Cell Cycle Control and Dysregulation Protocols: Cyclins, Cyclin-Dependent Kinases, and Other Factors
The dysregulation of the normal cell cycle underlies an enormous number of pathological conditions, including the neurodegenerative disorders, all cancers, and diabetes. In Cell Cycle Control and Dysregulation Protocols: Cyclins, Cyclin-Dependent Kinases, and Other Factors, expert laboratorians deta...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2004
|
| Schriftenreihe: | Methods in Molecular Biology™
285 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 URL des Erstveröffentlichers |
| Zusammenfassung: | The dysregulation of the normal cell cycle underlies an enormous number of pathological conditions, including the neurodegenerative disorders, all cancers, and diabetes. In Cell Cycle Control and Dysregulation Protocols: Cyclins, Cyclin-Dependent Kinases, and Other Factors, expert laboratorians detail emerging methodologies for studying the cell cycle, its kinases, and kinase inhibitors. The authors focus on issues of gene expression in vivo and in vitro, the analysis of cyclin-dependent kinase inhibitors, protein degradation mediated by the proteosome, the analysis of the transformed cell phenotype, and innovative techniques to detect apoptosis. Many of the protocols are new, such as electron microsocopy to detect apoptosis and proteosome-mediated degradation, whereas others study the interactions between protein-protein, protein-DNA, and protein-RNA. The protocols follow the successful Methods in Molecular Biology™ series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. State-of-the-art and highly practical, Cell Cycle Control and Dysregulation Protocols: Cyclins, Cyclin-Dependent Kinases, and Other Factors offers pathbreaking researchers powerful tools for probing the cell cycle regulation across a wide variety of pathologies |
| Beschreibung: | 1 Online-Ressource (XIII, 185 p) |
| ISBN: | 9781592598229 |
| DOI: | 10.1385/1592598226 |
Internformat
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Datensatz im Suchindex
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| spelling | Cell Cycle Control and Dysregulation Protocols Cyclins, Cyclin-Dependent Kinases, and Other Factors edited by Antonio Giordano, Gaetano Romano Totowa, NJ Humana Press 2004 1 Online-Ressource (XIII, 185 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology™ 285 The dysregulation of the normal cell cycle underlies an enormous number of pathological conditions, including the neurodegenerative disorders, all cancers, and diabetes. In Cell Cycle Control and Dysregulation Protocols: Cyclins, Cyclin-Dependent Kinases, and Other Factors, expert laboratorians detail emerging methodologies for studying the cell cycle, its kinases, and kinase inhibitors. The authors focus on issues of gene expression in vivo and in vitro, the analysis of cyclin-dependent kinase inhibitors, protein degradation mediated by the proteosome, the analysis of the transformed cell phenotype, and innovative techniques to detect apoptosis. Many of the protocols are new, such as electron microsocopy to detect apoptosis and proteosome-mediated degradation, whereas others study the interactions between protein-protein, protein-DNA, and protein-RNA. The protocols follow the successful Methods in Molecular Biology™ series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. State-of-the-art and highly practical, Cell Cycle Control and Dysregulation Protocols: Cyclins, Cyclin-Dependent Kinases, and Other Factors offers pathbreaking researchers powerful tools for probing the cell cycle regulation across a wide variety of pathologies Biomedicine Immunology Medicine Labortechnik (DE-588)4123602-6 gnd rswk-swf Cyclin-abhängige Kinasen (DE-588)4485596-5 gnd rswk-swf Regulation (DE-588)4049075-0 gnd rswk-swf Zellzyklus (DE-588)4129960-7 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Cyclin-abhängige Kinasen (DE-588)4485596-5 s Labortechnik (DE-588)4123602-6 s DE-604 Zellzyklus (DE-588)4129960-7 s Regulation (DE-588)4049075-0 s b DE-604 Giordano, Antonio edt Romano, Gaetano edt Erscheint auch als Druck-Ausgabe 9780896039490 https://doi.org/10.1385/1592598226 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Cell Cycle Control and Dysregulation Protocols Cyclins, Cyclin-Dependent Kinases, and Other Factors Biomedicine Immunology Medicine Labortechnik (DE-588)4123602-6 gnd Cyclin-abhängige Kinasen (DE-588)4485596-5 gnd Regulation (DE-588)4049075-0 gnd Zellzyklus (DE-588)4129960-7 gnd |
| subject_GND | (DE-588)4123602-6 (DE-588)4485596-5 (DE-588)4049075-0 (DE-588)4129960-7 (DE-588)4143413-4 |
| title | Cell Cycle Control and Dysregulation Protocols Cyclins, Cyclin-Dependent Kinases, and Other Factors |
| title_auth | Cell Cycle Control and Dysregulation Protocols Cyclins, Cyclin-Dependent Kinases, and Other Factors |
| title_exact_search | Cell Cycle Control and Dysregulation Protocols Cyclins, Cyclin-Dependent Kinases, and Other Factors |
| title_full | Cell Cycle Control and Dysregulation Protocols Cyclins, Cyclin-Dependent Kinases, and Other Factors edited by Antonio Giordano, Gaetano Romano |
| title_fullStr | Cell Cycle Control and Dysregulation Protocols Cyclins, Cyclin-Dependent Kinases, and Other Factors edited by Antonio Giordano, Gaetano Romano |
| title_full_unstemmed | Cell Cycle Control and Dysregulation Protocols Cyclins, Cyclin-Dependent Kinases, and Other Factors edited by Antonio Giordano, Gaetano Romano |
| title_short | Cell Cycle Control and Dysregulation Protocols |
| title_sort | cell cycle control and dysregulation protocols cyclins cyclin dependent kinases and other factors |
| title_sub | Cyclins, Cyclin-Dependent Kinases, and Other Factors |
| topic | Biomedicine Immunology Medicine Labortechnik (DE-588)4123602-6 gnd Cyclin-abhängige Kinasen (DE-588)4485596-5 gnd Regulation (DE-588)4049075-0 gnd Zellzyklus (DE-588)4129960-7 gnd |
| topic_facet | Biomedicine Immunology Medicine Labortechnik Cyclin-abhängige Kinasen Regulation Zellzyklus Aufsatzsammlung |
| url | https://doi.org/10.1385/1592598226 |
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