Monoclonal Antibodies: Methods and Protocols
Monoclonal Antibodies: Methods and Protocols examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting with opening chapters focusing on the gold standard method for generating mouse monoclonal antibodies through hybridoma technology, future methods fo...
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2007
|
| Schriftenreihe: | Methods in Molecular Biology
378 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | Monoclonal Antibodies: Methods and Protocols examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting with opening chapters focusing on the gold standard method for generating mouse monoclonal antibodies through hybridoma technology, future methods for engineering recombinant and humanized antibodies, methods for engineering soluble Fc fusion protein, and the use of antibodies and flow cytometry in the quantification of cell signaling proteins. Specific chapters describe how antibodies are used for the diagnosis and classification of hematologic diseases. Subsequent chapters examine the advantages and most recent advances of using bead-based immunoassays, including the ability of bead-based technology to multiplex and analyze several analytes simultaneously, and the use of beads in detecting fusion proteins resulting from chromosomal translocations. Concluding chapters provide additional examples of methodologies that employ monoclonal antibodies. Monoclonal Antibodies: Methods and Protocols provides descriptions of methods that cover a wide spectrum of applications in the field of monoclonal antibodies. This field will continue to expand and provide new and innovative techniques, not only in the laboratory, but also as a basis that complements targeted therapy |
| Beschreibung: | 1 Online-Ressource (XII, 228 p. 75 illus., 4 illus. in color) |
| ISBN: | 9781597453233 |
| DOI: | 10.1007/978-1-59745-323-3 |
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| indexdate | 2024-07-10T08:05:34Z |
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| isbn | 9781597453233 |
| language | English |
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| spelling | Monoclonal Antibodies Methods and Protocols edited by Maher Albitar Totowa, NJ Humana Press 2007 1 Online-Ressource (XII, 228 p. 75 illus., 4 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 378 Monoclonal Antibodies: Methods and Protocols examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting with opening chapters focusing on the gold standard method for generating mouse monoclonal antibodies through hybridoma technology, future methods for engineering recombinant and humanized antibodies, methods for engineering soluble Fc fusion protein, and the use of antibodies and flow cytometry in the quantification of cell signaling proteins. Specific chapters describe how antibodies are used for the diagnosis and classification of hematologic diseases. Subsequent chapters examine the advantages and most recent advances of using bead-based immunoassays, including the ability of bead-based technology to multiplex and analyze several analytes simultaneously, and the use of beads in detecting fusion proteins resulting from chromosomal translocations. Concluding chapters provide additional examples of methodologies that employ monoclonal antibodies. Monoclonal Antibodies: Methods and Protocols provides descriptions of methods that cover a wide spectrum of applications in the field of monoclonal antibodies. This field will continue to expand and provide new and innovative techniques, not only in the laboratory, but also as a basis that complements targeted therapy Biomedicine Immunology Cancer Research Molecular Medicine Medicine Cancer research Molecular biology Albitar, Maher edt Erscheint auch als Druck-Ausgabe 9781588295675 https://doi.org/10.1007/978-1-59745-323-3 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Monoclonal Antibodies Methods and Protocols Biomedicine Immunology Cancer Research Molecular Medicine Medicine Cancer research Molecular biology |
| title | Monoclonal Antibodies Methods and Protocols |
| title_auth | Monoclonal Antibodies Methods and Protocols |
| title_exact_search | Monoclonal Antibodies Methods and Protocols |
| title_full | Monoclonal Antibodies Methods and Protocols edited by Maher Albitar |
| title_fullStr | Monoclonal Antibodies Methods and Protocols edited by Maher Albitar |
| title_full_unstemmed | Monoclonal Antibodies Methods and Protocols edited by Maher Albitar |
| title_short | Monoclonal Antibodies |
| title_sort | monoclonal antibodies methods and protocols |
| title_sub | Methods and Protocols |
| topic | Biomedicine Immunology Cancer Research Molecular Medicine Medicine Cancer research Molecular biology |
| topic_facet | Biomedicine Immunology Cancer Research Molecular Medicine Medicine Cancer research Molecular biology |
| url | https://doi.org/10.1007/978-1-59745-323-3 |
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