Development of facile metal-free synthetic approaches towards bioactive compounds: = Entwicklung einfacher, metallfreier Synthesemethoden zur Herstellung bioaktiver Verbindungen
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Abschlussarbeit Buch |
| Sprache: | English |
| Veröffentlicht: |
Erlangen ; Nürnberg
2017
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Enthält außerdem Sonderabdrucke |
| Beschreibung: | VII, 82 Seiten Illustrationen, Diagramme 21 cm |
Internformat
MARC
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| 100 | 1 | |a Held, Felix Eberhard |d 1986- |e Verfasser |0 (DE-588)1143624432 |4 aut | |
| 245 | 1 | 0 | |a Development of facile metal-free synthetic approaches towards bioactive compounds |b = Entwicklung einfacher, metallfreier Synthesemethoden zur Herstellung bioaktiver Verbindungen |c vorgelegt von Felix Eberhard Held aus Fürth |
| 246 | 1 | 3 | |a Entwicklung einfacher, metallfreier Synthesemethoden zur Herstellung bioaktiver Verbindungen |
| 246 | 1 | 1 | |a Entwicklung einfacher, metallfreier Synthesemethoden zur Herstellung bioaktiver Verbindungen |
| 264 | 1 | |a Erlangen ; Nürnberg |c 2017 | |
| 300 | |a VII, 82 Seiten |b Illustrationen, Diagramme |c 21 cm | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 500 | |a Enthält außerdem Sonderabdrucke | ||
| 502 | |b Dissertation |c Friedrich-Alexander-Universität Erlangen-Nürnberg |d 2017 | ||
| 650 | 0 | 7 | |a Bioaktive Verbindungen |0 (DE-588)4145589-7 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Chemische Synthese |0 (DE-588)4133806-6 |2 gnd |9 rswk-swf |
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| 689 | 0 | 1 | |a Chemische Synthese |0 (DE-588)4133806-6 |D s |
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Datensatz im Suchindex
| _version_ | 1804178010062979072 |
|---|---|
| adam_text | T
ABLE
OF
C
ONTENTS
ACKNOWLEDGEMENTS.............................................................................................................................................
I
LIST OF
ABBREVIATIONS............................................................................................................................................ILL
ZUSAMMENFASSUNG..............................................................................................................................................
VI
SUMMARY.............................................................................................................................................................VII
1
INTRODUCTION..................................................................................................................................................
1
1.1 CHIRAL
HOMOGENEITY............................................................................................................................
1
1.1.1 ORIGINS OF CHIRAL
HOMOGENEITY.................................................................................................1
1.1.2 ASYMMETRIC
AUTOCATALYSIS........................................................................................................
2
1.2 ENANTIOENRICHED
SYNTHESIS................................................................................................................
5
1.2.1
ORGANOCATALYSIS..........................................................................................................................
6
1.2.1.1 CHARACTERISTICS AND HISTORICAL
BACKGROUND.........................................................................6
1.2.1.2 GENERIC MODES OF
ACTIVATION................................................................................................
8
1.2.1.3 HYDROGEN BONDING
CATALYSIS................................................................................................10
1.2.1.3.1 THIOUREA
CATALYSTS........................................................................................................
10
1.2.1.3.2
BINOL-PHOSPHATES........................................................................................................
11
1.2.1.4 CHIRAL
SULFOXIDES...................................................................................................................
12
1.3 ONE-POT
REACTIONS............................................................................................................................
14
1.4 CHIRAL 1,2-AMINO
ALCOHOLS................................................................................................................
15
1.5
DOMINO-REACTIONS............................................................................................................................
18
1.6
QUINAZOLINES......................................................................................................................................20
2 MOTIVATION AND
GOALS...............................................................................................................................
22
3
RESULTS........................................................................................................................................................
25
3.1 INSIGHTS INTO THE SPONTANEOUS EMERGENCE OF ENANTIOSELECTIVITY IN AN
ASYMMETRIC
MANNICH REACTION CARRIED OUT WITHOUT EXTERNAL CATALYST
.......................................................................
25
3.2 SYNTHESIS OF ARMODAFINIL* VIA ORGANO- AND NON-HERNE IRON-CATALYZED
SULFIDE OXIDATION
USING HYDROGEN PEROXIDE AS ENVIRONMENTALLY BENIGN
OXIDANT...............................................................35
3.3 ONE-POT ROUTE TO SS-ADRENERGIC BLOCKERS VIA ENANTIOSELECTIVE
ORGANOCATALYSED
EPOXIDATION OF TERMINAL ALKENES AS A KEY
STEP..........................................................................................
