd Ligand Biochemie (DE-588)4606532-5 gnd |
subject_GND | (DE-588)7723480-7 (DE-588)4217170-2 (DE-588)4606532-5 (DE-588)4143413-4 |
title | Designer Receptors Exclusively Activated by Designer Drugs |
title_auth | Designer Receptors Exclusively Activated by Designer Drugs |
title_exact_search | Designer Receptors Exclusively Activated by Designer Drugs |
title_full | Designer Receptors Exclusively Activated by Designer Drugs edited by Gerald Thiel |
title_fullStr | Designer Receptors Exclusively Activated by Designer Drugs edited by Gerald Thiel |
title_full_unstemmed | Designer Receptors Exclusively Activated by Designer Drugs edited by Gerald Thiel |
title_short | Designer Receptors Exclusively Activated by Designer Drugs |
title_sort | designer receptors exclusively activated by designer drugs |
topic | Biomedicine Neurosciences Medicine G-Protein gekoppelter Rezeptor (DE-588)7723480-7 gnd Synthetische Droge (DE-588)4217170-2 gnd Ligand Biochemie (DE-588)4606532-5 gnd |
topic_facet | Biomedicine Neurosciences Medicine G-Protein gekoppelter Rezeptor Synthetische Droge Ligand Biochemie Aufsatzsammlung |
url | https://doi.org/10.1007/978-1-4939-2944-3 |
work_keys_str_mv | AT thielgerald designerreceptorsexclusivelyactivatedbydesignerdrugs |