Proteases and Cancer: Methods and Protocols
Proteases decisively contribute to cancer development and promotion by regulating the activities of growth factors/cytokines and signaling receptors, as well as the composition of the extracellular matrix, thereby suppressing cell death pathways and activating cell survival pathways. In Proteases an...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2009
|
| Schriftenreihe: | Methods in Molecular Biology™, Methods and Protocols
539 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | Proteases decisively contribute to cancer development and promotion by regulating the activities of growth factors/cytokines and signaling receptors, as well as the composition of the extracellular matrix, thereby suppressing cell death pathways and activating cell survival pathways. In Proteases and Cancer: Methods and Protocols, expert researchers bring together a wide range of current, complimentary techniques that have been developed for the specific detection and analysis of proteases and their activities in cancer biology. The volume covers vital topics including the application of proteomics technologies for the detection of protease expression in tumors, imaging proteases by activity profiling, proteomics technologies for the identification of biological substrates, detection of cell surface proteolysis, imaging of protease activity, the use of transgenic mice to determine protease function in tumor initiation and progression, and the development of anti-protease therapies for cancer. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easy to use, Proteases and Cancer: Methods and Protocols is an ideal guide for scientists who wish to pursue the study of this important branch of cancer research and the development of unique innovative technologies to aid in that study |
| Beschreibung: | 1 Online-Ressource (XII, 221 p) |
| ISBN: | 9781603270038 |
| DOI: | 10.1007/978-1-60327-003-8 |
Internformat
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Datensatz im Suchindex
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| author2 | Bugge, Thomas H. Antalis, Toni M. |
| author2_role | edt edt |
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| author_facet | Bugge, Thomas H. Antalis, Toni M. |
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| ctrlnum | (ZDB-2-PRO)978-1-60327-003-8 (OCoLC)712419283 (DE-599)BVBBV044950845 |
| dewey-full | 614.5999 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 614 - Forensic medicine; incidence of disease |
| dewey-raw | 614.5999 |
| dewey-search | 614.5999 |
| dewey-sort | 3614.5999 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1007/978-1-60327-003-8 |
| format | Electronic eBook |
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| spelling | Proteases and Cancer Methods and Protocols edited by Thomas H. Bugge, Toni M. Antalis Totowa, NJ Humana Press 2009 1 Online-Ressource (XII, 221 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology™, Methods and Protocols 539 Proteases decisively contribute to cancer development and promotion by regulating the activities of growth factors/cytokines and signaling receptors, as well as the composition of the extracellular matrix, thereby suppressing cell death pathways and activating cell survival pathways. In Proteases and Cancer: Methods and Protocols, expert researchers bring together a wide range of current, complimentary techniques that have been developed for the specific detection and analysis of proteases and their activities in cancer biology. The volume covers vital topics including the application of proteomics technologies for the detection of protease expression in tumors, imaging proteases by activity profiling, proteomics technologies for the identification of biological substrates, detection of cell surface proteolysis, imaging of protease activity, the use of transgenic mice to determine protease function in tumor initiation and progression, and the development of anti-protease therapies for cancer. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easy to use, Proteases and Cancer: Methods and Protocols is an ideal guide for scientists who wish to pursue the study of this important branch of cancer research and the development of unique innovative technologies to aid in that study Biomedicine Cancer Research Enzymology Medicine Cancer research Proteasen (DE-588)4047521-9 gnd rswk-swf Molekularpathologie (DE-588)4170396-0 gnd rswk-swf Krebs Medizin (DE-588)4073781-0 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Krebs Medizin (DE-588)4073781-0 s Proteasen (DE-588)4047521-9 s Molekularpathologie (DE-588)4170396-0 s 2\p DE-604 Bugge, Thomas H. edt Antalis, Toni M. edt Erscheint auch als Druck-Ausgabe 9781603270021 https://doi.org/10.1007/978-1-60327-003-8 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Proteases and Cancer Methods and Protocols Biomedicine Cancer Research Enzymology Medicine Cancer research Proteasen (DE-588)4047521-9 gnd Molekularpathologie (DE-588)4170396-0 gnd Krebs Medizin (DE-588)4073781-0 gnd |
| subject_GND | (DE-588)4047521-9 (DE-588)4170396-0 (DE-588)4073781-0 (DE-588)4143413-4 |
| title | Proteases and Cancer Methods and Protocols |
| title_auth | Proteases and Cancer Methods and Protocols |
| title_exact_search | Proteases and Cancer Methods and Protocols |
| title_full | Proteases and Cancer Methods and Protocols edited by Thomas H. Bugge, Toni M. Antalis |
| title_fullStr | Proteases and Cancer Methods and Protocols edited by Thomas H. Bugge, Toni M. Antalis |
| title_full_unstemmed | Proteases and Cancer Methods and Protocols edited by Thomas H. Bugge, Toni M. Antalis |
| title_short | Proteases and Cancer |
| title_sort | proteases and cancer methods and protocols |
| title_sub | Methods and Protocols |
| topic | Biomedicine Cancer Research Enzymology Medicine Cancer research Proteasen (DE-588)4047521-9 gnd Molekularpathologie (DE-588)4170396-0 gnd Krebs Medizin (DE-588)4073781-0 gnd |
| topic_facet | Biomedicine Cancer Research Enzymology Medicine Cancer research Proteasen Molekularpathologie Krebs Medizin Aufsatzsammlung |
| url | https://doi.org/10.1007/978-1-60327-003-8 |
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