47
3.4 FACILE ACCESS TO NEW CLASS OF POTENT ANTIVIRAL QUINAZOLINE
HETEROCYCLES WITH
FLUORESCENCE PROPERTIES VIA MERGING METAL-FREE DOMINO
REACTIONS........................................................56
4 BIBLIOGRAPHY AND
APPENDIX.....................................................................................................................
70
|
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| indexdate | 2024-07-10T07:57:10Z |
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| language | English |
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| physical | VII, 82 Seiten Illustrationen, Diagramme 21 cm |
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| spelling | Held, Felix Eberhard 1986- Verfasser (DE-588)1143624432 aut Development of facile metal-free synthetic approaches towards bioactive compounds = Entwicklung einfacher, metallfreier Synthesemethoden zur Herstellung bioaktiver Verbindungen vorgelegt von Felix Eberhard Held aus Fürth Entwicklung einfacher, metallfreier Synthesemethoden zur Herstellung bioaktiver Verbindungen Erlangen ; Nürnberg 2017 VII, 82 Seiten Illustrationen, Diagramme 21 cm txt rdacontent n rdamedia nc rdacarrier Enthält außerdem Sonderabdrucke Dissertation Friedrich-Alexander-Universität Erlangen-Nürnberg 2017 Bioaktive Verbindungen (DE-588)4145589-7 gnd rswk-swf Chemische Synthese (DE-588)4133806-6 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Bioaktive Verbindungen (DE-588)4145589-7 s Chemische Synthese (DE-588)4133806-6 s DE-604 DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030002029&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Held, Felix Eberhard 1986- Development of facile metal-free synthetic approaches towards bioactive compounds = Entwicklung einfacher, metallfreier Synthesemethoden zur Herstellung bioaktiver Verbindungen Bioaktive Verbindungen (DE-588)4145589-7 gnd Chemische Synthese (DE-588)4133806-6 gnd |
| subject_GND | (DE-588)4145589-7 (DE-588)4133806-6 (DE-588)4113937-9 |
| title | Development of facile metal-free synthetic approaches towards bioactive compounds = Entwicklung einfacher, metallfreier Synthesemethoden zur Herstellung bioaktiver Verbindungen |
| title_alt | Entwicklung einfacher, metallfreier Synthesemethoden zur Herstellung bioaktiver Verbindungen |
| title_auth | Development of facile metal-free synthetic approaches towards bioactive compounds = Entwicklung einfacher, metallfreier Synthesemethoden zur Herstellung bioaktiver Verbindungen |
| title_exact_search | Development of facile metal-free synthetic approaches towards bioactive compounds = Entwicklung einfacher, metallfreier Synthesemethoden zur Herstellung bioaktiver Verbindungen |
| title_full | Development of facile metal-free synthetic approaches towards bioactive compounds = Entwicklung einfacher, metallfreier Synthesemethoden zur Herstellung bioaktiver Verbindungen vorgelegt von Felix Eberhard Held aus Fürth |
| title_fullStr | Development of facile metal-free synthetic approaches towards bioactive compounds = Entwicklung einfacher, metallfreier Synthesemethoden zur Herstellung bioaktiver Verbindungen vorgelegt von Felix Eberhard Held aus Fürth |
| title_full_unstemmed | Development of facile metal-free synthetic approaches towards bioactive compounds = Entwicklung einfacher, metallfreier Synthesemethoden zur Herstellung bioaktiver Verbindungen vorgelegt von Felix Eberhard Held aus Fürth |
| title_short | Development of facile metal-free synthetic approaches towards bioactive compounds |
| title_sort | development of facile metal free synthetic approaches towards bioactive compounds entwicklung einfacher metallfreier synthesemethoden zur herstellung bioaktiver verbindungen |
| title_sub | = Entwicklung einfacher, metallfreier Synthesemethoden zur Herstellung bioaktiver Verbindungen |
| topic | Bioaktive Verbindungen (DE-588)4145589-7 gnd Chemische Synthese (DE-588)4133806-6 gnd |
| topic_facet | Bioaktive Verbindungen Chemische Synthese Hochschulschrift |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030002029&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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