Wnt Signaling: Pathway Methods and Mammalian Models
Since their discovery, Wnt signaling molecules have been shown to control key events in embryogenesis, to maintain tissue homeostasis in the adult and, when aberrantly activated, to promote human degenerative diseases and cancer, thus making them a vital area of study. Wnt Signaling: Methods and Pro...
Gespeichert in:
| Weitere Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2008
|
| Schriftenreihe: | Methods in Molecular Biology™
468 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | Since their discovery, Wnt signaling molecules have been shown to control key events in embryogenesis, to maintain tissue homeostasis in the adult and, when aberrantly activated, to promote human degenerative diseases and cancer, thus making them a vital area of study. Wnt Signaling: Methods and Protocols examines both biochemical assays and vertebrate and invertebrate model systems to provide a point of reference to current molecular protocols and the diverse model systems employed to study this important signaling pathway. In Volume 1, Pathway Methods and Mammalian Models, assays to measure activation of the diverse Wnt signaling pathways are explored, along with a selection of models and strategies used to study mammalian Wnt/FZD fuction, from protein-protein interaction and simple cell line models to organoid cultures and mouse models. As a volume in the highly successful Methods in Molecular Biology™ series, chapters contain readily reproducible laboratory protocols, complete with lists of necessary equipment and reagents and the Notes section, which reveals helpful troubleshooting tips. Comprehensive and cutting-edge, Wnt Signaling: Methods and Protocols collects the expertise and knowledge of many leaders in the field to produce this invaluable two-volume resource. |
| Beschreibung: | 1 Online-Ressource (XVI, 336 p. 76 illus., 2 illus. in color) |
| ISBN: | 9781597452496 |
| DOI: | 10.1007/978-1-59745-249-6 |
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| spelling | Wnt Signaling Pathway Methods and Mammalian Models edited by Elizabeth Vincan Totowa, NJ Humana Press 2008 1 Online-Ressource (XVI, 336 p. 76 illus., 2 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology™ 468 Since their discovery, Wnt signaling molecules have been shown to control key events in embryogenesis, to maintain tissue homeostasis in the adult and, when aberrantly activated, to promote human degenerative diseases and cancer, thus making them a vital area of study. Wnt Signaling: Methods and Protocols examines both biochemical assays and vertebrate and invertebrate model systems to provide a point of reference to current molecular protocols and the diverse model systems employed to study this important signaling pathway. In Volume 1, Pathway Methods and Mammalian Models, assays to measure activation of the diverse Wnt signaling pathways are explored, along with a selection of models and strategies used to study mammalian Wnt/FZD fuction, from protein-protein interaction and simple cell line models to organoid cultures and mouse models. As a volume in the highly successful Methods in Molecular Biology™ series, chapters contain readily reproducible laboratory protocols, complete with lists of necessary equipment and reagents and the Notes section, which reveals helpful troubleshooting tips. Comprehensive and cutting-edge, Wnt Signaling: Methods and Protocols collects the expertise and knowledge of many leaders in the field to produce this invaluable two-volume resource. Life Sciences Cell Biology Life sciences Cell biology Vincan, Elizabeth edt Erscheint auch als Druck-Ausgabe 9781588299123 https://doi.org/10.1007/978-1-59745-249-6 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Wnt Signaling Pathway Methods and Mammalian Models Life Sciences Cell Biology Life sciences Cell biology |
| title | Wnt Signaling Pathway Methods and Mammalian Models |
| title_auth | Wnt Signaling Pathway Methods and Mammalian Models |
| title_exact_search | Wnt Signaling Pathway Methods and Mammalian Models |
| title_full | Wnt Signaling Pathway Methods and Mammalian Models edited by Elizabeth Vincan |
| title_fullStr | Wnt Signaling Pathway Methods and Mammalian Models edited by Elizabeth Vincan |
| title_full_unstemmed | Wnt Signaling Pathway Methods and Mammalian Models edited by Elizabeth Vincan |
| title_short | Wnt Signaling |
| title_sort | wnt signaling pathway methods and mammalian models |
| title_sub | Pathway Methods and Mammalian Models |
| topic | Life Sciences Cell Biology Life sciences Cell biology |
| topic_facet | Life Sciences Cell Biology Life sciences Cell biology |
| url | https://doi.org/10.1007/978-1-59745-249-6 |
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