The CRISPR/Cas system: emerging technology and application
The use of CRISPR/Cas technology for genome editing suggests many potential applications, including the alteration of the germline of humans, animals and food crops. The speed and efficiency of the CRISPR/Cas system make it a potentially useful system for gene therapy. In this volume expert internat...
Gespeichert in:
| Weitere Verfasser: | |
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| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Norfolk, UK
Caister Academic Press
[2017]
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Zusammenfassung: | The use of CRISPR/Cas technology for genome editing suggests many potential applications, including the alteration of the germline of humans, animals and food crops. The speed and efficiency of the CRISPR/Cas system make it a potentially useful system for gene therapy. In this volume expert international authors provide a useful and timely review of the applications of the CRISPR/Cas system across diverse fields and explore further avenues and research directions of this novel and powerful editing technology. The technology and its application are reviewed with respect to reproduction and development, immunity and genetic diseases, system structure and system specificity. Some of the potential problems of the CRISPR/Cas system are also discussed, in particular the specificity of the system: this remains an important topic as improvement could lead to the more direct and efficient use of the CRISPR/Cas system in clinical settings. The authors also debate ethical concerns associated with this powerful new technology. This volume is a rigorous review of the applications and new opportunities for the CRISPR/Cas system and provides a stimulus for current and future research. An invaluable guide for all scientists working in the fields of genome editing and gene therapy the book is also recommended for all life sciences libraries |
| Beschreibung: | 112 Seiten Illustrationen |
| ISBN: | 9781910190630 1910190632 |
Internformat
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| 245 | 1 | 0 | |a The CRISPR/Cas system |b emerging technology and application |c edited by Muhammad Jamal, State Key Laboratory of Agricultural Microbiology, College of Animal Science and Medicine, Huazhong Agricultural University, Wuhan, The People's Republic of China |
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| 505 | 8 | |a Type III CRISPR/Cas system: introduction and its application for genetic manipulations -- dCas9: a versatile tool for epigenome editing -- Treating genetic disorders using state-of-the-art technology -- An era of CRISPR/cas9-mediated plant genome editing -- CRISPR/Cas9-mediated immunity in plants against pathogens -- Improving CRISPR/Cas9 on-target specificity -- CRISPR-mediated genome engineering and its application in industry -- Applications of CRISRP/Cas9 in reproductive biology -- Ethical issues regarding CRISPR-mediated genome editing | |
| 520 | 3 | |a The use of CRISPR/Cas technology for genome editing suggests many potential applications, including the alteration of the germline of humans, animals and food crops. The speed and efficiency of the CRISPR/Cas system make it a potentially useful system for gene therapy. In this volume expert international authors provide a useful and timely review of the applications of the CRISPR/Cas system across diverse fields and explore further avenues and research directions of this novel and powerful editing technology. The technology and its application are reviewed with respect to reproduction and development, immunity and genetic diseases, system structure and system specificity. Some of the potential problems of the CRISPR/Cas system are also discussed, in particular the specificity of the system: this remains an important topic as improvement could lead to the more direct and efficient use of the CRISPR/Cas system in clinical settings. The authors also debate ethical concerns associated with this powerful new technology. This volume is a rigorous review of the applications and new opportunities for the CRISPR/Cas system and provides a stimulus for current and future research. An invaluable guide for all scientists working in the fields of genome editing and gene therapy the book is also recommended for all life sciences libraries | |
