Metabolism and bacterial pathogenesis:
In the 1980's, Rolf Freter, a true pioneer in the field of intestinal colonization, concluded that although several factors could theoretically contribute to a microorganism's ability to colonize the intestinal ecosystem, effective competition for nutrients is paramount to success. Freter...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Washington, DC
ASM Press
[2015]
|
| Schlagworte: | |
| Zusammenfassung: | In the 1980's, Rolf Freter, a true pioneer in the field of intestinal colonization, concluded that although several factors could theoretically contribute to a microorganism's ability to colonize the intestinal ecosystem, effective competition for nutrients is paramount to success. Freter considered this concept to apply equally to bacterial commensals and pathogens. He considered nutrient acquisition to be as critical for the success of a bacterial pathogen in its host as its ability to produce virulence factors. Despite the general acceptance of Freter's ideas, until recently, metabolism and bacterial pathogenesis were considered to be two distinctly different fields of study. Even the title of this book: Metabolism and Bacterial Pathogenesis might be interpreted as meaning that these fields are separate entities. Nothing could be further from the truth. There is no doubt that the discovery of pathogen-specific virulence factors such as fimbriae that allow adhesion to mucosal surface receptors, secreted toxins, iron acquisition systems, motility, mechanisms geared to avoid immune responses etc., have been instrumental in understanding bacterial pathogenesis and in some instances in devising ways to interfere with the pathogenic process. Nevertheless, it is becoming increasingly clear that bacterial metabolism, while not a virulence factor per se, is essential for pathogenesis and that interfering with pathogen specific metabolic pathways used during infection might lead to effective treatments |
| Beschreibung: | Description based on print version record |
| Beschreibung: | 1 online resource (395 pages) illustrations |
| ISBN: | 9781555818883 |
Internformat
MARC
| LEADER | 00000nmm a2200000zc 4500 | ||
|---|---|---|---|
| 001 | BV044571372 | ||
| 003 | DE-604 | ||
| 005 | 00000000000000.0 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 171103s2015 |||| o||u| ||||||eng d | ||
| 020 | |a 9781555818883 |c ebook |9 978-1-55581-888-3 | ||
| 035 | |a (ZDB-30-PAD)EBC4392500 | ||
| 035 | |a (ZDB-89-EBL)EBL4392500 | ||
| 035 | |a (ZDB-38-EBR)ebr11160636 | ||
| 035 | |a (OCoLC)926706084 | ||
| 035 | |a (DE-599)BVBBV044571372 | ||
| 040 | |a DE-604 |b ger |e rda | ||
| 041 | 0 | |a eng | |
| 082 | 0 | |a 572/.429 |2 23 | |
| 084 | |a WF 5200 |0 (DE-625)148380: |2 rvk | ||
| 245 | 1 | 0 | |a Metabolism and bacterial pathogenesis |c edited by Tyrrell Conway, Paul S. Cohen |
| 264 | 1 | |a Washington, DC |b ASM Press |c [2015] | |
| 264 | 4 | |c © 2015 | |
| 300 | |a 1 online resource (395 pages) |b illustrations | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 500 | |a Description based on print version record | ||
| 520 | |a In the 1980's, Rolf Freter, a true pioneer in the field of intestinal colonization, concluded that although several factors could theoretically contribute to a microorganism's ability to colonize the intestinal ecosystem, effective competition for nutrients is paramount to success. Freter considered this concept to apply equally to bacterial commensals and pathogens. He considered nutrient acquisition to be as critical for the success of a bacterial pathogen in its host as its ability to produce virulence factors. Despite the general acceptance of Freter's ideas, until recently, metabolism and bacterial pathogenesis were considered to be two distinctly different fields of study. Even the title of this book: Metabolism and Bacterial Pathogenesis might be interpreted as meaning that these fields are separate entities. Nothing could be further from the truth. There is no doubt that the discovery of pathogen-specific virulence factors such as fimbriae that allow adhesion to mucosal surface receptors, secreted toxins, iron acquisition systems, motility, mechanisms geared to avoid immune responses etc., have been instrumental in understanding bacterial pathogenesis and in some instances in devising ways to interfere with the pathogenic process. Nevertheless, it is becoming increasingly clear that bacterial metabolism, while not a virulence factor per se, is essential for pathogenesis and that interfering with pathogen specific metabolic pathways used during infection might lead to effective treatments | ||
| 650 | 4 | |a Microbial metabolism | |
| 650 | 4 | |a Pathogenic bacteria | |
| 650 | 4 | |a Virulence (Microbiology) | |
| 650 | 0 | 7 | |a Virulenz |0 (DE-588)4129834-2 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Metabolismus |0 (DE-588)4169554-9 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Bakterien |0 (DE-588)4004296-0 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Bakterien |0 (DE-588)4004296-0 |D s |
