Cardiovascular Proteomics: Methods and Protocols
Over the past few years, the power and potential of proteomics has become widely recognized. The use of proteomics for the study of complex diseases is increasing and is particularly applicable to cardiovascular disease, the leading cause of death in developed countries. The ability to investigate t...
Gespeichert in:
| Weitere Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2007
|
| Schriftenreihe: | Methods in Molecular Biology™
357 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | Over the past few years, the power and potential of proteomics has become widely recognized. The use of proteomics for the study of complex diseases is increasing and is particularly applicable to cardiovascular disease, the leading cause of death in developed countries. The ability to investigate the complete proteome provides a critical tool toward elucidating the complex and multif- torial basis of cardiovascular biology, especially disease processes. Proteomics involves the integration of a number of technologies with the aim of analyzing all the proteins expressed by a biological system in response to various stimuli under different pathophysiological conditions. The proteomic approach offers the ability to evaluate simultaneously the changes in protein expression and cell signaling pathways in response to such conditions as atherosclerosis, c- diac hypertrophy, stroke, or heart failure. Cardiovascular Proteomics: Methods and Protocols covers many of the above aspects of the proteomic approach in the cardiovascular field. This v- ume takes the reader through the complete process of proteomic analysis, from the obtention of specific heart proteins (troponin I) to the new techniques of identifying risk biomarkers of atherome plaque rupture, analyzing the secretome of explanted endarterectomies cultured in vitro, or the application of phage display techniques to decipher the molecular diversity of blood vessels |
| Beschreibung: | 1 Online-Ressource (432 p. 134 illus., 6 illus. in color) |
| ISBN: | 9781597452144 |
| DOI: | 10.1385/1597452149 |
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| 520 | |a Over the past few years, the power and potential of proteomics has become widely recognized. The use of proteomics for the study of complex diseases is increasing and is particularly applicable to cardiovascular disease, the leading cause of death in developed countries. The ability to investigate the complete proteome provides a critical tool toward elucidating the complex and multif- torial basis of cardiovascular biology, especially disease processes. Proteomics involves the integration of a number of technologies with the aim of analyzing all the proteins expressed by a biological system in response to various stimuli under different pathophysiological conditions. The proteomic approach offers the ability to evaluate simultaneously the changes in protein expression and cell signaling pathways in response to such conditions as atherosclerosis, c- diac hypertrophy, stroke, or heart failure. Cardiovascular Proteomics: Methods and Protocols covers many of the above aspects of the proteomic approach in the cardiovascular field. This v- ume takes the reader through the complete process of proteomic analysis, from the obtention of specific heart proteins (troponin I) to the new techniques of identifying risk biomarkers of atherome plaque rupture, analyzing the secretome of explanted endarterectomies cultured in vitro, or the application of phage display techniques to decipher the molecular diversity of blood vessels | ||
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| discipline | Biologie Medizin |
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| id | DE-604.BV044950888 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:05:34Z |
| institution | BVB |
| isbn | 9781597452144 |
| language | English |
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| spelling | Cardiovascular Proteomics Methods and Protocols edited by Fernando Vivanco Totowa, NJ Humana Press 2007 1 Online-Ressource (432 p. 134 illus., 6 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology™ 357 Over the past few years, the power and potential of proteomics has become widely recognized. The use of proteomics for the study of complex diseases is increasing and is particularly applicable to cardiovascular disease, the leading cause of death in developed countries. The ability to investigate the complete proteome provides a critical tool toward elucidating the complex and multif- torial basis of cardiovascular biology, especially disease processes. Proteomics involves the integration of a number of technologies with the aim of analyzing all the proteins expressed by a biological system in response to various stimuli under different pathophysiological conditions. The proteomic approach offers the ability to evaluate simultaneously the changes in protein expression and cell signaling pathways in response to such conditions as atherosclerosis, c- diac hypertrophy, stroke, or heart failure. Cardiovascular Proteomics: Methods and Protocols covers many of the above aspects of the proteomic approach in the cardiovascular field. This v- ume takes the reader through the complete process of proteomic analysis, from the obtention of specific heart proteins (troponin I) to the new techniques of identifying risk biomarkers of atherome plaque rupture, analyzing the secretome of explanted endarterectomies cultured in vitro, or the application of phage display techniques to decipher the molecular diversity of blood vessels Life Sciences Biochemistry, general Cell Biology Life sciences Biochemistry Cell biology Vivanco, Fernando edt Erscheint auch als Druck-Ausgabe 9781588295354 https://doi.org/10.1385/1597452149 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Cardiovascular Proteomics Methods and Protocols Life Sciences Biochemistry, general Cell Biology Life sciences Biochemistry Cell biology |
| title | Cardiovascular Proteomics Methods and Protocols |
| title_auth | Cardiovascular Proteomics Methods and Protocols |
| title_exact_search | Cardiovascular Proteomics Methods and Protocols |
| title_full | Cardiovascular Proteomics Methods and Protocols edited by Fernando Vivanco |
| title_fullStr | Cardiovascular Proteomics Methods and Protocols edited by Fernando Vivanco |
| title_full_unstemmed | Cardiovascular Proteomics Methods and Protocols edited by Fernando Vivanco |
| title_short | Cardiovascular Proteomics |
| title_sort | cardiovascular proteomics methods and protocols |
| title_sub | Methods and Protocols |
| topic | Life Sciences Biochemistry, general Cell Biology Life sciences Biochemistry Cell biology |
| topic_facet | Life Sciences Biochemistry, general Cell Biology Life sciences Biochemistry Cell biology |
| url | https://doi.org/10.1385/1597452149 |
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