| 650 | 0 | 7 | |a CRISPR/Cas-Methode |0 (DE-588)1116100770 |2 gnd |9 rswk-swf |
| 653 | 0 | |a CRISPR-Cas Systems | |
| 653 | 0 | |a Gene Editing / methods | |
| 653 | 0 | |a Gene Transfer Techniques | |
| 653 | 0 | |a Genetic engineering | |
| 653 | 0 | |a Gene therapy | |
| 653 | 0 | |a Molecular genetics | |
| 653 | 0 | |a RNA editing | |
| 653 | 0 | |a Prokaryotes | |
| 653 | 0 | |a Gene therapy | |
| 653 | 0 | |a Genetic engineering | |
| 653 | 0 | |a Molecular genetics | |
| 653 | 0 | |a Prokaryotes | |
| 653 | 0 | |a RNA editing | |
| 655 | 7 | |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
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Datensatz im Suchindex
| _version_ | 1804177897036972032 |
|---|---|
| adam_text | Dedication v
Preface vii
1 Type 111 CRISPR/Cas System: Introduction and its Application for
Genetic Manipulations 1
Tao Liu, Saifu Pan, Yingjun Li, Nan Peng and Qunxin She
2 dCas9: A Versatile Tool For Epigenome Editing 15
Daan J.W. Brocken, Mariliis Tark֊Dame and Remus T. Dame
3 Treating Genetic Disorders Using State-of-the-Art Technology 33
Muhammad Jamal, Arif Ullah, Muhammad Ahsan Naeem, Rohit Tyagi, Zeshan
Habib, Faheem Ahmad Khan and Khaista Rehman
4 An Era of CRISPR/Cas9-mediated Plant Genome Editing 47
Haris Khurshid, Sohail Ahmad Jan, Zabta Khan Shinwari, Muhammad Jamal and
Sabir Hussain Shah
5 CRISPR/Cas9-mediated Immunity in Plants Against Pathogens 55
Muhammad Sameeullah, Faheem Ahmed Khan, Goksel Ozer, Noreen Aslam,
Ekrem Gurel, Mohammad Tahir Waheed and Turan Karadeniz
6 Improving CRISPR/Cas9 On-target Specificity 65
Muhammad Jamal, Arif Ullah, Muhammad Ahsan Naeem, Rohit Tyagi, Zeshan
Habib and Khaista Rehman
7 CRISPR-mediated Genome Engineering and its Application in Industry 81
Saeed Kaboli and Hasan Babazada
8 Applications of CRISPR/Cas9 in Reproductive Biology 93
Faheem Ahmed Khan, Nuruliarizki Shinta Pandupuspitasari, Huang ChunJie,
Hafiz Ishfaq Ahmad, Kai Wang, Muhammad Jamil Ahmad and ShuJun Zhang
9 Ethical Issues Regarding CRISPR-mediated Genome Editing 103
Zabta Khan Shinwari, Faouzia Tanveer and Ali Talha Khalil
Index
111
|
| any_adam_object | 1 |
| author2 | Jamal, Muhammad |
| author2_role | edt |
| author2_variant | m j mj |
| author_facet | Jamal, Muhammad |
| building | Verbundindex |
| bvnumber | BV044539546 |
| classification_rvk | WC 4460 |
| contents | Type III CRISPR/Cas system: introduction and its application for genetic manipulations -- dCas9: a versatile tool for epigenome editing -- Treating genetic disorders using state-of-the-art technology -- An era of CRISPR/cas9-mediated plant genome editing -- CRISPR/Cas9-mediated immunity in plants against pathogens -- Improving CRISPR/Cas9 on-target specificity -- CRISPR-mediated genome engineering and its application in industry -- Applications of CRISRP/Cas9 in reproductive biology -- Ethical issues regarding CRISPR-mediated genome editing |
| ctrlnum | (OCoLC)1013585001 (DE-599)BVBBV044539546 |
| discipline | Biologie |
| format | Book |
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| spelling | The CRISPR/Cas system emerging technology and application edited by Muhammad Jamal, State Key Laboratory of Agricultural Microbiology, College of Animal Science and Medicine, Huazhong Agricultural University, Wuhan, The People's Republic of China Norfolk, UK Caister Academic Press [2017] 112 Seiten Illustrationen txt rdacontent n rdamedia nc rdacarrier Type III CRISPR/Cas system: introduction and its application for genetic manipulations -- dCas9: a versatile tool for epigenome editing -- Treating genetic disorders using state-of-the-art technology -- An era of CRISPR/cas9-mediated plant genome editing -- CRISPR/Cas9-mediated immunity in plants against pathogens -- Improving CRISPR/Cas9 on-target specificity -- CRISPR-mediated genome engineering and its application