Nonmotor Parkinson's: The hidden face: the many hidden faces
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Cambridge, MA
Academic Press
2017
|
| Ausgabe: | First edition |
| Schriftenreihe: | International review of neurobiology
volume 133 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | xxv, 768 Seiten Illustrationen |
| ISBN: | 9780128137086 |
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| 245 | 1 | 0 | |a Nonmotor Parkinson's: The hidden face |b the many hidden faces |c edited by K. Ray Chaudhuri, Nataliya Titova |
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Datensatz im Suchindex
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| adam_text | CONTENTS
Contributors xi ii
Prefaces by Günther Deuschi and Christopher G. Goetz xix
The Editors Words xxiii
Section 1
Nonmotor Symptoms: The Hidden Face
of Parkinson s
1. The Status of Nonmotor Features of the Malady
in an Essay on the Shaking Palsy (1817) 3
Brian Hurwitz
1. introduction 3
2. Clinical Features of the Shaking Palsy 6
3. Nonmotor Components of the Shaking Palsy 8
4. Conclusion 11
References 11
2. Neuropathology of Nonmotor Symptoms
of Parkinson s Disease 13
Kurt A. Jeilinger
1. Introduction 15
2. Preclinical PD 17
3. Parkinson s Disease 18
4. Orcadian System Disorders 21
5. Olfactory Dysfunction/Hyposmia 22
6. Autonomic Dysfunction 23
7. Visual Dysfunctions 27
8. Sensory Disturbances and Pain 28
9. Neuropsychiatrie Symptoms 29
10. Cognitive Impairment 31
11. Dementia 33
12. Psychosis 35
13. Conclusions and Further Outlook 36
Acknowledgments 38
References 38
V
vi
Contents
3* Nonmotor Symptoms in Experimental Models
of Parkinson s Disease 63
Nataliya Titova, Anthony H,V. Schapira, K Ray Chaudhuri,
Mubasher A. Qamar, Elena Katunina, and Peter Jenner
1. Introduction 64
2. Experimental Models of PD and the Occurrence of Nonmotor
Symptoms 65
3. Relating NMS in Experimental Models of PD to Pathophysiology 68
4. Conclusions and Observations 81
References 82
4· The Epidemiology of Nonmotor Symptoms in
Parkinson s Disease (Cohort and Other Studies) 91
Elena Katunina and Nataliya Titova
1. Background: The Concept of Holistic Nonmotor Symptoms
in Parkinson s Disease and Difficulties With Data Capture 92
2. Comprehensive Clinical Assessment of NMS in PD 93
3. Holistic Assessment of Prevalence of NMS in PD 94
4. NMS Prevalence in Treated PD Cohorts 102
5» Studies With NMSS in PD 105
6. Age, Age of Onset, Disease Duration, and Prevalence of NMS in PD 105
7. Conclusions 107
References 108
5. Genes and Nonmotor Symptoms in Parkinson s Disease in
Ee-Wei Lim and Eng-King Tan
1. Introduction 112
2. Genetic Links to Individual NMS in PD 112
3. Conclusions 120
Acknowledgments 121
References 121
Further Reading 127
6. Nonmotor Signs in Genetic Forms of Parkinson s Disease 129
Meike Kasten, Connie Marras, and Christine Klein
1. Introduction 130
2. Definition of (Genetic) PD 131
3. Classification and Nomenclature of Monogenic Parkinson s Disease 132
4. Overview of Monogenic PD 132
Contents
vii
5. Literature Review on NMS in Genetic Parkinsonism 136
6. Methods and Limitations of Studies Reporting NMS in Patients
With Monogenic Parkinsonism 136
7. Missing Data 138
8. Frequency of Nonmotor Signs by Gene 139
9. Conclusions and Perspectives 152
Acknowledgments 153
References 154
Further Reading 156
7. Imaging the Nonmotor Symptoms in Parkinson s Disease 179
Tayyabah Yousaf, Heather Wilson, and Marios Politis
1. introduction 180
2. Cognition and Dementia 187
3. Perceptual Disorders 196
4. Depression 203
5. Apathy 207
6. Anxiety 209
7. Fatigue 210
8. Sleep 212
9. Rapid Eye Movement Sleep Behavior Disorder 212
10. Excessive Daytime Sleepiness 216
11. Restless Leg Syndrome 218
12. Olfactory Function/Hyposmia 224
13. Body Mass Index Changes 226
14. impulse Control Disorders 231
15. Conclusion 234
References 235
8. Biomarkers of Nonmotor Symptoms in Parkinson s Disease 259
Takuya Konno, Rana Hanna AL-Shaikh, Angela B. Deutschlander,
and Ryan J. Uitti
1. Introduction 260
2. Neuropsychiatrie Symptoms 261
3. Sleep Disorders 270
4. Autonomic Symptoms 273
5. Sensory Symptoms 274
6. Conclusion 275
References 276
