Metallo-drugs: development and action of anticancer agents
"Volume 18, entitled Metallo-Drugs: Development and Action of Anticancer Agents of the series Metal Ions in Life Sciences centers on biological, medicinal inorganic chemistry. The serendipitous discovery of the antitumor activity of cis-diamminodichloroplatinum(II) (cisplatin) by Barnett Rosenb...
Gespeichert in:
| Weitere Verfasser: | , , , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Berlin
Walter de Gruyter GmbH
[2018]
|
| Schriftenreihe: | Metal ions in life sciences
volume 18 |
| Schlagworte: | |
| Online-Zugang: | FHA01 FHM01 FHR01 FKE01 FLA01 UPA01 FAW01 FAB01 FCO01 URL des Erstveröffentlichers |
| Zusammenfassung: | "Volume 18, entitled Metallo-Drugs: Development and Action of Anticancer Agents of the series Metal Ions in Life Sciences centers on biological, medicinal inorganic chemistry. The serendipitous discovery of the antitumor activity of cis-diamminodichloroplatinum(II) (cisplatin) by Barnett Rosenberg in the 1960s is a landmark in metallodrug-based chemotherapy. The success of cisplatin in the clinic, followed by oxaliplatin and carboplatin, along with their drawbacks relating mainly to resistance development and severe toxicity, initiated research on polynuclear platinum complexes and on Pt(IV) complexes as prodrugs. Furthermore, the indicated shortcomings led to the exploration of other transition and main group metal ions, among them Ru(II/III), Au(I/III), Ti(IV), V(IV/V), and Ga(III) including also the essential metal ions Fe(II/III), Cu(I/II), and Zn(II). Ionic as well as covalent and non-covalent interactions between structurally very different complexes and biomolecules like nucleic acids, proteins, and carbohydrates are studied and discussed with regard to their possible anticancer actions. Hence, MILS-18 summarizes the research at the forefront of medicinal inorganic chemistry, including studies on the next-generation, tailor-made anticancer drugs. All this and more is treated in an authoritative and timely manner in the 17 stimulating chapters of this book, written by 39 internationally recognized experts from 10 nations (from the US via Europe to China and Australia). The impact of this vibrant research area is manifested by more than 2700 references, nearly 150 illustrations (more than half in color) and several comprehensive tables. Metallo-Drugs: Development and Action of Anticancer Agents is an essential resource for scientists working in the wide range from enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that it also provides excellent information for teaching"...Provided by publisher |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | 1 Online-Ressource (xlii, 546 Seiten) |
| ISBN: | 9783110470734 |
| DOI: | 10.1515/9783110470734 |
Internformat
MARC
| LEADER | 00000nmm a2200000 cb4500 | ||
|---|---|---|---|
| 001 | BV044852812 | ||
| 003 | DE-604 | ||
| 005 | 20190418 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 180305s2018 gw |||| o||u| ||||||eng d | ||
| 020 | |a 9783110470734 |c Online |9 978-3-11-047073-4 | ||
| 024 | 7 | |a 10.1515/9783110470734 |2 doi | |
| 035 | |a (OCoLC)1048450375 | ||
| 035 | |a (DE-599)BVBBV044852812 | ||
| 040 | |a DE-604 |b ger |e rda | ||
| 041 | 0 | |a eng | |
| 044 | |a gw |c DE | ||
| 049 | |a DE-860 |a DE-859 |a DE-Aug4 |a DE-739 |a DE-898 |a DE-M347 |a DE-1046 |a DE-1043 |a DE-858 | ||
| 050 | 0 | |a RS431.A64 | |
| 082 | 0 | |a 615.7/98 |2 23 | |
| 084 | |a VH 9750 |0 (DE-625)147385:253 |2 rvk | ||
| 245 | 1 | 0 | |a Metallo-drugs |b development and action of anticancer agents |c edited by Astrid Sigel, Helmut Sigel, Eva Freisinger, and Roland K.O. Sigel |
| 264 | 1 | |a Berlin |b Walter de Gruyter GmbH |c [2018] | |
| 264 | 4 | |c © 2018 | |
| 300 | |a 1 Online-Ressource (xlii, 546 Seiten) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 490 | 0 | |a Metal ions in life sciences |v volume 18 | |
| 500 | |a Includes bibliographical references and index | ||
