Ubiquitin-Proteasome Protocols:
The targeted addition of ubiquitin to proteins is now known to regulate many cellular events, with the enzymes involved in protein ubiquitination linked to a variety of clinical problems, such as cancer, heart disease, and immune dysfunction. In Ubiquitin-Proteasome Protocols, hands-on leaders in th...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2005
|
| Schriftenreihe: | Methods in Molecular Biology™
301 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | The targeted addition of ubiquitin to proteins is now known to regulate many cellular events, with the enzymes involved in protein ubiquitination linked to a variety of clinical problems, such as cancer, heart disease, and immune dysfunction. In Ubiquitin-Proteasome Protocols, hands-on leaders in the field, many of whom originally developed the methods they describe, detail cutting-edge techniques for studying ubiquitin-dependent protein degradation via the proteasome. The topics covered range broadly from basic biochemistry to cellular assays to discovery techniques using mass spectrometric analysis. These biochemical and cellular methods are necessary to explore the ubiquitin-proteasome system and ubiquitin-proteasome- dependent functions. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. State-of-the-art and user-friendly, Ubiquitin-Proteasome Protocols offers novice and experienced bench scientists alike a thorough compendium of readily reproducible techniques that will accelerate discovery, enhance productivity, and permit manipulation of the system for varied research purposes |
| Beschreibung: | 1 Online-Ressource (XII, 381 p. 172 illus) |
| ISBN: | 9781592598953 |
| DOI: | 10.1385/1592598951 |
Internformat
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Datensatz im Suchindex
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| spelling | Ubiquitin-Proteasome Protocols edited by Cam Patterson, Douglas M. Cyr Totowa, NJ Humana Press 2005 1 Online-Ressource (XII, 381 p. 172 illus) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology™ 301 The targeted addition of ubiquitin to proteins is now known to regulate many cellular events, with the enzymes involved in protein ubiquitination linked to a variety of clinical problems, such as cancer, heart disease, and immune dysfunction. In Ubiquitin-Proteasome Protocols, hands-on leaders in the field, many of whom originally developed the methods they describe, detail cutting-edge techniques for studying ubiquitin-dependent protein degradation via the proteasome. The topics covered range broadly from basic biochemistry to cellular assays to discovery techniques using mass spectrometric analysis. These biochemical and cellular methods are necessary to explore the ubiquitin-proteasome system and ubiquitin-proteasome- dependent functions. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. State-of-the-art and user-friendly, Ubiquitin-Proteasome Protocols offers novice and experienced bench scientists alike a thorough compendium of readily reproducible techniques that will accelerate discovery, enhance productivity, and permit manipulation of the system for varied research purposes Life Sciences Biochemistry, general Life sciences Biochemistry Biologisches Verfahren (DE-588)4361950-2 gnd rswk-swf Ubiquitin (DE-588)4314848-7 gnd rswk-swf Proteasom (DE-588)4315827-4 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Ubiquitin (DE-588)4314848-7 s Proteasom (DE-588)4315827-4 s Biologisches Verfahren (DE-588)4361950-2 s b DE-604 Patterson, Cam edt Cyr, Douglas M. edt Erscheint auch als Druck-Ausgabe 9781588292520 https://doi.org/10.1385/1592598951 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Ubiquitin-Proteasome Protocols Life Sciences Biochemistry, general Life sciences Biochemistry Biologisches Verfahren (DE-588)4361950-2 gnd Ubiquitin (DE-588)4314848-7 gnd Proteasom (DE-588)4315827-4 gnd |
| subject_GND | (DE-588)4361950-2 (DE-588)4314848-7 (DE-588)4315827-4 (DE-588)4143413-4 |
| title | Ubiquitin-Proteasome Protocols |
| title_auth | Ubiquitin-Proteasome Protocols |
| title_exact_search | Ubiquitin-Proteasome Protocols |
| title_full | Ubiquitin-Proteasome Protocols edited by Cam Patterson, Douglas M. Cyr |
| title_fullStr | Ubiquitin-Proteasome Protocols edited by Cam Patterson, Douglas M. Cyr |
| title_full_unstemmed | Ubiquitin-Proteasome Protocols edited by Cam Patterson, Douglas M. Cyr |
| title_short | Ubiquitin-Proteasome Protocols |
| title_sort | ubiquitin proteasome protocols |
| topic | Life Sciences Biochemistry, general Life sciences Biochemistry Biologisches Verfahren (DE-588)4361950-2 gnd Ubiquitin (DE-588)4314848-7 gnd Proteasom (DE-588)4315827-4 gnd |
| topic_facet | Life Sciences Biochemistry, general Life sciences Biochemistry Biologisches Verfahren Ubiquitin Proteasom Aufsatzsammlung |
| url | https://doi.org/10.1385/1592598951 |
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