Genomic mosaicism in neurons and other cell types:
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Schriftenreihe: | Neuromethods
131 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | xvi, 382 Seiten Illustrationen |
| ISBN: | 9781493972791 |
Internformat
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Datensatz im Suchindex
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Contents
Preface to the Series. v
Preface. vii
Contributors. xiii
Part I Introduction
1 Principles and Approaches for Discovery and Validation of Somatic
Mosaicism in the Human Brain. 3
Alexej Abyzov, Alexander E. Urban, and Flora M. Vaccarino
Part II Aneuploidy and Ploidy Variation
2 FISH-Based Assays for Detecting Genomic (Chromosomal)
Mosaicism in Human Brain Cells. 27
Yuri B. Yurov, Svetlana G. Vorsanova, Ilia K Soloviev,
Alexei M. Ratnikov, and Ivan Y lourov
3 Flow Cytometric and Sorting Analyses for Nuclear DNA Content,
Nucleotide Sequencing, and Interphase FISH. 43
Gwendolyn E. Kaeser and Jerold Chun
4 Flow Cytometric Quantification, Isolation, and Subsequent
Epigenetic Analysis of Tetraploid Neurons. 57
Noelia Lopez-Sanchez, Iris Patino-Parrado, and José Maria Frade
5 A Cytomic Approach Towards Genomic Individuality of Neurons. 81
Thomas Arendt, Birgit Belter, Martina K. Brückner,
Uwe Ueberham, Markus Morawski, and Attila Tarnok
Part III DNA Copy Number Variation
6 Single-Cell CNV Detection in Human Neuronal Nuclei. 109
Margaret B. Wierman, Ian E. Burbulis, William D. Chronister,
Stefan Bekiranov, and Michael J. McConnell
7 Multiple Annealing and Looping-Based Amplification Cycles
(MALBAC) for the Analysis of DNA Copy Number Variation. 133
Chenghang Zong
8 Competitive PCR for Copy Number Assessment by Restricting dNTPs. 143
Laming Zhou, Robert A, Palais, Yotam Ardon, and Carl T. Wittwer
9 Using Cloning to Amplify Neuronal Genomes for Whole-Genome
Sequencing and Comprehensive Mutation Detection and Validation. 163
Jennifer L. Hazen, Michael Æ Duran, Ryan P. Smith,
Alberto ft. Rodriguez, Greg S. Martin, Sergey Kupriyanov, Ira M. Hall,
and Kristin K. Baldwin
Xi
xii
Contents
Part IV LINE-1 Retrotransposition
10 Analysis of LINE-1 Retrotransposition
in Neural Progenitor Cells and Neurons. 189
Angela Macia andAlysson R. Muotri
11 Estimation of LINE-1 Copy Number in the Brain
Tissue and Isolated Neuronal Nuclei. 209
Miki BundOy Tadafumi Kato, and Kazuya Iwamoto
12 Analysis of Somatic LINE-1 Insertions in Neurons. 219
Franciscoja Sanchez-Luqtte, Sandra R. Richardson,
and Geoffrey J. Faulkner
13 Single-Cell Whole Genome Amplification and Sequencing
to Study Neuronal Mosaicism and Diversity. 253
Patrick J, Reedy Meiyan Wang, Jennifer A. Erwin,
Apua C. M. Paquola, and Fred H. Gage
Part V Genetic and Genomic Mosaicism in Aging and Disease
14 FISH Analysis of Aging-Associated Aneuploidy in Neurons
and Nonneuronal Brain Cells. 271
Grasiella A. Andriani and Cristina Montagna
15 Genomic Analysis and In Vivo Functional Validation
of Brain Somatic Mutations Leading to Focal Cortical Malformations. 299
Joe Seok Lim and Jeong Ho Lee
16 Using Fluorescence In Situ Hybridization (FISH) Analysis
to Measure Chromosome Instability and Mosaic Aneuploidy
in Neurodegenerative Diseases. 329
Julbert CaneuSy Antoneta Granic, Heidi ƒ. Chialy
and Huntington Potter
17 Identification of Low Allele Frequency Mosaic Mutations
in Alzheimer Disease. 361
Carlo Sala Frigerio9 Mark FierSy Thierry Vo et y
and Bart De Strooper
Index
379 |
| any_adam_object | 1 |
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| building | Verbundindex |
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| callnumber-first | R - Medicine |
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| ctrlnum | (OCoLC)1010940090 (DE-599)BVBBV044551256 |
| dewey-full | 612.8 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 612 - Human physiology |
| dewey-raw | 612.8 |
| dewey-search | 612.8 |
| dewey-sort | 3612.8 |
| dewey-tens | 610 - Medicine and health |
| discipline | Biologie Medizin |
| format | Book |
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| indexdate | 2024-12-06T17:00:49Z |
| institution | BVB |
| isbn | 9781493972791 |
| language | English |
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| spelling | Frade, José María edt Genomic mosaicism in neurons and other cell types editors: José María Frade, Fred H. Gage New York, NY Humana Press [2017] xvi, 382 Seiten Illustrationen txt rdacontent n rdamedia nc rdacarrier Neuromethods 131 Springer protocols Medizin Genetische Variabilität (DE-588)4264352-1 gnd rswk-swf Genanalyse (DE-588)4200230-8 gnd rswk-swf Nervenzelle (DE-588)4041649-5 gnd rswk-swf Medicine Neurosciences Biomedicine (DE-588)4143413-4 Aufsatzsammlung gnd-content Nervenzelle (DE-588)4041649-5 s Genanalyse (DE-588)4200230-8 s Genetische Variabilität (DE-588)4264352-1 s DE-604 Gage, Fred 1950- (DE-588)1089168462 edt Erscheint auch als Online-Ausgabe 978-1-4939-7280-7 Neuromethods 131 (DE-604)BV008920602 131 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029950106&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Genomic mosaicism in neurons and other cell types Neuromethods Medizin Genetische Variabilität (DE-588)4264352-1 gnd Genanalyse (DE-588)4200230-8 gnd Nervenzelle (DE-588)4041649-5 gnd |
| subject_GND | (DE-588)4264352-1 (DE-588)4200230-8 (DE-588)4041649-5 (DE-588)4143413-4 |
| title | Genomic mosaicism in neurons and other cell types |
| title_auth | Genomic mosaicism in neurons and other cell types |
| title_exact_search | Genomic mosaicism in neurons and other cell types |
| title_full | Genomic mosaicism in neurons and other cell types editors: José María Frade, Fred H. Gage |
| title_fullStr | Genomic mosaicism in neurons and other cell types editors: José María Frade, Fred H. Gage |
| title_full_unstemmed | Genomic mosaicism in neurons and other cell types editors: José María Frade, Fred H. Gage |
| title_short | Genomic mosaicism in neurons and other cell types |
| title_sort | genomic mosaicism in neurons and other cell types |
| topic | Medizin Genetische Variabilität (DE-588)4264352-1 gnd Genanalyse (DE-588)4200230-8 gnd Nervenzelle (DE-588)4041649-5 gnd |
| topic_facet | Medizin Genetische Variabilität Genanalyse Nervenzelle Aufsatzsammlung |
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