| 520 | |a "Volume 18, entitled Metallo-Drugs: Development and Action of Anticancer Agents of the series Metal Ions in Life Sciences centers on biological, medicinal inorganic chemistry. The serendipitous discovery of the antitumor activity of cis-diamminodichloroplatinum(II) (cisplatin) by Barnett Rosenberg in the 1960s is a landmark in metallodrug-based chemotherapy. The success of cisplatin in the clinic, followed by oxaliplatin and carboplatin, along with their drawbacks relating mainly to resistance development and severe toxicity, initiated research on polynuclear platinum complexes and on Pt(IV) complexes as prodrugs. Furthermore, the indicated shortcomings led to the exploration of other transition and main group metal ions, among them Ru(II/III), Au(I/III), Ti(IV), V(IV/V), and Ga(III) including also the essential metal ions Fe(II/III), Cu(I/II), and Zn(II). | ||
| 520 | |a Ionic as well as covalent and non-covalent interactions between structurally very different complexes and biomolecules like nucleic acids, proteins, and carbohydrates are studied and discussed with regard to their possible anticancer actions. Hence, MILS-18 summarizes the research at the forefront of medicinal inorganic chemistry, including studies on the next-generation, tailor-made anticancer drugs. All this and more is treated in an authoritative and timely manner in the 17 stimulating chapters of this book, written by 39 internationally recognized experts from 10 nations (from the US via Europe to China and Australia). The impact of this vibrant research area is manifested by more than 2700 references, nearly 150 illustrations (more than half in color) and several comprehensive tables. | ||
| 520 | |a Metallo-Drugs: Development and Action of Anticancer Agents is an essential resource for scientists working in the wide range from enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that it also provides excellent information for teaching"...Provided by publisher | ||
| 650 | 4 | |a Organoplatinum Compounds | |
| 650 | 4 | |a Antineoplastic Agents | |
| 650 | 4 | |a Cisplatin | |
| 700 | 1 | |a Sigel, Astrid |0 (DE-588)103367866X |4 edt | |
| 700 | 1 | |a Sigel, Helmut |0 (DE-588)1131173953 |4 edt | |
| 700 | 1 | |a Freisinger, Eva |d 1972- |0 (DE-588)122154193 |4 edt | |
| 700 | 1 | |a Sigel, Roland K. O. |d 1971- |0 (DE-588)121647366 |4 edt | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 978-3-11-046984-4 |
| 856 | 4 | 0 | |u https://doi.org/10.1515/9783110470734 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
| 912 | |a ZDB-23-DPC |a ZDB-23-DGG | ||
| 940 | 1 | |q ZDB-23-DPC18 | |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-030247668 | ||
| 966 | e | |u https://doi.org/10.1515/9783110470734 |l FHA01 |p ZDB-23-DGG |q FHA_PDA_DGG |x Verlag |3 Volltext | |
| 966 | e | |u https://doi.org/10.1515/9783110470734 |l FHM01 |p ZDB-23-DPC |q ZDB-23-DPC18 |x Verlag |3 Volltext | |
| 966 | e | |u https://doi.org/10.1515/9783110470734 |l FHR01 |p ZDB-23-DPC |q ZDB-23-DPC18 |x Verlag |3 Volltext | |
| 966 | e | |u https://doi.org/10.1515/9783110470734 |l FKE01 |p ZDB-23-DGG |q FKE_PDA_DGG |x Verlag |3 Volltext | |
| 966 | e | |u https://doi.org/10.1515/9783110470734 |l FLA01 |p ZDB-23-DGG |q FLA_PDA_DGG |x Verlag |3 Volltext | |
| 966 | e | |u https://doi.org/10.1515/9783110470734 |l UPA01 |p ZDB-23-DGG |q UPA_PDA_DGG |x Verlag |3 Volltext | |
| 966 | e | |u https://doi.org/10.1515/9783110470734 |l FAW01 |p ZDB-23-DGG |q FAW_PDA_DGG |x Verlag |3 Volltext | |
| 966 | e | |u https://doi.org/10.1515/9783110470734 |l FAB01 |p ZDB-23-DGG |q FAB_PDA_DGG |x Verlag |3 Volltext | |
| 966 | e | |u https://doi.org/10.1515/9783110470734 |l FCO01 |p ZDB-23-DGG |q FCO_PDA_DGG |x Verlag |3 Volltext | |
Datensatz im Suchindex
| _version_ | 1804178370380955648 |
|---|---|
| any_adam_object | |
| author2 | Sigel, Astrid Sigel, Helmut Freisinger, Eva 1972- Sigel, Roland K. O. 1971- |
| author2_role | edt edt edt edt |
| author2_variant | a s as h s hs e f ef r k o s rko rkos |
| author_GND | (DE-588)103367866X (DE-588)1131173953 (DE-588)122154193 (DE-588)121647366 |
| author_facet | Sigel, Astrid Sigel, Helmut Freisinger, Eva 1972- Sigel, Roland K. O. 1971- |
| building | Verbundindex |
| bvnumber | BV044852812 |
| callnumber-first | R - Medicine |
| callnumber-label | RS431 |
| callnumber-raw | RS431.A64 |
| callnumber-search | RS431.A64 |
| callnumber-sort | RS 3431 A64 |
