Cartilage and Osteoarthritis: Volume 1: Cellular and Molecular Tools
Osteoarthritis, the most common form of arthritis, imposes a significant burden of suffering on a growing population of the elderly. Even today, its poorly understood pathophysiology limits the discovery of molecular targets for pharmacological intervention and there are few effective medical treatm...
Gespeichert in:
| Weitere Verfasser: | , , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2004
|
| Schriftenreihe: | Methods in Molecular Medicine™
100 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | Osteoarthritis, the most common form of arthritis, imposes a significant burden of suffering on a growing population of the elderly. Even today, its poorly understood pathophysiology limits the discovery of molecular targets for pharmacological intervention and there are few effective medical treatments beyond pain control and surgery. In Cartilage and Osteoarthritis a distinguished panel of researchers, physicians, and opinion leaders in this challenging field describe their updated classical, but still evolving, techniques, as well as many emerging methods that promise to add significantly to our understanding of cartilage metabolism in health and disease. Volume 1: Cellular and Molecular Tools describes proven molecular and cellular techniques for the in vitro study of normal and osteoarthritic cartilage through biochemical, biomolecular, immunological, and physical approaches, with emphasis on the genetic manipulation of cells. The protocols follow the successful Methods in Molecular Medicine™ series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. A companion volume, Volume 2: Structure and In Vivo Analysis, offers cutting-edge procedures for studies-at the tissue level-of turnover, structure, and functioning in normal and diseased cartilage by invasive and noninvasive means. Comprehensive and up-to-date, the two volumes of Cartilage and Osteoarthritis provide researchers and bench scientists alike with an indispensable collection of readily reproducible protocols for new experiments-from the cellular to the animal level-designed to more clearly describe the pathophysiology of cartilage, as well as to discover novel molecular targets for pharmacological intervention |
| Beschreibung: | 1 Online-Ressource (XIV, 358 p) |
| ISBN: | 9781592598106 |
| DOI: | 10.1385/1592598102 |
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| 520 | |a Osteoarthritis, the most common form of arthritis, imposes a significant burden of suffering on a growing population of the elderly. Even today, its poorly understood pathophysiology limits the discovery of molecular targets for pharmacological intervention and there are few effective medical treatments beyond pain control and surgery. In Cartilage and Osteoarthritis a distinguished panel of researchers, physicians, and opinion leaders in this challenging field describe their updated classical, but still evolving, techniques, as well as many emerging methods that promise to add significantly to our understanding of cartilage metabolism in health and disease. Volume 1: Cellular and Molecular Tools describes proven molecular and cellular techniques for the in vitro study of normal and osteoarthritic cartilage through biochemical, biomolecular, immunological, and physical approaches, with emphasis on the genetic manipulation of cells. The protocols follow the successful Methods in Molecular Medicine™ series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. A companion volume, Volume 2: Structure and In Vivo Analysis, offers cutting-edge procedures for studies-at the tissue level-of turnover, structure, and functioning in normal and diseased cartilage by invasive and noninvasive means. Comprehensive and up-to-date, the two volumes of Cartilage and Osteoarthritis provide researchers and bench scientists alike with an indispensable collection of readily reproducible protocols for new experiments-from the cellular to the animal level-designed to more clearly describe the pathophysiology of cartilage, as well as to discover novel molecular targets for pharmacological intervention | ||
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| discipline | Medizin |
| doi_str_mv | 10.1385/1592598102 |
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| spelling | Cartilage and Osteoarthritis Volume 1: Cellular and Molecular Tools edited by Massimo Sabatini, Philippe Pastoureau, Frédéric De Ceuninck Totowa, NJ Humana Press 2004 1 Online-Ressource (XIV, 358 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Medicine™ 100 Osteoarthritis, the most common form of arthritis, imposes a significant burden of suffering on a growing population of the elderly. Even today, its poorly understood pathophysiology limits the discovery of molecular targets for pharmacological intervention and there are few effective medical treatments beyond pain control and surgery. In Cartilage and Osteoarthritis a distinguished panel of researchers, physicians, and opinion leaders in this challenging field describe their updated classical, but still evolving, techniques, as well as many emerging methods that promise to add significantly to our understanding of cartilage metabolism in health and disease. Volume 1: Cellular and Molecular Tools describes proven molecular and cellular techniques for the in vitro study of normal and osteoarthritic cartilage through biochemical, biomolecular, immunological, and physical approaches, with emphasis on the genetic manipulation of cells. The protocols follow the successful Methods in Molecular Medicine™ series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. A companion volume, Volume 2: Structure and In Vivo Analysis, offers cutting-edge procedures for studies-at the tissue level-of turnover, structure, and functioning in normal and diseased cartilage by invasive and noninvasive means. Comprehensive and up-to-date, the two volumes of Cartilage and Osteoarthritis provide researchers and bench scientists alike with an indispensable collection of readily reproducible protocols for new experiments-from the cellular to the animal level-designed to more clearly describe the pathophysiology of cartilage, as well as to discover novel molecular targets for pharmacological intervention Medicine & Public Health Endocrinology Medicine Sabatini, Massimo edt Pastoureau, Philippe edt Ceuninck, Frédéric De edt Erscheint auch als Druck-Ausgabe 9781588292476 https://doi.org/10.1385/1592598102 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Cartilage and Osteoarthritis Volume 1: Cellular and Molecular Tools Medicine & Public Health Endocrinology Medicine |
| title | Cartilage and Osteoarthritis Volume 1: Cellular and Molecular Tools |
| title_auth | Cartilage and Osteoarthritis Volume 1: Cellular and Molecular Tools |
| title_exact_search | Cartilage and Osteoarthritis Volume 1: Cellular and Molecular Tools |
| title_full | Cartilage and Osteoarthritis Volume 1: Cellular and Molecular Tools edited by Massimo Sabatini, Philippe Pastoureau, Frédéric De Ceuninck |
| title_fullStr | Cartilage and Osteoarthritis Volume 1: Cellular and Molecular Tools edited by Massimo Sabatini, Philippe Pastoureau, Frédéric De Ceuninck |
| title_full_unstemmed | Cartilage and Osteoarthritis Volume 1: Cellular and Molecular Tools edited by Massimo Sabatini, Philippe Pastoureau, Frédéric De Ceuninck |
| title_short | Cartilage and Osteoarthritis |
| title_sort | cartilage and osteoarthritis volume 1 cellular and molecular tools |
| title_sub | Volume 1: Cellular and Molecular Tools |
| topic | Medicine & Public Health Endocrinology Medicine |
| topic_facet | Medicine & Public Health Endocrinology Medicine |
| url | https://doi.org/10.1385/1592598102 |
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