Protein therapeutics:

In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades. Following an...

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Bibliographic Details
Other Authors: Vaughan, Tristan (Editor), Osbourn, Jane (Editor), Jallal, Bahija (Editor)
Format: Electronic eBook
Language:English
Published: Chichester, West Sussex Wiley [2017]
Series:Methods and principles in medicinal chemistry
Subjects:
Online Access:FRO01
UBG01
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Summary:In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades. Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, all currently used therapeutic protein scaffolds are surveyed, from human and non-human antibodies to antibody mimetics, bispecific antibodies and antibody-drug conjugates. This ready reference then goes on to review other key aspects such as pharmacokinetics, safety and immunogenicity, manufacture, formulation and delivery. The handbook then takes a look at current key clinical applications for protein therapeutics, from respiratory and inflammation to oncology and immune-oncology, infectious diseases and rescue therapy. Finally, several exciting prospects for the future of protein therapeutics are highlighted and discussed
Item Description:Includes bibliographical references and index
Physical Description:1 Online-Ressource (2 Bände)
ISBN:9783527699131
9783527699124

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