| callnumber-subject | RS - Pharmacy |
| classification_rvk | VH 9750 |
| collection | ZDB-23-DPC ZDB-23-DGG |
| ctrlnum | (OCoLC)1048450375 (DE-599)BVBBV044852812 |
| dewey-full | 615.7/98 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615.7/98 |
| dewey-search | 615.7/98 |
| dewey-sort | 3615.7 298 |
| dewey-tens | 610 - Medicine and health |
| discipline | Chemie / Pharmazie Medizin |
| doi_str_mv | 10.1515/9783110470734 |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>04775nmm a2200613 cb4500</leader><controlfield tag="001">BV044852812</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20190418 </controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">180305s2018 gw |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9783110470734</subfield><subfield code="c">Online</subfield><subfield code="9">978-3-11-047073-4</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1515/9783110470734</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1048450375</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV044852812</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="044" ind1=" " ind2=" "><subfield code="a">gw</subfield><subfield code="c">DE</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-860</subfield><subfield code="a">DE-859</subfield><subfield code="a">DE-Aug4</subfield><subfield code="a">DE-739</subfield><subfield code="a">DE-898</subfield><subfield code="a">DE-M347</subfield><subfield code="a">DE-1046</subfield><subfield code="a">DE-1043</subfield><subfield code="a">DE-858</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RS431.A64</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">615.7/98</subfield><subfield code="2">23</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">VH 9750</subfield><subfield code="0">(DE-625)147385:253</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Metallo-drugs</subfield><subfield code="b">development and action of anticancer agents</subfield><subfield code="c">edited by Astrid Sigel, Helmut Sigel, Eva Freisinger, and Roland K.O. Sigel</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Berlin</subfield><subfield code="b">Walter de Gruyter GmbH</subfield><subfield code="c">[2018]</subfield></datafield><datafield tag="264" ind1=" " ind2="4"><subfield code="c">© 2018</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (xlii, 546 Seiten)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Metal ions in life sciences</subfield><subfield code="v">volume 18</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Includes bibliographical references and index</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">"Volume 18, entitled Metallo-Drugs: Development and Action of Anticancer Agents of the series Metal Ions in Life Sciences centers on biological, medicinal inorganic chemistry. The serendipitous discovery of the antitumor activity of cis-diamminodichloroplatinum(II) (cisplatin) by Barnett Rosenberg in the 1960s is a landmark in metallodrug-based chemotherapy. The success of cisplatin in the clinic, followed by oxaliplatin and carboplatin, along with their drawbacks relating mainly to resistance development and severe toxicity, initiated research on polynuclear platinum complexes and on Pt(IV) complexes as prodrugs. Furthermore, the indicated shortcomings led to the exploration of other transition and main group metal ions, among them Ru(II/III), Au(I/III), Ti(IV), V(IV/V), and Ga(III) including also the essential metal ions Fe(II/III), Cu(I/II), and Zn(II). </subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Ionic as well as covalent and non-covalent interactions between structurally very different complexes and biomolecules like nucleic acids, proteins, and carbohydrates are studied and discussed with regard to their possible anticancer actions. Hence, MILS-18 summarizes the research at the forefront of medicinal inorganic chemistry, including studies on the next-generation, tailor-made anticancer drugs. All this and more is treated in an authoritative and timely manner in the 17 stimulating chapters of this book, written by 39 internationally recognized experts from 10 nations (from the US via Europe to China and Australia). The