Mitochondrial DNA: Methods and Protocols
Since the publication of the first edition, the number of unique heritable mtDNA mutations recognized as being associated with bioenergetic dysfunction, cell death and disease has grown. Likewise, our understanding of the basic biology of somatic mtDNA mutations continues to improve. In Mitochondria...
Gespeichert in:
| Weitere Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2009
|
| Ausgabe: | 2 |
| Schriftenreihe: | Methods in Molecular Biology™
554 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | Since the publication of the first edition, the number of unique heritable mtDNA mutations recognized as being associated with bioenergetic dysfunction, cell death and disease has grown. Likewise, our understanding of the basic biology of somatic mtDNA mutations continues to improve. In Mitochondrial DNA: Methods and Protocols, Second Edition, specialists from eight countries share their expertise, providing detailed protocols for studying many aspects of mtDNA. The volume is divided into three sections, which cover the transduction of information from mtDNA to functionally active respiratory complexes, mitochondrial reactive oxygen species (ROS) production as well as mtDNA damage and its repair, and the identification and quantification of heteroplasmic mtDNA mutations. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes sections, highlighting tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Mitrochondrial DNA: Methods and Protocols, Second Edition promises to aid researchers in further expanding our knowledge of this vital area of cell biology |
| Beschreibung: | 1 Online-Ressource (XII, 404 p. 74 illus., 1 illus. in color) |
| ISBN: | 9781597455213 |
| DOI: | 10.1007/978-1-59745-521-3 |
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| spelling | Mitochondrial DNA Methods and Protocols edited by Jeffrey A. Stuart 2 Totowa, NJ Humana Press 2009 1 Online-Ressource (XII, 404 p. 74 illus., 1 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology™ 554 Since the publication of the first edition, the number of unique heritable mtDNA mutations recognized as being associated with bioenergetic dysfunction, cell death and disease has grown. Likewise, our understanding of the basic biology of somatic mtDNA mutations continues to improve. In Mitochondrial DNA: Methods and Protocols, Second Edition, specialists from eight countries share their expertise, providing detailed protocols for studying many aspects of mtDNA. The volume is divided into three sections, which cover the transduction of information from mtDNA to functionally active respiratory complexes, mitochondrial reactive oxygen species (ROS) production as well as mtDNA damage and its repair, and the identification and quantification of heteroplasmic mtDNA mutations. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes sections, highlighting tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Mitrochondrial DNA: Methods and Protocols, Second Edition promises to aid researchers in further expanding our knowledge of this vital area of cell biology Life Sciences Cell Biology Human Genetics Life sciences Human genetics Cell biology Mitochondriale DNS (DE-588)4202301-4 gnd rswk-swf Methode (DE-588)4038971-6 gnd rswk-swf Mitochondriale DNS (DE-588)4202301-4 s Methode (DE-588)4038971-6 s b DE-604 Stuart, Jeffrey A. edt Erscheint auch als Druck-Ausgabe 9781934115602 https://doi.org/10.1007/978-1-59745-521-3 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Mitochondrial DNA Methods and Protocols Life Sciences Cell Biology Human Genetics Life sciences Human genetics Cell biology Mitochondriale DNS (DE-588)4202301-4 gnd Methode (DE-588)4038971-6 gnd |
| subject_GND | (DE-588)4202301-4 (DE-588)4038971-6 |
| title | Mitochondrial DNA Methods and Protocols |
| title_auth | Mitochondrial DNA Methods and Protocols |
| title_exact_search | Mitochondrial DNA Methods and Protocols |
| title_full | Mitochondrial DNA Methods and Protocols edited by Jeffrey A. Stuart |
| title_fullStr | Mitochondrial DNA Methods and Protocols edited by Jeffrey A. Stuart |
| title_full_unstemmed | Mitochondrial DNA Methods and Protocols edited by Jeffrey A. Stuart |
| title_short | Mitochondrial DNA |
| title_sort | mitochondrial dna methods and protocols |
| title_sub | Methods and Protocols |
| topic | Life Sciences Cell Biology Human Genetics Life sciences Human genetics Cell biology Mitochondriale DNS (DE-588)4202301-4 gnd Methode (DE-588)4038971-6 gnd |
| topic_facet | Life Sciences Cell Biology Human Genetics Life sciences Human genetics Cell biology Mitochondriale DNS Methode |
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