viii
Contents
9, Measurement of Nonmotor Symptoms in Clinical Practice 291
Pablo Martinez-Martin, Carmen Rodriguez-Blazquez, Marla Joâo Forjaz,
Monica M. Kurtis, and Matej Skorvanek
1. Introduction 292
2. Rater-Based and Patient-Based Assessments 295
3. Testing Rating Scales and Questionnaires 297
4. Scales and Questionnaires for Assessment of Cognition and
Neuropsychiatrie Symptoms 300
5. Scales and Questionnaires for Assessment of Sleep Disorders 314
6. Scales and Questionnaires for Assessment of Pain 318
7. Scales and Questionnaires for Assessment of Dysautonomia 322
8. Scales and Questionnaires for Assessment of Fluctuations 328
9. Conclusions 332
References 334
10· Objective Measurement and Monitoring of Nonmotor
Symptoms in Parkinson s Disease 347
Lisa Klingelhoefer, Onanong Jltkritsadakul, and Roongroj Bhidayasiri
1. Introduction 348
2. Objective Assessments by NMSQuest Domains 349
3. Nonmotor Fluctuations 373
4. Conclusion 373
Acknowledgments 374
References 374
11. Nonmotor Symptoms and Natural History of Parkinson s
Disease: Evidence From Cognitive Dysfunction and Role
of Noninvasive Interventions 389
Roberta Biundo, Eleonora Fiorenzato, and Angelo Antonini
1. Introduction 390
2, Role of Nonpharmacological Interventions 395
3. Telemedicine: The Future of Rehabilitation? 401
4, Discussion 402
References 403
Further Reading 411
12. Nonmotor Symptoms in Parkinson s Disease: Gender
and Ethnic Differences 417
Anna Sauerbier, Abhishek Lenka, Azman Aris, and Pramod Kumar Pal
1. Introduction 418
2. Gender Differences in NMS 418
Contents
ix
3. Ethnic Differences in NMS 421
4. Factors That Might Explain the Impact of Gender and Ethnicity 437
5. Conclusion 440
References 441
Further Reading 446
13· Nonmotor Subtyping in Parkinson s Disease 447
Anna Sauerbier, Miguel Rosa-Grllo, Mubasher A. Qamar,
and K Ray Chaudhuri
1. Introduction 447
2. Studies Identifying Subgroups Within Parkinson s Disease 450
3. The implications of Non motor Subtypes in PD 469
References 471
14. Caregiver Burden and the Nonmotor Symptoms of
Parkinson s Disease 479
Jon P. Hiseman and Robin Fackrell
1. Caregiver Burden 483
2. Quantifying Carer Strain With Scales 483
3. Urinary Dysfunction 492
4. Sexual Dysfunction 493
References 495
15. Quality of Life and Nonmotor Symptoms in Parkinson s Disease 499
Paolo Barone, Roberto Erro, and Marina Picillo
1. Introduction 500
2. How to Measure HRQoL in PD 501
3. Holistic Nonmotor Studies and HRQoL 503
4. Specific NMS and HRQoL 504
5. Interventional Studies Targeting NMS and Impact on HRQoL 509
6. Conclusions 510
References 511
Further Reading 516
Section 2A
Specific Nonmotor Symptoms in Parkinson s Disease, Part 1
16. Nonmotor Aspects of Parkinson s Disease—How Do They Help
Diagnosis? 519
Ronald B. Postuma
1. Introduction 520
2. How to Evaluate Nonmotor Markers in Diagnosis 520
X
Contents
3. Nonmotor Markers in Clinical PD Diagnosis—Movement Disorder
Society Criteria 521
4. Nonmotor Tests as Supportive Criteria 522
5. Other Nonmotor Features 526
6. Final Consideration in Clinical PD—The Nonmotor Profile and
Pattern Recognition 529
7. Nonmotor Markers and Prodromal Diagnosis 530
8. Olfactory Loss 533
9. Autonomic Dysfunction 533
10. Anxiety and Depression 534
11. RBD 535
12. Conclusions 536
References 537
17, Anosmia and Ageusia in Parkinson s Disease 541
Arjun Tarakad and Joseph Jankovic
1. Introduction 542
2. Mechanisms of Olfaction and Gustation 542
3. Pathology 544
4. Testing Anosmia and Ageusia 545
5. Prevalence and Course of Anosmia and Ageusia in PD 547
6. Associated Features 548
7. Olfactory and Gustatory Dysfunction in Other Conditions 549
8. Treatment 550
9. Conclusion 551
References 551
18. Cognition in Parkinson s Disease 557
Claire O Callaghan and Simon J.G. Lewis
1. Introduction 558
2. Cognitive Impairment in Parkinson s Disease vs Parkinson s
Disease Dementia 559
3. Cognitive Impairment in Parkinson s Disease 560
4. Parkinson s Disease Dementia 567
5. Clinical Characteristics Associated With Cognitive Decline in PD 569
6. Genetic Characteristics Associated With Cognitive Decline in PD 570
7. Therapeutics 572
8. Conclusion 572
Acknowledgments 573