impact of this vibrant research area is manifested by more than 2700 references, nearly 150 illustrations (more than half in color) and several comprehensive tables. </subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Metallo-Drugs: Development and Action of Anticancer Agents is an essential resource for scientists working in the wide range from enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that it also provides excellent information for teaching"...Provided by publisher</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Organoplatinum Compounds</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Antineoplastic Agents</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cisplatin</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sigel, Astrid</subfield><subfield code="0">(DE-588)103367866X</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sigel, Helmut</subfield><subfield code="0">(DE-588)1131173953</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Freisinger, Eva</subfield><subfield code="d">1972-</subfield><subfield code="0">(DE-588)122154193</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sigel, Roland K. O.</subfield><subfield code="d">1971-</subfield><subfield code="0">(DE-588)121647366</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">978-3-11-046984-4</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1515/9783110470734</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-23-DPC</subfield><subfield code="a">ZDB-23-DGG</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">ZDB-23-DPC18</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-030247668</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1515/9783110470734</subfield><subfield code="l">FHA01</subfield><subfield code="p">ZDB-23-DGG</subfield><subfield code="q">FHA_PDA_DGG</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1515/9783110470734</subfield><subfield code="l">FHM01</subfield><subfield code="p">ZDB-23-DPC</subfield><subfield code="q">ZDB-23-DPC18</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1515/9783110470734</subfield><subfield code="l">FHR01</subfield><subfield code="p">ZDB-23-DPC</subfield><subfield code="q">ZDB-23-DPC18</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1515/9783110470734</subfield><subfield code="l">FKE01</subfield><subfield code="p">ZDB-23-DGG</subfield><subfield code="q">FKE_PDA_DGG</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1515/9783110470734</subfield><subfield code="l">FLA01</subfield><subfield code="p">ZDB-23-DGG</subfield><subfield code="q">FLA_PDA_DGG</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1515/9783110470734</subfield><subfield code="l">UPA01</subfield><subfield code="p">ZDB-23-DGG</subfield><subfield code="q">UPA_PDA_DGG</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1515/9783110470734</subfield><subfield code="l">FAW01</subfield><subfield code="p">ZDB-23-DGG</subfield><subfield code="q">FAW_PDA_DGG</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1515/9783110470734</subfield><subfield code="l">FAB01</subfield><subfield code="p">ZDB-23-DGG</subfield><subfield code="q">FAB_PDA_DGG</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1515/9783110470734</subfield><subfield code="l">FCO01</subfield><subfield code="p">ZDB-23-DGG</subfield><subfield code="q">FCO_PDA_DGG</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| id | DE-604.BV044852812 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:02:54Z |
| institution | BVB |
| isbn | 9783110470734 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-030247668 |
| oclc_num | 1048450375 |
| open_access_boolean | |
| owner | DE-860 DE-859 DE-Aug4 DE-739 DE-898 DE-BY-UBR DE-M347 DE-1046 DE-1043 DE-858 |
| owner_facet | DE-860 DE-859 DE-Aug4 DE-739 DE-898 DE-BY-UBR DE-M347 DE-1046 DE-1043 DE-858 |
| physical | 1 Online-Ressource (xlii, 546 Seiten) |
| psigel | ZDB-23-DPC ZDB-23-DGG ZDB-23-DPC18 ZDB-23-DGG FHA_PDA_DGG ZDB-23-DPC ZDB-23-DPC18 ZDB-23-DGG FKE_PDA_DGG ZDB-23-DGG FLA_PDA_DGG ZDB-23-DGG UPA_PDA_DGG ZDB-23-DGG FAW_PDA_DGG ZDB-23-DGG FAB_PDA_DGG ZDB-23-DGG FCO_PDA_DGG |
| publishDate | 2018 |
| publishDateSearch | 2018 |
| publishDateSort | 2018 |