in industry -- Applications of CRISRP/Cas9 in reproductive biology -- Ethical issues regarding CRISPR-mediated genome editing The use of CRISPR/Cas technology for genome editing suggests many potential applications, including the alteration of the germline of humans, animals and food crops. The speed and efficiency of the CRISPR/Cas system make it a potentially useful system for gene therapy. In this volume expert international authors provide a useful and timely review of the applications of the CRISPR/Cas system across diverse fields and explore further avenues and research directions of this novel and powerful editing technology. The technology and its application are reviewed with respect to reproduction and development, immunity and genetic diseases, system structure and system specificity. Some of the potential problems of the CRISPR/Cas system are also discussed, in particular the specificity of the system: this remains an important topic as improvement could lead to the more direct and efficient use of the CRISPR/Cas system in clinical settings. The authors also debate ethical concerns associated with this powerful new technology. This volume is a rigorous review of the applications and new opportunities for the CRISPR/Cas system and provides a stimulus for current and future research. An invaluable guide for all scientists working in the fields of genome editing and gene therapy the book is also recommended for all life sciences libraries CRISPR/Cas-Methode (DE-588)1116100770 gnd rswk-swf CRISPR-Cas Systems Gene Editing / methods Gene Transfer Techniques Genetic engineering Gene therapy Molecular genetics RNA editing Prokaryotes (DE-588)4143413-4 Aufsatzsammlung gnd-content CRISPR/Cas-Methode (DE-588)1116100770 s DE-604 Jamal, Muhammad edt Erscheint auch als Online-Ausgabe 978-1-910190-64-7 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029938647&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | The CRISPR/Cas system emerging technology and application Type III CRISPR/Cas system: introduction and its application for genetic manipulations -- dCas9: a versatile tool for epigenome editing -- Treating genetic disorders using state-of-the-art technology -- An era of CRISPR/cas9-mediated plant genome editing -- CRISPR/Cas9-mediated immunity in plants against pathogens -- Improving CRISPR/Cas9 on-target specificity -- CRISPR-mediated genome engineering and its application in industry -- Applications of CRISRP/Cas9 in reproductive biology -- Ethical issues regarding CRISPR-mediated genome editing CRISPR/Cas-Methode (DE-588)1116100770 gnd |
| subject_GND | (DE-588)1116100770 (DE-588)4143413-4 |
| title | The CRISPR/Cas system emerging technology and application |
| title_auth | The CRISPR/Cas system emerging technology and application |
| title_exact_search | The CRISPR/Cas system emerging technology and application |
| title_full | The CRISPR/Cas system emerging technology and application edited by Muhammad Jamal, State Key Laboratory of Agricultural Microbiology, College of Animal Science and Medicine, Huazhong Agricultural University, Wuhan, The People's Republic of China |
| title_fullStr | The CRISPR/Cas system emerging technology and application edited by Muhammad Jamal, State Key Laboratory of Agricultural Microbiology, College of Animal Science and Medicine, Huazhong Agricultural University, Wuhan, The People's Republic of China |
| title_full_unstemmed | The CRISPR/Cas system emerging technology and application edited by Muhammad Jamal, State Key Laboratory of Agricultural Microbiology, College of Animal Science and Medicine, Huazhong Agricultural University, Wuhan, The People's Republic of China |
| title_short | The CRISPR/Cas system |
| title_sort | the crispr cas system emerging technology and application |
| title_sub | emerging technology and application |
| topic | CRISPR/Cas-Methode (DE-588)1116100770 gnd |
| topic_facet | CRISPR/Cas-Methode Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029938647&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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