References 573
Contents
XI
19. Psychosis in Parkinson s Disease 585
Dominic H. ffytche and Dag Aarsland
1. Introduction 586
2. Clinical Aspects 587
3. Biomarkers, Risk Factors, and Explanatory Models 592
4. Treatment 603
5. Current Controversies and Future Research Directions 608
6. Conclusions 611
Acknowledgments 612
References 612
20. Depression and Anxiety in Parkinson s Disease 623
Anette Schrag and Raquei N. Taddei
1. Definition and Diagnosis 624
2. Subtypes of Depression and Anxiety in PD 624
3. Epidemiology 625
4. Impact on Quality of Life 632
5. Scales for Depression and Anxiety 633
6. Biomarkers in Depression and Anxiety in PD 637
7. Management 641
8. Conclusions 643
References 643
21. Apathy in Parkinson s Disease 657
Javier Pagonabarraga and Jaime Kutisevsky
1. The Concept of Apathy 657
2. The Clinical Relevance and Scientific Interest of Defining Apathetic
Syndromes 659
3. Apathy in PD: Frequency and Distribution of Apathetic Syndromes 662
4. Diagnosis of Apathy in Clinical Practice: Scales and Diagnostic
Criteria for PD 667
5. Treatment of Apathy in PD 669
6. Conclusions 670
References 672
22. Impulse Control and Related Disorders in Parkinson s Disease 679
Daniel Weintraub and Daniel O. Claassen
1. Introduction 680
2. Epidemiology of ICDs and Related Behaviors in PD 682
xii
Contents
3. Association between ICDs and PD Treatments 683
4. Other Clinical and Demographic Correlates 686
5. Psychiatric Comorbidity 686
6. Role of Neurotransmitters and Brain Regions in fmpulsive-Compulsive
Behaviors 688
7. Why some PD Patients Develop ICDs in the Context of Treatment 690
8. Cognition in of PD Patients with ICDs 693
9. Neural Substrate of ICDs in PD 696
10. Assessment and Diagnosis 703
11. Management 704
12. Conclusions and Future Directions 706
References 707
23. Sleep Dysfunction in Parkinson s Disease 719
Cristian Falup-Pecurariu and $tefania Diaconu
1. Introduction 720
2. Epidemiology 720
3. Pathophysiology 721
4. Classification of Sleep Problems 723
5. Assessment 731
6. Management 732
7. Conclusions 735
References 735
Further Reading 742
24. Fatigue in Parkinson s Disease
Benzi M. Kluger
1. Introduction
2. Defining Fatigue
3. Clinical Care for Fatigue in PD
4. Clinical Fatigue Research in PD
5. Conclusion
References
743
744
745
750
754
760
760
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| spelling | Nonmotor Parkinson's: The hidden face the many hidden faces edited by K. Ray Chaudhuri, Nataliya Titova First edition Cambridge, MA Academic Press 2017 xxv, 768 Seiten Illustrationen txt rdacontent n rdamedia nc rdacarrier International review of neurobiology volume 133 Parkinson-Krankheit (DE-588)4044683-9 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Parkinson-Krankheit (DE-588)4044683-9 s DE-604 Chaudhuri, K. Ray edt Titova, Nataliya edt International review of neurobiology volume 133 (DE-604)BV002534817 133 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029919457&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Nonmotor Parkinson's: The hidden face the many hidden faces International review of neurobiology Parkinson-Krankheit (DE-588)4044683-9 gnd |
| subject_GND | (DE-588)4044683-9 (DE-588)4143413-4 |
| title | Nonmotor Parkinson's: The hidden face the many hidden faces |
| title_auth | Nonmotor Parkinson's: The hidden face the many hidden faces |
| title_exact_search | Nonmotor Parkinson's: The hidden face the many hidden faces |
| title_full | Nonmotor Parkinson's: The hidden face the many hidden faces edited by K. Ray Chaudhuri, Nataliya Titova |
| title_fullStr | Nonmotor Parkinson's: The hidden face the many hidden faces edited by K. Ray Chaudhuri, Nataliya Titova |
| title_full_unstemmed | Nonmotor Parkinson's: The hidden face the many hidden faces edited by K. Ray Chaudhuri, Nataliya Titova |
| title_short | Nonmotor Parkinson's: The hidden face |
| title_sort | nonmotor parkinson s the hidden face the many hidden faces |
| title_sub | the many hidden faces |
| topic | Parkinson-Krankheit (DE-588)4044683-9 gnd |
| topic_facet | Parkinson-Krankheit Aufsatzsammlung |
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