Nonmotor Parkinson's: The hidden face: management and the hidden face of related disorders
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Cambridge, MA
Academic Press
2017
|
| Ausgabe: | First edition |
| Schriftenreihe: | International review of neurobiology
volume 134 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | xxv Seiten, Seiten 771-1505 Illustrationen |
| ISBN: | 9780128126035 |
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Datensatz im Suchindex
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|---|---|
| adam_text | CONTENTS
Contributors xv
Prefaces by Günther Deuschi and Christopher G. Goetz xix
The Editors Words xxiii
Section 2B
Specific Nonmotor Symptoms
in Parkinson s Disease, Part 2
25. Autonomic Dysfunction in Parkinson s Disease: Cardiovascular
Symptoms, Thermoregulation, and Urogenital Symptoms 771
Wolfgang H. Jost
1. Introduction 772
2. Cardiovascular Symptoms 773
3. Thermoregulation Symptoms (Perspiration-Related Symptoms) 777
4. Urinary Symptoms 778
5. Conclusion 782
References 783
26. The Gut and Nonmotor Symptoms in Parkinson s Disease 787
Lisa Kiingeihoefer and Heinz Reichmann
1. introduction 788
2. Gl Symptoms in PD 789
3. The Gut as Part of the Pathological Process in PD 793
4. The Gut-Brain Connection 798
5. Conclusion 799
Acknowledgments 800
References 800
27. Constipation in Parkinson s Disease 811
Fabrizio Stocchi and Margherita Torti
1. Introduction 812
2. Constipation: A Prodromal Sign and a Risk Factor for PD 812
3. Microbiota and SJBO 813
4. Definition and Diagnostic Criteria 814
5. Epidemiology 814
VI
Contents
6. Pathophysiology 816
7. Diagnosis 817
8. Motor Fluctuations and Constipation 818
9. Treatment 819
10. Acute Emergency Admission 822
References 823
Further Reading 826
28. Understanding and Treating Pain Syndromes
in Parkinson s Disease 827
Marialuisa Gandolfì, Christian Geroin, Angelo Antonini, Nicola Smania,
and Michele Tinazzi
1. Background 828
2. Pain Pathophysiology in People With PD 830
3. Evaluation of Pain Syndromes in People With PD 836
4. Procedures for Treating Pain in People With PD 838
5. Pharmacological Therapy 838
6. Surgical Approaches 840
7. Rehabilitation 846
8. Conclusions 850
References 850
Further Reading 858
29. Sexual Dysfunctions in Parkinson s Disease: An Underrated
Problem in a Much Discussed Disorder 859
Kalyan B. Bhattacharyya and Miguel Rosa-Grilo
1. Parkinson s Disease and Hypersexuality 863
2. Neuro biology of HS in PD 866
3. Assessment and Investigation of SDs in Parkinson s Disease 867
4. Management of SDs in Parkinson s Disease 868
5. Concluding Remarks 870
References 870
30. Osteoporosis: A Hidden Nonmotor Face of Parkinson s Disease 877
Vinod Metta, Tamara C. Sanchez, and Chandrasekhara Padmakumar
1. Introduction 878
2. Diagnosis and Treatment 885
3. Conclusions 888
References 888
Further Reading 890
Contents
vìi
31· Weight in Parkinson s Disease: Phenotypical Significance 891
Jagdish C Sharma and Anna Lewis
1. Introduction 892
2. Body Weight Homeostasis and Changes in PD 893
3. Weight Measurement 895
4. Body Weight Status and Change in PD 896
5. Changes in Body Weight in PD 897
6. Weight Gain and Obesity in PD 897
7. Weight Loss in PD 900
8. Significance of Low Body Weight and Weight Loss in PD 907
9. Identifying Weight-Loser PD Patients—The Park-Olfaction-Weight
Phenotype? 910
10. Conclusions 911
11. Recommendations and Implications on Disease Management 912
References 912
Further Reading 919
32. Visual Dysfunction in Parkinson s Disease 921
Richard A. Armstrong
1. Introduction 922
2. Dopamine Pathways in Eye and Brain 923
3. Neuropathological Changes 925
4. Visual Dysfunction in PD 926
5. Discussion and Conclusions 935
References 939
33. Nonmotor Fluctuations in Parkinson s Disease 947
Christiana Franke and Alexander Storch
1. Epidemiology and Risk Factors of NMF 949
2. Clinical Presentation of NMF 950
3. NMF and QoL 957
4. Pathophysiology of NMF 958
5. Management of NMF 959
Acknowledgments 965
