Single Nucleotide Polymorphisms: Methods and Protocols
In recent years, single nucleotide polymorphisms have received increased and special attention in a rapidly developing field of personalized medicine and drug treatment. Comprising more than eighty percent of all known polymorphisms, single nucleotide polymorphisms (SNPs) are primarily responsible f...
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2009
|
| Ausgabe: | 2 |
| Schriftenreihe: | Methods in Molecular Biology™, Methods and Protocols
578 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | In recent years, single nucleotide polymorphisms have received increased and special attention in a rapidly developing field of personalized medicine and drug treatment. Comprising more than eighty percent of all known polymorphisms, single nucleotide polymorphisms (SNPs) are primarily responsible for phenotypic differences between individuals, and have been suggested to affect the development of diseases in humans and the response to drug treatment and environmental stress. In Single Nucleotide Polymorphisms: Methods and Protocols, Second Edition, expert researchers explore the latest advances in this area, highlighting the substantial progress that has been made in SNP genotyping, examining recent developments in high-throughput genotyping approaches, and exploring our new understanding of the impact of SNPs on gene function. Chapters address the impact of SNPs on phenotype, examine SNP databases, look at methods that have been applied for SNP bioinformatics discovery and analysis, and discuss advanced experimental approaches used for SNP detection. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Current and innovative, Single Nucleotide Polymorphisms: Methods and Protocols, Second Edition is an essential guidebook for individual researchers as well as institutions and companies working in the field |
| Beschreibung: | 1 Online-Ressource (XIV, 464 p. 100 illus., 18 illus. in color) |
| ISBN: | 9781603274111 |
| DOI: | 10.1007/978-1-60327-411-1 |
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| 520 | |a In recent years, single nucleotide polymorphisms have received increased and special attention in a rapidly developing field of personalized medicine and drug treatment. Comprising more than eighty percent of all known polymorphisms, single nucleotide polymorphisms (SNPs) are primarily responsible for phenotypic differences between individuals, and have been suggested to affect the development of diseases in humans and the response to drug treatment and environmental stress. In Single Nucleotide Polymorphisms: Methods and Protocols, Second Edition, expert researchers explore the latest advances in this area, highlighting the substantial progress that has been made in SNP genotyping, examining recent developments in high-throughput genotyping approaches, and exploring our new understanding of the impact of SNPs on gene function. Chapters address the impact of SNPs on phenotype, examine SNP databases, look at methods that have been applied for SNP bioinformatics discovery and analysis, and discuss advanced experimental approaches used for SNP detection. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Current and innovative, Single Nucleotide Polymorphisms: Methods and Protocols, Second Edition is an essential guidebook for individual researchers as well as institutions and companies working in the field | ||
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| spelling | Single Nucleotide Polymorphisms Methods and Protocols edited by Anton A. Komar 2 Totowa, NJ Humana Press 2009 1 Online-Ressource (XIV, 464 p. 100 illus., 18 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology™, Methods and Protocols 578 In recent years, single nucleotide polymorphisms have received increased and special attention in a rapidly developing field of personalized medicine and drug treatment. Comprising more than eighty percent of all known polymorphisms, single nucleotide polymorphisms (SNPs) are primarily responsible for phenotypic differences between individuals, and have been suggested to affect the development of diseases in humans and the response to drug treatment and environmental stress. In Single Nucleotide Polymorphisms: Methods and Protocols, Second Edition, expert researchers explore the latest advances in this area, highlighting the substantial progress that has been made in SNP genotyping, examining recent developments in high-throughput genotyping approaches, and exploring our new understanding of the impact of SNPs on gene function. Chapters address the impact of SNPs on phenotype, examine SNP databases, look at methods that have been applied for SNP bioinformatics discovery and analysis, and discuss advanced experimental approaches used for SNP detection. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Current and innovative, Single Nucleotide Polymorphisms: Methods and Protocols, Second Edition is an essential guidebook for individual researchers as well as institutions and companies working in the field Biomedicine Human Genetics Cell Biology Gene Function Medicine Human genetics Medical genetics Cell biology Komar, Anton A. edt Erscheint auch als Druck-Ausgabe 9781603274104 https://doi.org/10.1007/978-1-60327-411-1 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Single Nucleotide Polymorphisms Methods and Protocols Biomedicine Human Genetics Cell Biology Gene Function Medicine Human genetics Medical genetics Cell biology |
| title | Single Nucleotide Polymorphisms Methods and Protocols |
| title_auth | Single Nucleotide Polymorphisms Methods and Protocols |
| title_exact_search | Single Nucleotide Polymorphisms Methods and Protocols |
| title_full | Single Nucleotide Polymorphisms Methods and Protocols edited by Anton A. Komar |
| title_fullStr | Single Nucleotide Polymorphisms Methods and Protocols edited by Anton A. Komar |
| title_full_unstemmed | Single Nucleotide Polymorphisms Methods and Protocols edited by Anton A. Komar |
| title_short | Single Nucleotide Polymorphisms |
| title_sort | single nucleotide polymorphisms methods and protocols |
| title_sub | Methods and Protocols |
| topic | Biomedicine Human Genetics Cell Biology Gene Function Medicine Human genetics Medical genetics Cell biology |
| topic_facet | Biomedicine Human Genetics Cell Biology Gene Function Medicine Human genetics Medical genetics Cell biology |
| url | https://doi.org/10.1007/978-1-60327-411-1 |
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