| 689 | 0 | 1 | |a Metabolismus |0 (DE-588)4169554-9 |D s |
| 689 | 0 | 2 | |a Virulenz |0 (DE-588)4129834-2 |D s |
| 689 | 0 | |8 1\p |5 DE-604 | |
| 700 | 1 | |a Cohen, Paul S. |d 1939- |4 edt | |
| 700 | 1 | |a Conway, Tyrrell |4 edt | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |t Metabolism and bacterial pathogenesis |d Washington, DC : ASM Press, [2015] |z 9781555818869 |
| 912 | |a ZDB-30-PAD | ||
| 999 | |a oai:aleph.bib-bvb.de:BVB01-029969896 | ||
| 883 | 1 | |8 1\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
Datensatz im Suchindex
| _version_ | 1804177951349014528 |
|---|---|
| any_adam_object | |
| author2 | Cohen, Paul S. 1939- Conway, Tyrrell |
| author2_role | edt edt |
| author2_variant | p s c ps psc t c tc |
| author_facet | Cohen, Paul S. 1939- Conway, Tyrrell |
| building | Verbundindex |
| bvnumber | BV044571372 |
| classification_rvk | WF 5200 |
| collection | ZDB-30-PAD |
| ctrlnum | (ZDB-30-PAD)EBC4392500 (ZDB-89-EBL)EBL4392500 (ZDB-38-EBR)ebr11160636 (OCoLC)926706084 (DE-599)BVBBV044571372 |
| dewey-full | 572/.429 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 572 - Biochemistry |
| dewey-raw | 572/.429 |
| dewey-search | 572/.429 |
| dewey-sort | 3572 3429 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03324nmm a2200505zc 4500</leader><controlfield tag="001">BV044571372</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">171103s2015 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781555818883</subfield><subfield code="c">ebook</subfield><subfield code="9">978-1-55581-888-3</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-30-PAD)EBC4392500</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-89-EBL)EBL4392500</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-38-EBR)ebr11160636</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)926706084</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV044571372</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">572/.429</subfield><subfield code="2">23</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WF 5200</subfield><subfield code="0">(DE-625)148380:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Metabolism and bacterial pathogenesis</subfield><subfield code="c">edited by Tyrrell Conway, Paul S. Cohen</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Washington, DC</subfield><subfield code="b">ASM Press</subfield><subfield code="c">[2015]</subfield></datafield><datafield tag="264" ind1=" " ind2="4"><subfield code="c">© 2015</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 online resource (395 pages)</subfield><subfield code="b">illustrations</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Description based on print version record</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">In the 1980's, Rolf Freter, a true pioneer in the field of intestinal colonization, concluded that although several factors could theoretically contribute to a microorganism's ability to colonize the intestinal ecosystem, effective competition for nutrients is paramount to success. Freter considered this concept to apply equally to bacterial commensals and pathogens. He considered nutrient acquisition to be as critical for the success of a bacterial pathogen in its host as its ability to produce virulence factors. Despite the general acceptance of Freter's ideas, until recently, metabolism and bacterial pathogenesis were considered to be two distinctly different fields of study. Even the title of this book: Metabolism and Bacterial Pathogenesis might be interpreted as meaning that these fields are separate entities. Nothing could be further from the truth. There is no doubt that the discovery of pathogen-specific virulence factors such as fimbriae that allow adhesion to mucosal surface receptors, secreted toxins, iron acquisition systems, motility, mechanisms geared to avoid immune responses etc., have been instrumental in understanding bacterial pathogenesis and in some instances in devising ways to interfere with the pathogenic process. Nevertheless, it is becoming increasingly clear that bacterial metabolism, while not a virulence factor per se, is essential for pathogenesis and that interfering with pathogen specific metabolic pathways used during infection might lead to effective treatments</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Microbial metabolism</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pathogenic bacteria</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Virulence (Microbiology)</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Virulenz</subfield><subfield code="0">(DE-588)4129834-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Metabolismus</subfield><subfield code="0">(DE-588)4169554-9</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Bakterien</subfield><subfield code="0">(DE-588)4004296-0</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Bakterien</subfield><subfield code="0">(DE-588)4004296-0</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Metabolismus</subfield><subfield code="0">(DE-588)4169554-9</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="2"><subfield code="a">Virulenz</subfield><subfield code="0">(DE-588)4129834-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="8">1\p</subfield><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cohen, Paul S.