Protein therapeutics:
In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades. Following an...
Gespeichert in:
Weitere Verfasser: | , , |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Chichester, West Sussex
Wiley
[2017]
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Schriftenreihe: | Methods and principles in medicinal chemistry
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Schlagworte: | |
Online-Zugang: | FRO01 UBG01 Volltext |
Zusammenfassung: | In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades. Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, all currently used therapeutic protein scaffolds are surveyed, from human and non-human antibodies to antibody mimetics, bispecific antibodies and antibody-drug conjugates. This ready reference then goes on to review other key aspects such as pharmacokinetics, safety and immunogenicity, manufacture, formulation and delivery. The handbook then takes a look at current key clinical applications for protein therapeutics, from respiratory and inflammation to oncology and immune-oncology, infectious diseases and rescue therapy. Finally, several exciting prospects for the future of protein therapeutics are highlighted and discussed |
Beschreibung: | Includes bibliographical references and index |
Beschreibung: | 1 Online-Ressource (2 Bände) |
ISBN: | 9783527699131 9783527699124 |
Internformat
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520 | |a In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades. Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, all currently used therapeutic protein scaffolds are surveyed, from human and non-human antibodies to antibody mimetics, bispecific antibodies and antibody-drug conjugates. This ready reference then goes on to review other key aspects such as pharmacokinetics, safety and immunogenicity, manufacture, formulation and delivery. The handbook then takes a look at current key clinical applications for protein therapeutics, from respiratory and inflammation to oncology and immune-oncology, infectious diseases and rescue therapy. Finally, several exciting prospects for the future of protein therapeutics are highlighted and discussed | ||
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Datensatz im Suchindex
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any_adam_object | |
author2 | Vaughan, Tristan Osbourn, Jane Jallal, Bahija |
author2_role | edt edt edt |
author2_variant | t v tv j o jo b j bj |
author_facet | Vaughan, Tristan Osbourn, Jane Jallal, Bahija |
building | Verbundindex |
bvnumber | BV044642956 |
classification_rvk | VK 8560 VS 7000 VS 9400 |
collection | ZDB-35-WIC |
ctrlnum | (OCoLC)1012665732 (DE-599)BVBBV044642956 |
dewey-full | 615.3 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 615 - Pharmacology and therapeutics |
dewey-raw | 615.3 |
dewey-search | 615.3 |
dewey-sort | 3615.3 |
dewey-tens | 610 - Medicine and health |
discipline | Chemie / Pharmazie Medizin |
format | Electronic eBook |
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spelling | Protein therapeutics edited by Tristan Vaughan, Jane Osbourn, and Bahija Jallal Chichester, West Sussex Wiley [2017] 1 Online-Ressource (2 Bände) txt rdacontent c rdamedia cr rdacarrier Methods and principles in medicinal chemistry Includes bibliographical references and index Volume 1 Volume 2 In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades. Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, all currently used therapeutic protein scaffolds are surveyed, from human and non-human antibodies to antibody mimetics, bispecific antibodies and antibody-drug conjugates. This ready reference then goes on to review other key aspects such as pharmacokinetics, safety and immunogenicity, manufacture, formulation and delivery. The handbook then takes a look at current key clinical applications for protein therapeutics, from respiratory and inflammation to oncology and immune-oncology, infectious diseases and rescue therapy. Finally, several exciting prospects for the future of protein therapeutics are highlighted and discussed MEDICAL / Pharmacology / bisacsh Protein drugs / fast / (OCoLC)fst01079679 Proteins / Therapeutic use / fast / (OCoLC)fst01079767 Protein drugs Proteins / Therapeutic use Arzneimittel (DE-588)4003115-9 gnd rswk-swf Proteine (DE-588)4076388-2 gnd rswk-swf Electronic books (DE-588)4143413-4 Aufsatzsammlung gnd-content Proteine (DE-588)4076388-2 s Arzneimittel (DE-588)4003115-9 s DE-604 Vaughan, Tristan edt Osbourn, Jane edt Jallal, Bahija edt Erscheint auch als Druck-Ausgabe 3527340866 https://onlinelibrary.wiley.com/doi/book/10.1002/9783527699124 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Protein therapeutics MEDICAL / Pharmacology / bisacsh Protein drugs / fast / (OCoLC)fst01079679 Proteins / Therapeutic use / fast / (OCoLC)fst01079767 Protein drugs Proteins / Therapeutic use Arzneimittel (DE-588)4003115-9 gnd Proteine (DE-588)4076388-2 gnd |
subject_GND | (DE-588)4003115-9 (DE-588)4076388-2 (DE-588)4143413-4 |
title | Protein therapeutics |
title_auth | Protein therapeutics |
title_exact_search | Protein therapeutics |
title_full | Protein therapeutics edited by Tristan Vaughan, Jane Osbourn, and Bahija Jallal |
title_fullStr | Protein therapeutics edited by Tristan Vaughan, Jane Osbourn, and Bahija Jallal |
title_full_unstemmed | Protein therapeutics edited by Tristan Vaughan, Jane Osbourn, and Bahija Jallal |
title_short | Protein therapeutics |
title_sort | protein therapeutics |
topic | MEDICAL / Pharmacology / bisacsh Protein drugs / fast / (OCoLC)fst01079679 Proteins / Therapeutic use / fast / (OCoLC)fst01079767 Protein drugs Proteins / Therapeutic use Arzneimittel (DE-588)4003115-9 gnd Proteine (DE-588)4076388-2 gnd |
topic_facet | MEDICAL / Pharmacology / bisacsh Protein drugs / fast / (OCoLC)fst01079679 Proteins / Therapeutic use / fast / (OCoLC)fst01079767 Protein drugs Proteins / Therapeutic use Arzneimittel Proteine Aufsatzsammlung |
url | https://onlinelibrary.wiley.com/doi/book/10.1002/9783527699124 |
work_keys_str_mv | AT vaughantristan proteintherapeutics AT osbournjane proteintherapeutics AT jallalbahija proteintherapeutics |