A mathematical approach to multilevel, multiscale health interventions: pharmaceutical industry decline and policy response
This book, based on published studies, takes a unique perspective on the 30-year collapse of pharmaceutical industry productivity in the search for small molecule "magic bullet" interventions. The relentless escalation of inflation-adjusted cost per approved medicine in the United States -...
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
London
Imperial College Press
c2013
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| Schlagworte: | |
| Online-Zugang: | FHN01 Volltext |
| Zusammenfassung: | This book, based on published studies, takes a unique perspective on the 30-year collapse of pharmaceutical industry productivity in the search for small molecule "magic bullet" interventions. The relentless escalation of inflation-adjusted cost per approved medicine in the United States - from $200 million in 1950 to $1.2 billion in 2010 - has driven industry giants to, at best, slavish imitation in drug design, and at worst, abandonment of research and embracing of widespread fraud in consumer marketing. The book adapts formalism across a number of disciplines to the strategy for design of mutilevel interventions, focusing first on molecular, cellular, and larger scale examples, and then extending the argument to the simplifications provided by the dominant role of social and cultural structures and processes in individual and population patterns of health and illness. In place of "magic bullets", we must now apply "magic strategies" that act across both the scale and level of organization. This book provides an introductory roadmap to the new tools that will be needed for the design of such strategies |
| Beschreibung: | xi, 225 p. ill., maps |
| ISBN: | 9781848169975 |
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| isbn | 9781848169975 |
| language | English |
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| spelling | Wallace, Rodrick Verfasser aut A mathematical approach to multilevel, multiscale health interventions pharmaceutical industry decline and policy response Rodrick Wallace, Deborah Wallace London Imperial College Press c2013 xi, 225 p. ill., maps txt rdacontent c rdamedia cr rdacarrier This book, based on published studies, takes a unique perspective on the 30-year collapse of pharmaceutical industry productivity in the search for small molecule "magic bullet" interventions. The relentless escalation of inflation-adjusted cost per approved medicine in the United States - from $200 million in 1950 to $1.2 billion in 2010 - has driven industry giants to, at best, slavish imitation in drug design, and at worst, abandonment of research and embracing of widespread fraud in consumer marketing. The book adapts formalism across a number of disciplines to the strategy for design of mutilevel interventions, focusing first on molecular, cellular, and larger scale examples, and then extending the argument to the simplifications provided by the dominant role of social and cultural structures and processes in individual and population patterns of health and illness. In place of "magic bullets", we must now apply "magic strategies" that act across both the scale and level of organization. This book provides an introductory roadmap to the new tools that will be needed for the design of such strategies Pharmaceutical industry / United States Pharmaceutical industry / Economic aspects / United States Pharmaceutical industry / Government policy / United States Wallace, Deborah Sonstige oth Erscheint auch als Druck-Ausgabe 9781848169968 http://www.worldscientific.com/worldscibooks/10.1142/P880#t=toc Verlag URL des Erstveroeffentlichers Volltext |
| spellingShingle | Wallace, Rodrick A mathematical approach to multilevel, multiscale health interventions pharmaceutical industry decline and policy response Pharmaceutical industry / United States Pharmaceutical industry / Economic aspects / United States Pharmaceutical industry / Government policy / United States |
| title | A mathematical approach to multilevel, multiscale health interventions pharmaceutical industry decline and policy response |
| title_auth | A mathematical approach to multilevel, multiscale health interventions pharmaceutical industry decline and policy response |
| title_exact_search | A mathematical approach to multilevel, multiscale health interventions pharmaceutical industry decline and policy response |
| title_full | A mathematical approach to multilevel, multiscale health interventions pharmaceutical industry decline and policy response Rodrick Wallace, Deborah Wallace |
| title_fullStr | A mathematical approach to multilevel, multiscale health interventions pharmaceutical industry decline and policy response Rodrick Wallace, Deborah Wallace |
| title_full_unstemmed | A mathematical approach to multilevel, multiscale health interventions pharmaceutical industry decline and policy response Rodrick Wallace, Deborah Wallace |
| title_short | A mathematical approach to multilevel, multiscale health interventions |
| title_sort | a mathematical approach to multilevel multiscale health interventions pharmaceutical industry decline and policy response |
| title_sub | pharmaceutical industry decline and policy response |
| topic | Pharmaceutical industry / United States Pharmaceutical industry / Economic aspects / United States Pharmaceutical industry / Government policy / United States |
| topic_facet | Pharmaceutical industry / United States Pharmaceutical industry / Economic aspects / United States Pharmaceutical industry / Government policy / United States |
| url | http://www.worldscientific.com/worldscibooks/10.1142/P880#t=toc |
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