</subfield><subfield code="d">1939-</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Conway, Tyrrell</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="t">Metabolism and bacterial pathogenesis</subfield><subfield code="d">Washington, DC : ASM Press, [2015]</subfield><subfield code="z">9781555818869</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-30-PAD</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-029969896</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">1\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield></record></collection> |
| id | DE-604.BV044571372 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T07:56:14Z |
| institution | BVB |
| isbn | 9781555818883 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-029969896 |
| oclc_num | 926706084 |
| open_access_boolean | |
| physical | 1 online resource (395 pages) illustrations |
| psigel | ZDB-30-PAD |
| publishDate | 2015 |
| publishDateSearch | 2015 |
| publishDateSort | 2015 |
| publisher | ASM Press |
| record_format | marc |
| spelling | Metabolism and bacterial pathogenesis edited by Tyrrell Conway, Paul S. Cohen Washington, DC ASM Press [2015] © 2015 1 online resource (395 pages) illustrations txt rdacontent c rdamedia cr rdacarrier Description based on print version record In the 1980's, Rolf Freter, a true pioneer in the field of intestinal colonization, concluded that although several factors could theoretically contribute to a microorganism's ability to colonize the intestinal ecosystem, effective competition for nutrients is paramount to success. Freter considered this concept to apply equally to bacterial commensals and pathogens. He considered nutrient acquisition to be as critical for the success of a bacterial pathogen in its host as its ability to produce virulence factors. Despite the general acceptance of Freter's ideas, until recently, metabolism and bacterial pathogenesis were considered to be two distinctly different fields of study. Even the title of this book: Metabolism and Bacterial Pathogenesis might be interpreted as meaning that these fields are separate entities. Nothing could be further from the truth. There is no doubt that the discovery of pathogen-specific virulence factors such as fimbriae that allow adhesion to mucosal surface receptors, secreted toxins, iron acquisition systems, motility, mechanisms geared to avoid immune responses etc., have been instrumental in understanding bacterial pathogenesis and in some instances in devising ways to interfere with the pathogenic process. Nevertheless, it is becoming increasingly clear that bacterial metabolism, while not a virulence factor per se, is essential for pathogenesis and that interfering with pathogen specific metabolic pathways used during infection might lead to effective treatments Microbial metabolism Pathogenic bacteria Virulence (Microbiology) Virulenz (DE-588)4129834-2 gnd rswk-swf Metabolismus (DE-588)4169554-9 gnd rswk-swf Bakterien (DE-588)4004296-0 gnd rswk-swf Bakterien (DE-588)4004296-0 s Metabolismus (DE-588)4169554-9 s Virulenz (DE-588)4129834-2 s 1\p DE-604 Cohen, Paul S. 1939- edt Conway, Tyrrell edt Erscheint auch als Druck-Ausgabe Metabolism and bacterial pathogenesis Washington, DC : ASM Press, [2015] 9781555818869 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Metabolism and bacterial pathogenesis Microbial metabolism Pathogenic bacteria Virulence (Microbiology) Virulenz (DE-588)4129834-2 gnd Metabolismus (DE-588)4169554-9 gnd Bakterien (DE-588)4004296-0 gnd |
| subject_GND | (DE-588)4129834-2 (DE-588)4169554-9 (DE-588)4004296-0 |
| title | Metabolism and bacterial pathogenesis |
| title_auth | Metabolism and bacterial pathogenesis |
| title_exact_search | Metabolism and bacterial pathogenesis |
| title_full | Metabolism and bacterial pathogenesis edited by Tyrrell Conway, Paul S. Cohen |
| title_fullStr | Metabolism and bacterial pathogenesis edited by Tyrrell Conway, Paul S. Cohen |
| title_full_unstemmed | Metabolism and bacterial pathogenesis edited by Tyrrell Conway, Paul S. Cohen |
| title_short | Metabolism and bacterial pathogenesis |
| title_sort | metabolism and bacterial pathogenesis |
| topic | Microbial metabolism Pathogenic bacteria Virulence (Microbiology) Virulenz (DE-588)4129834-2 gnd Metabolismus (DE-588)4169554-9 gnd Bakterien (DE-588)4004296-0 gnd |
| topic_facet | Microbial metabolism Pathogenic bacteria Virulence (Microbiology) Virulenz Metabolismus Bakterien |
| work_keys_str_mv | AT cohenpauls metabolismandbacterialpathogenesis AT conwaytyrrell metabolismandbacterialpathogenesis |