Interleukin Protocols:
Interleukins, a family of proteins that regulate immunity and inflammation throughout the body, are also involved in autoimmune disease (rheumatoid arthritis, multiple sclerosis, and asthma); are implicated in such other conditions as cancer, myocardial infarction, and depression; and have value in...
Gespeichert in:
Weitere Verfasser: | , |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Totowa, NJ
Springer New York
2001
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Schriftenreihe: | Methods in Molecular Medicine™
60 |
Schlagworte: | |
Online-Zugang: | UBR01 TUM01 Volltext |
Zusammenfassung: | Interleukins, a family of proteins that regulate immunity and inflammation throughout the body, are also involved in autoimmune disease (rheumatoid arthritis, multiple sclerosis, and asthma); are implicated in such other conditions as cancer, myocardial infarction, and depression; and have value in the diagnosis and prognosis of many diseases. Luke O'Neill and Andrew Bowie bring together in Interleukin Protocols a collection of standard and advanced methods for measuring these powerful agents. Their readily reproducible techniques range from the assay of interleukin protein and mRNA-using ELISA, FACS, and RT-PCR-to the study of interleukin signal transduction. Newer techniques are also covered, including the analysis of interleukin gene polymorphisms and the use of cDNA microarrays. Many of the assays are geared to specific pathologies, including breast cancer, depression, psoriasis, Grave's disease, migraine, and myocardial infarction. There are also helpful discussions of the difficulties in measuring interleukins in different biological fluids, such as sputum from asthma patients, peritoneal fluids, synovial fluid from arthritic joints, and cerbrospinal fluid from patients with meningitis. Each step-by-step method is described by a hands-on expert and includes notes on how to avoid failure. Comprehensive and highly practical, Interleukin Protocols offers biomedical investigators a stellar collection of all the major techniques needed to analyze the role of interleukins in disease, to improve diagnosis, and to foster the rapid emergence of new and more powerful therapeutics |
Beschreibung: | 1 Online-Ressource (XV, 443 p) |
ISBN: | 9781592591466 |
DOI: | 10.1385/1592591469 |
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520 | |a Interleukins, a family of proteins that regulate immunity and inflammation throughout the body, are also involved in autoimmune disease (rheumatoid arthritis, multiple sclerosis, and asthma); are implicated in such other conditions as cancer, myocardial infarction, and depression; and have value in the diagnosis and prognosis of many diseases. Luke O'Neill and Andrew Bowie bring together in Interleukin Protocols a collection of standard and advanced methods for measuring these powerful agents. Their readily reproducible techniques range from the assay of interleukin protein and mRNA-using ELISA, FACS, and RT-PCR-to the study of interleukin signal transduction. Newer techniques are also covered, including the analysis of interleukin gene polymorphisms and the use of cDNA microarrays. Many of the assays are geared to specific pathologies, including breast cancer, depression, psoriasis, Grave's disease, migraine, and myocardial infarction. There are also helpful discussions of the difficulties in measuring interleukins in different biological fluids, such as sputum from asthma patients, peritoneal fluids, synovial fluid from arthritic joints, and cerbrospinal fluid from patients with meningitis. Each step-by-step method is described by a hands-on expert and includes notes on how to avoid failure. Comprehensive and highly practical, Interleukin Protocols offers biomedical investigators a stellar collection of all the major techniques needed to analyze the role of interleukins in disease, to improve diagnosis, and to foster the rapid emergence of new and more powerful therapeutics | ||
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Datensatz im Suchindex
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any_adam_object | |
author2 | O’Neill, Luke A. J. Bowie, Andrew |
author2_role | edt edt |
author2_variant | l a j o laj lajo a b ab |
author_facet | O’Neill, Luke A. J. Bowie, Andrew |
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dewey-full | 616.079 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 616 - Diseases |
dewey-raw | 616.079 |
dewey-search | 616.079 |
dewey-sort | 3616.079 |
dewey-tens | 610 - Medicine and health |
discipline | Medizin |
doi_str_mv | 10.1385/1592591469 |
format | Electronic eBook |
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indexdate | 2024-07-10T08:05:34Z |
institution | BVB |
isbn | 9781592591466 |
language | English |
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series2 | Methods in Molecular Medicine™ |
spelling | Interleukin Protocols edited by Luke A. J. O’Neill, Andrew Bowie Totowa, NJ Springer New York 2001 1 Online-Ressource (XV, 443 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Medicine™ 60 Interleukins, a family of proteins that regulate immunity and inflammation throughout the body, are also involved in autoimmune disease (rheumatoid arthritis, multiple sclerosis, and asthma); are implicated in such other conditions as cancer, myocardial infarction, and depression; and have value in the diagnosis and prognosis of many diseases. Luke O'Neill and Andrew Bowie bring together in Interleukin Protocols a collection of standard and advanced methods for measuring these powerful agents. Their readily reproducible techniques range from the assay of interleukin protein and mRNA-using ELISA, FACS, and RT-PCR-to the study of interleukin signal transduction. Newer techniques are also covered, including the analysis of interleukin gene polymorphisms and the use of cDNA microarrays. Many of the assays are geared to specific pathologies, including breast cancer, depression, psoriasis, Grave's disease, migraine, and myocardial infarction. There are also helpful discussions of the difficulties in measuring interleukins in different biological fluids, such as sputum from asthma patients, peritoneal fluids, synovial fluid from arthritic joints, and cerbrospinal fluid from patients with meningitis. Each step-by-step method is described by a hands-on expert and includes notes on how to avoid failure. Comprehensive and highly practical, Interleukin Protocols offers biomedical investigators a stellar collection of all the major techniques needed to analyze the role of interleukins in disease, to improve diagnosis, and to foster the rapid emergence of new and more powerful therapeutics Biomedicine Immunology Medicine O’Neill, Luke A. J. edt Bowie, Andrew edt Erscheint auch als Druck-Ausgabe 9780896037380 https://doi.org/10.1385/1592591469 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Interleukin Protocols Biomedicine Immunology Medicine |
title | Interleukin Protocols |
title_auth | Interleukin Protocols |
title_exact_search | Interleukin Protocols |
title_full | Interleukin Protocols edited by Luke A. J. O’Neill, Andrew Bowie |
title_fullStr | Interleukin Protocols edited by Luke A. J. O’Neill, Andrew Bowie |
title_full_unstemmed | Interleukin Protocols edited by Luke A. J. O’Neill, Andrew Bowie |
title_short | Interleukin Protocols |
title_sort | interleukin protocols |
topic | Biomedicine Immunology Medicine |
topic_facet | Biomedicine Immunology Medicine |
url | https://doi.org/10.1385/1592591469 |
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