Amyloid Proteins: Methods and Protocols
In recent years, various in vitro and in vivo techniques, transgenic technologies, and novel animal models have been developed to understand amyloid diseases-such as Alzheimer's disease and some forms of diabetes-and to screen for drugs that can block amyloid formation and/or disassemble its as...
Gespeichert in:
| Weitere Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2005
|
| Schriftenreihe: | Methods in Molecular Biology™
299 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | In recent years, various in vitro and in vivo techniques, transgenic technologies, and novel animal models have been developed to understand amyloid diseases-such as Alzheimer's disease and some forms of diabetes-and to screen for drugs that can block amyloid formation and/or disassemble its associated fibrils. In Amyloid Proteins: Methods and Protocols, internationally known researchers describe in step-by-step detail their best techniques for studying these types of proteins and their involvement in the etiology, pathogenesis, diagnosis, and therapy of amyloid diseases. The contributors provide proven methods for the preparation of amyloid and its precursors (oligomers and protofibrils), in vitro assays and analytical techniques for their study, and cell culture models and assays for the production of amyloid proteins. Additional chapters present readily reproducible techniques for amyloid extraction from tissue, its detection in vitro and in vivo, as well as nontransgenic methods for developing amyloid mouse models. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Authoritative and highly practical, Amyloid Proteins: Methods and Protocols offers both skilled and novice investigators a proven collection of standard and novel techniques for studying amyloid proteins and peptides, as well as their relation to amyloid diseases |
| Beschreibung: | 1 Online-Ressource (408 p. 156 illus., 1 illus. in color) |
| ISBN: | 9781592598748 |
| DOI: | 10.1385/1592598749 |
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| spelling | Amyloid Proteins Methods and Protocols edited by Einar M. Sigurdsson Totowa, NJ Humana Press 2005 1 Online-Ressource (408 p. 156 illus., 1 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology™ 299 In recent years, various in vitro and in vivo techniques, transgenic technologies, and novel animal models have been developed to understand amyloid diseases-such as Alzheimer's disease and some forms of diabetes-and to screen for drugs that can block amyloid formation and/or disassemble its associated fibrils. In Amyloid Proteins: Methods and Protocols, internationally known researchers describe in step-by-step detail their best techniques for studying these types of proteins and their involvement in the etiology, pathogenesis, diagnosis, and therapy of amyloid diseases. The contributors provide proven methods for the preparation of amyloid and its precursors (oligomers and protofibrils), in vitro assays and analytical techniques for their study, and cell culture models and assays for the production of amyloid proteins. Additional chapters present readily reproducible techniques for amyloid extraction from tissue, its detection in vitro and in vivo, as well as nontransgenic methods for developing amyloid mouse models. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Authoritative and highly practical, Amyloid Proteins: Methods and Protocols offers both skilled and novice investigators a proven collection of standard and novel techniques for studying amyloid proteins and peptides, as well as their relation to amyloid diseases Life Sciences Biochemistry, general Life sciences Biochemistry Amyloid beta- (DE-588)4385528-3 gnd rswk-swf Proteine (DE-588)4076388-2 gnd rswk-swf Labortechnik (DE-588)4123602-6 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Proteine (DE-588)4076388-2 s Amyloid beta- (DE-588)4385528-3 s Labortechnik (DE-588)4123602-6 s b DE-604 Sigurdsson, Einar M. edt Erscheint auch als Druck-Ausgabe 9781588293374 https://doi.org/10.1385/1592598749 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Amyloid Proteins Methods and Protocols Life Sciences Biochemistry, general Life sciences Biochemistry Amyloid beta- (DE-588)4385528-3 gnd Proteine (DE-588)4076388-2 gnd Labortechnik (DE-588)4123602-6 gnd |
| subject_GND | (DE-588)4385528-3 (DE-588)4076388-2 (DE-588)4123602-6 (DE-588)4143413-4 |
| title | Amyloid Proteins Methods and Protocols |
| title_auth | Amyloid Proteins Methods and Protocols |
| title_exact_search | Amyloid Proteins Methods and Protocols |
| title_full | Amyloid Proteins Methods and Protocols edited by Einar M. Sigurdsson |
| title_fullStr | Amyloid Proteins Methods and Protocols edited by Einar M. Sigurdsson |
| title_full_unstemmed | Amyloid Proteins Methods and Protocols edited by Einar M. Sigurdsson |
| title_short | Amyloid Proteins |
| title_sort | amyloid proteins methods and protocols |
| title_sub | Methods and Protocols |
| topic | Life Sciences Biochemistry, general Life sciences Biochemistry Amyloid beta- (DE-588)4385528-3 gnd Proteine (DE-588)4076388-2 gnd Labortechnik (DE-588)4123602-6 gnd |
| topic_facet | Life Sciences Biochemistry, general Life sciences Biochemistry Amyloid beta- Proteine Labortechnik Aufsatzsammlung |
| url | https://doi.org/10.1385/1592598749 |
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