C. elegans: Methods and Applications
Molecular biology has driven a powerful reductionist, or "molecule-c- tric," approach to biological research in the last half of the 20th century. Red- tionism is the attempt to explain complex phenomena by defining the functional properties of the individual components of the system. Bloo...
Gespeichert in:
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2006
|
| Schriftenreihe: | Methods in Molecular Biology
351 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 URL des Erstveröffentlichers |
| Zusammenfassung: | Molecular biology has driven a powerful reductionist, or "molecule-c- tric," approach to biological research in the last half of the 20th century. Red- tionism is the attempt to explain complex phenomena by defining the functional properties of the individual components of the system. Bloom (1) has referred to the post-genome sequencing era as the end of "naïve reductionism. " Red- tionist methods will continue to be an essential element of all biological research efforts, but "naïve reductionism," the belief that reductionism alone can lead to a complete understanding of living organisms, is not tenable. Organisms are clearly much more than the sum of their parts, and the behavior of complex physiological processes cannot be understood simply by knowing how the parts work in isolation. Systems biology has emerged in the wake of genome sequencing as the s- cessor to reductionism (2–5). The "systems" of systems biology are defined over a wide span of complexity ranging from two macromolecules that interact to carry out a specific task to whole organisms. Systems biology is integrative and seeks to understand and predict the behavior or "emergent" properties of complex, multicomponent biological processes. A systems-level characteri- tion of a biological process addresses the following three main questions: (1) What are the parts of the system (i. e |
| Beschreibung: | 1 Online-Ressource (XII, 292 p. 42 illus) |
| ISBN: | 9781597451512 |
| DOI: | 10.1385/1597451517 |
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| 520 | |a Molecular biology has driven a powerful reductionist, or "molecule-c- tric," approach to biological research in the last half of the 20th century. Red- tionism is the attempt to explain complex phenomena by defining the functional properties of the individual components of the system. Bloom (1) has referred to the post-genome sequencing era as the end of "naïve reductionism. " Red- tionist methods will continue to be an essential element of all biological research efforts, but "naïve reductionism," the belief that reductionism alone can lead to a complete understanding of living organisms, is not tenable. Organisms are clearly much more than the sum of their parts, and the behavior of complex physiological processes cannot be understood simply by knowing how the parts work in isolation. Systems biology has emerged in the wake of genome sequencing as the s- cessor to reductionism (2–5). The "systems" of systems biology are defined over a wide span of complexity ranging from two macromolecules that interact to carry out a specific task to whole organisms. Systems biology is integrative and seeks to understand and predict the behavior or "emergent" properties of complex, multicomponent biological processes. A systems-level characteri- tion of a biological process addresses the following three main questions: (1) What are the parts of the system (i. e | ||
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Datensatz im Suchindex
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| any_adam_object | |
| author2 | Strange, Kevin |
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| indexdate | 2024-07-10T08:05:34Z |
| institution | BVB |
| isbn | 9781597451512 |
| language | English |
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| spelling | C. elegans Methods and Applications edited by Kevin Strange Totowa, NJ Humana Press 2006 1 Online-Ressource (XII, 292 p. 42 illus) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 351 Molecular biology has driven a powerful reductionist, or "molecule-c- tric," approach to biological research in the last half of the 20th century. Red- tionism is the attempt to explain complex phenomena by defining the functional properties of the individual components of the system. Bloom (1) has referred to the post-genome sequencing era as the end of "naïve reductionism. " Red- tionist methods will continue to be an essential element of all biological research efforts, but "naïve reductionism," the belief that reductionism alone can lead to a complete understanding of living organisms, is not tenable. Organisms are clearly much more than the sum of their parts, and the behavior of complex physiological processes cannot be understood simply by knowing how the parts work in isolation. Systems biology has emerged in the wake of genome sequencing as the s- cessor to reductionism (2–5). The "systems" of systems biology are defined over a wide span of complexity ranging from two macromolecules that interact to carry out a specific task to whole organisms. Systems biology is integrative and seeks to understand and predict the behavior or "emergent" properties of complex, multicomponent biological processes. A systems-level characteri- tion of a biological process addresses the following three main questions: (1) What are the parts of the system (i. e Biomedicine Human Genetics Medicine Human genetics Molekulargenetik (DE-588)4039987-4 gnd rswk-swf Physiologie (DE-588)4045981-0 gnd rswk-swf Caenorhabditis elegans (DE-588)4147127-1 gnd rswk-swf Labortechnik (DE-588)4123602-6 gnd rswk-swf Caenorhabditis elegans (DE-588)4147127-1 s Physiologie (DE-588)4045981-0 s Labortechnik (DE-588)4123602-6 s DE-604 Molekulargenetik (DE-588)4039987-4 s b DE-604 Strange, Kevin edt Erscheint auch als Druck-Ausgabe 9781588295972 https://doi.org/10.1385/1597451517 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | C. elegans Methods and Applications Biomedicine Human Genetics Medicine Human genetics Molekulargenetik (DE-588)4039987-4 gnd Physiologie (DE-588)4045981-0 gnd Caenorhabditis elegans (DE-588)4147127-1 gnd Labortechnik (DE-588)4123602-6 gnd |
| subject_GND | (DE-588)4039987-4 (DE-588)4045981-0 (DE-588)4147127-1 (DE-588)4123602-6 |
| title | C. elegans Methods and Applications |
| title_auth | C. elegans Methods and Applications |
| title_exact_search | C. elegans Methods and Applications |
| title_full | C. elegans Methods and Applications edited by Kevin Strange |
| title_fullStr | C. elegans Methods and Applications edited by Kevin Strange |
| title_full_unstemmed | C. elegans Methods and Applications edited by Kevin Strange |
| title_short | C. elegans |
| title_sort | c elegans methods and applications |
| title_sub | Methods and Applications |
| topic | Biomedicine Human Genetics Medicine Human genetics Molekulargenetik (DE-588)4039987-4 gnd Physiologie (DE-588)4045981-0 gnd Caenorhabditis elegans (DE-588)4147127-1 gnd Labortechnik (DE-588)4123602-6 gnd |
| topic_facet | Biomedicine Human Genetics Medicine Human genetics Molekulargenetik Physiologie Caenorhabditis elegans Labortechnik |
| url | https://doi.org/10.1385/1597451517 |
| work_keys_str_mv | AT strangekevin celegansmethodsandapplications |