Riboswitches: Methods and Protocols
The revolutionary discoveries of RNA interference and bacterial regulatory RNAs led to further breakthroughs such as the identification of riboswitches and related RNA sensors, mRNA regions capable of alternating their conformations in response to the presence of cellular metabolites and other physi...
Gespeichert in:
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2009
|
| Schriftenreihe: | Methods in Molecular Biology, Methods and Protocols
540 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | The revolutionary discoveries of RNA interference and bacterial regulatory RNAs led to further breakthroughs such as the identification of riboswitches and related RNA sensors, mRNA regions capable of alternating their conformations in response to the presence of cellular metabolites and other physical or chemical cues. In Riboswitches: Methods and Protocols, expert researchers provide comprehensive and up-to-date coverage of various methods used to study riboswitches and other RNAs involved in gene expression control. Examining biochemical and modern biophysical techniques, the volume focuses on mRNAs responding to small organic molecules but expands the definition of a riboswitch to incorporate classes of RNA that undergo conformational transitions in response to other stimuli in order to control the expression of genes. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Riboswitches: Methods and Protocols promises to inspire both novices and experts working in a wide range of contemporary biological areas who wish to further develop their RNA methodology |
| Beschreibung: | 1 Online-Ressource (XI, 366 p. 65 illus) |
| ISBN: | 9781597455589 |
| DOI: | 10.1007/978-1-59745-558-9 |
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| isbn | 9781597455589 |
| language | English |
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| spelling | Riboswitches Methods and Protocols edited by Alexander Serganov Totowa, NJ Humana Press 2009 1 Online-Ressource (XI, 366 p. 65 illus) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology, Methods and Protocols 540 The revolutionary discoveries of RNA interference and bacterial regulatory RNAs led to further breakthroughs such as the identification of riboswitches and related RNA sensors, mRNA regions capable of alternating their conformations in response to the presence of cellular metabolites and other physical or chemical cues. In Riboswitches: Methods and Protocols, expert researchers provide comprehensive and up-to-date coverage of various methods used to study riboswitches and other RNAs involved in gene expression control. Examining biochemical and modern biophysical techniques, the volume focuses on mRNAs responding to small organic molecules but expands the definition of a riboswitch to incorporate classes of RNA that undergo conformational transitions in response to other stimuli in order to control the expression of genes. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Riboswitches: Methods and Protocols promises to inspire both novices and experts working in a wide range of contemporary biological areas who wish to further develop their RNA methodology Life Sciences Biochemistry, general Nucleic Acid Chemistry Gene Expression Life sciences Gene expression Biochemistry Nucleic acids Serganov, Alexander edt Erscheint auch als Druck-Ausgabe 9781934115886 https://doi.org/10.1007/978-1-59745-558-9 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Riboswitches Methods and Protocols Life Sciences Biochemistry, general Nucleic Acid Chemistry Gene Expression Life sciences Gene expression Biochemistry Nucleic acids |
| title | Riboswitches Methods and Protocols |
| title_auth | Riboswitches Methods and Protocols |
| title_exact_search | Riboswitches Methods and Protocols |
| title_full | Riboswitches Methods and Protocols edited by Alexander Serganov |
| title_fullStr | Riboswitches Methods and Protocols edited by Alexander Serganov |
| title_full_unstemmed | Riboswitches Methods and Protocols edited by Alexander Serganov |
| title_short | Riboswitches |
| title_sort | riboswitches methods and protocols |
| title_sub | Methods and Protocols |
| topic | Life Sciences Biochemistry, general Nucleic Acid Chemistry Gene Expression Life sciences Gene expression Biochemistry Nucleic acids |
| topic_facet | Life Sciences Biochemistry, general Nucleic Acid Chemistry Gene Expression Life sciences Gene expression Biochemistry Nucleic acids |
| url | https://doi.org/10.1007/978-1-59745-558-9 |
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