Protein Lipidation Protocols:
In Protein Lipidation Protocols, Michael Gelb brings together a collection of readily reproducible techniques for studying protein lipidation, the covalent attachment of lipids to proteins. These cutting-edge methods-many never published before in a "hands-on" format-deal with glycosyl pho...
Gespeichert in:
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
1999
|
| Schriftenreihe: | Methods in Molecular Biology
116 |
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | In Protein Lipidation Protocols, Michael Gelb brings together a collection of readily reproducible techniques for studying protein lipidation, the covalent attachment of lipids to proteins. These cutting-edge methods-many never published before in a "hands-on" format-deal with glycosyl phosphatidylinositol (GPI)-containing compounds, protein fatty acylation, and protein prenylation. Included are novel techniques for determining the chemical structure of GPI-anchors, for radiolabeling the prenyl groups of protein in eukaryotic cells, a tool for developing inhibitors of the protein farnesyltransferase, and for an exciting lysosomal enzyme that cleaves fatty acyl groups from proteins, the first fatty acylase discovered. Protein Lipidation Protocols offers biochemists, cell and molecular biologists, medicinal chemists, and pharmaceutical researchers state-of-the-art tools for understanding the complex biochemistry of protein lipidation, as well as catalyzing the development of many important new biopharmaceuticals, including anticancer drugs |
| Beschreibung: | 1 Online-Ressource (X, 240 p. 35 illus) |
| ISBN: | 9781592592647 |
| DOI: | 10.1385/1592592643 |
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| 520 | |a In Protein Lipidation Protocols, Michael Gelb brings together a collection of readily reproducible techniques for studying protein lipidation, the covalent attachment of lipids to proteins. These cutting-edge methods-many never published before in a "hands-on" format-deal with glycosyl phosphatidylinositol (GPI)-containing compounds, protein fatty acylation, and protein prenylation. Included are novel techniques for determining the chemical structure of GPI-anchors, for radiolabeling the prenyl groups of protein in eukaryotic cells, a tool for developing inhibitors of the protein farnesyltransferase, and for an exciting lysosomal enzyme that cleaves fatty acyl groups from proteins, the first fatty acylase discovered. Protein Lipidation Protocols offers biochemists, cell and molecular biologists, medicinal chemists, and pharmaceutical researchers state-of-the-art tools for understanding the complex biochemistry of protein lipidation, as well as catalyzing the development of many important new biopharmaceuticals, including anticancer drugs | ||
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Datensatz im Suchindex
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| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:05:35Z |
| institution | BVB |
| isbn | 9781592592647 |
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| spelling | Protein Lipidation Protocols edited by Michael H. Gelb Totowa, NJ Humana Press 1999 1 Online-Ressource (X, 240 p. 35 illus) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 116 In Protein Lipidation Protocols, Michael Gelb brings together a collection of readily reproducible techniques for studying protein lipidation, the covalent attachment of lipids to proteins. These cutting-edge methods-many never published before in a "hands-on" format-deal with glycosyl phosphatidylinositol (GPI)-containing compounds, protein fatty acylation, and protein prenylation. Included are novel techniques for determining the chemical structure of GPI-anchors, for radiolabeling the prenyl groups of protein in eukaryotic cells, a tool for developing inhibitors of the protein farnesyltransferase, and for an exciting lysosomal enzyme that cleaves fatty acyl groups from proteins, the first fatty acylase discovered. Protein Lipidation Protocols offers biochemists, cell and molecular biologists, medicinal chemists, and pharmaceutical researchers state-of-the-art tools for understanding the complex biochemistry of protein lipidation, as well as catalyzing the development of many important new biopharmaceuticals, including anticancer drugs Life Sciences Biochemistry, general Life sciences Biochemistry Chemische Synthese (DE-588)4133806-6 gnd rswk-swf Proteine (DE-588)4076388-2 gnd rswk-swf Methode (DE-588)4038971-6 gnd rswk-swf Lipoproteide (DE-588)4074259-3 gnd rswk-swf Posttranslationale Änderung (DE-588)4204069-3 gnd rswk-swf Lipide (DE-588)4035873-2 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Lipide (DE-588)4035873-2 s Methode (DE-588)4038971-6 s DE-604 Proteine (DE-588)4076388-2 s Posttranslationale Änderung (DE-588)4204069-3 s Lipoproteide (DE-588)4074259-3 s Chemische Synthese (DE-588)4133806-6 s Gelb, Michael H. edt Erscheint auch als Druck-Ausgabe 9780896035348 https://doi.org/10.1385/1592592643 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Protein Lipidation Protocols Life Sciences Biochemistry, general Life sciences Biochemistry Chemische Synthese (DE-588)4133806-6 gnd Proteine (DE-588)4076388-2 gnd Methode (DE-588)4038971-6 gnd Lipoproteide (DE-588)4074259-3 gnd Posttranslationale Änderung (DE-588)4204069-3 gnd Lipide (DE-588)4035873-2 gnd |
| subject_GND | (DE-588)4133806-6 (DE-588)4076388-2 (DE-588)4038971-6 (DE-588)4074259-3 (DE-588)4204069-3 (DE-588)4035873-2 (DE-588)4143413-4 |
| title | Protein Lipidation Protocols |
| title_auth | Protein Lipidation Protocols |
| title_exact_search | Protein Lipidation Protocols |
| title_full | Protein Lipidation Protocols edited by Michael H. Gelb |
| title_fullStr | Protein Lipidation Protocols edited by Michael H. Gelb |
| title_full_unstemmed | Protein Lipidation Protocols edited by Michael H. Gelb |
| title_short | Protein Lipidation Protocols |
| title_sort | protein lipidation protocols |
| topic | Life Sciences Biochemistry, general Life sciences Biochemistry Chemische Synthese (DE-588)4133806-6 gnd Proteine (DE-588)4076388-2 gnd Methode (DE-588)4038971-6 gnd Lipoproteide (DE-588)4074259-3 gnd Posttranslationale Änderung (DE-588)4204069-3 gnd Lipide (DE-588)4035873-2 gnd |
| topic_facet | Life Sciences Biochemistry, general Life sciences Biochemistry Chemische Synthese Proteine Methode Lipoproteide Posttranslationale Änderung Lipide Aufsatzsammlung |
| url | https://doi.org/10.1385/1592592643 |
| work_keys_str_mv | AT gelbmichaelh proteinlipidationprotocols |