| publisher | Walter de Gruyter GmbH |
| record_format | marc |
| series2 | Metal ions in life sciences |
| spelling | Metallo-drugs development and action of anticancer agents edited by Astrid Sigel, Helmut Sigel, Eva Freisinger, and Roland K.O. Sigel Berlin Walter de Gruyter GmbH [2018] © 2018 1 Online-Ressource (xlii, 546 Seiten) txt rdacontent c rdamedia cr rdacarrier Metal ions in life sciences volume 18 Includes bibliographical references and index "Volume 18, entitled Metallo-Drugs: Development and Action of Anticancer Agents of the series Metal Ions in Life Sciences centers on biological, medicinal inorganic chemistry. The serendipitous discovery of the antitumor activity of cis-diamminodichloroplatinum(II) (cisplatin) by Barnett Rosenberg in the 1960s is a landmark in metallodrug-based chemotherapy. The success of cisplatin in the clinic, followed by oxaliplatin and carboplatin, along with their drawbacks relating mainly to resistance development and severe toxicity, initiated research on polynuclear platinum complexes and on Pt(IV) complexes as prodrugs. Furthermore, the indicated shortcomings led to the exploration of other transition and main group metal ions, among them Ru(II/III), Au(I/III), Ti(IV), V(IV/V), and Ga(III) including also the essential metal ions Fe(II/III), Cu(I/II), and Zn(II). Ionic as well as covalent and non-covalent interactions between structurally very different complexes and biomolecules like nucleic acids, proteins, and carbohydrates are studied and discussed with regard to their possible anticancer actions. Hence, MILS-18 summarizes the research at the forefront of medicinal inorganic chemistry, including studies on the next-generation, tailor-made anticancer drugs. All this and more is treated in an authoritative and timely manner in the 17 stimulating chapters of this book, written by 39 internationally recognized experts from 10 nations (from the US via Europe to China and Australia). The impact of this vibrant research area is manifested by more than 2700 references, nearly 150 illustrations (more than half in color) and several comprehensive tables. Metallo-Drugs: Development and Action of Anticancer Agents is an essential resource for scientists working in the wide range from enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that it also provides excellent information for teaching"...Provided by publisher Organoplatinum Compounds Antineoplastic Agents Cisplatin Sigel, Astrid (DE-588)103367866X edt Sigel, Helmut (DE-588)1131173953 edt Freisinger, Eva 1972- (DE-588)122154193 edt Sigel, Roland K. O. 1971- (DE-588)121647366 edt Erscheint auch als Druck-Ausgabe 978-3-11-046984-4 https://doi.org/10.1515/9783110470734 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Metallo-drugs development and action of anticancer agents Organoplatinum Compounds Antineoplastic Agents Cisplatin |
| title | Metallo-drugs development and action of anticancer agents |
| title_auth | Metallo-drugs development and action of anticancer agents |
| title_exact_search | Metallo-drugs development and action of anticancer agents |
| title_full | Metallo-drugs development and action of anticancer agents edited by Astrid Sigel, Helmut Sigel, Eva Freisinger, and Roland K.O. Sigel |
| title_fullStr | Metallo-drugs development and action of anticancer agents edited by Astrid Sigel, Helmut Sigel, Eva Freisinger, and Roland K.O. Sigel |
| title_full_unstemmed | Metallo-drugs development and action of anticancer agents edited by Astrid Sigel, Helmut Sigel, Eva Freisinger, and Roland K.O. Sigel |
| title_short | Metallo-drugs |
| title_sort | metallo drugs development and action of anticancer agents |
| title_sub | development and action of anticancer agents |
| topic | Organoplatinum Compounds Antineoplastic Agents Cisplatin |
| topic_facet | Organoplatinum Compounds Antineoplastic Agents Cisplatin |
| url | https://doi.org/10.1515/9783110470734 |
| work_keys_str_mv | AT sigelastrid metallodrugsdevelopmentandactionofanticanceragents AT sigelhelmut metallodrugsdevelopmentandactionofanticanceragents AT freisingereva metallodrugsdevelopmentandactionofanticanceragents AT sigelrolandko metallodrugsdevelopmentandactionofanticanceragents |