References 965
34. Acute Presentation of Nonmotor Symptoms
in Parkinson s Disease 973
Kimberly Kwei and Steven Frucht
1. Introduction 973
2. Neuroleptic Malignant Syndrome 974
Contents
viii
3. Serotonin Syndrome 977
4. Dopamine Agonist Withdrawal Syndrome 979
5. Dystonic Storm 980
6. Conclusion 983
References 983
Section 3
Therapeutics and Nonmotor Symptoms
in Parkinson s Disease
35. Nonmotor Effects of Conventional and Transdermal Dopaminergic
Therapies in Parkinson s Disease 989
Ryul Kim and Beomseok Jeon
1. Introduction 990
2. The Effect of Dopaminergic Therapies on NMS 991
3. The Unwanted Effect of Dopaminergic Therapies on NMS 1003
4. Conclusions 1007
Acknowledgments 1008
References 1008
36. Infusional Therapies, Continuous Dopaminergic Stimulation,
and Nonmotor Symptoms 1019
Ulrika Mundt-Petersen and Per Odin
1. Introduction 1020
2. Background: Subcutaneous Apomorphine Infusion 1020
3. Effects on Nonmotor PD Symptoms 1023
4. Background: Levodopa-Carbidopa Intestinal Gel 1028
5. LCIG: Effects on Nonmotor PD Symptoms 1032
6. Conclusions 1038
References 1039
37. Deep Brain Stimulation and Nonmotor Symptoms 1045
Elliot Hogg, Jeffrey Wertheimer, Sarah Graner, and Michele Tagliati
1. Introduction 1046
2. Nonmotor Outcomes of DBS 1047
3. Neurobehavioral Profiles and DBS 1049
4. Autonomic Dysfunction 1060
Contents
IX
5. Sleep Disorders 1067
6. Sensory Symptoms 1073
References 1077
Further Reading 1089
38. Noninvasive Brain Stimulation and Implications for Nonmotor
Symptoms in Parkinson s Disease 1091
Irena Rektorova and Ľubomíra Anderková
1. Methods 1093
2. Results 1094
3. Discussion 1104
Acknowledgment 1106
References 1106
39. Botulinum Toxin Therapy for Nonmotor Aspects
of Parkinson s Disease 1111
Jarosław Sławek and Mariusz Madaliński
1. Introduction 1112
2. BoNT for Drooling 1113
3. Botulinum Toxin for Neurogenic Bladder 1121
4. BoNT for G! Dysfunctions 1128
5. BoNT for Pain Related to PD 1135
6. Botulinum Toxin for Hyperhidrosis 1136
7. Botulinum Toxin for Other Indications in PD 1137
References 1137
40. Nutrition and Nonmotor Symptoms of Parkinson s Disease 1143
Laurie K. Mischley
1. Introduction 1144
2. Evidence for Nutritional Deficiencies in PD 1145
3. PD Increases Risk of Malnutrition 1147
4. Diet and Risk of PD Incidence 1147
5. An Intestinal Disease That Spreads to the Brain? 1148
6. Symptom-Specific Nutritional Considerations 1150
7. Drug-Nutrient interactions 1153
8. Assessment of Nutritional Status 1154
9. Conclusions 1155
References 1156
X
Contents
41. Complementary and Alternative Medicine and Exercise in
Nonmotor Symptoms of Parkinson s Disease 1163
Indu Subramanian
1. Part 1: Complementary and Alternative Medicine (CAM) in Nonmotor
Symptoms (NMS) of Parkinson Disease (PD) 1165
2. Part 2: Exercise on NMS in PD 1174
3. Part 3: Therapy: PT and OT Effects on NMS 1181
4. Conclusions 1182
References 1183
42. Speech, Voice, and Communication 1189
Julia A. Johnson
1. Introduction 1190
2. Classical Description 1190
3. Communication 1191
4. Language 1193
5. Subtypes 1194
6. Assessments 1195
7. Treatment 1198
8. Into the Future 1201
9. Conclusion 1202
References 1202
43. Swallowing Dysfunctions in Parkinson s Disease 1207
Janine A. Simons
1. Background of Swallowing Disabilities 1208
2. Clinical Implications of Dysphagia and Relevance for Quality of Life 1214
3. Dysphagia Assessment 1212
4. Dysphagia Treatment 1225
5. Summary and Referrals 1230
References 1231
44. Palliative Care and Nonmotor Symptoms
in Parkinson s Disease and Parkinsonism 1239
Nataliya Titova and K Ray Chaudhuri
1. introduction: What Is Palliative Care? 1240
2. Palliative Care in Parkinson s Disease 1241
Contents
XI
3. Natural History of PD and Palliative Care 1244
4. Key Strategies for Management 1244
5. New Initiatives 1248
6. Palliative Care in Parkinsonism: MSA and PSP 1251
7. Conclusions 1251
Acknowledgments 1253
References 1253
45. Personalized Medicine and Nonmotor Symptoms
in Parkinson s Disease 1257
Nataliya Titova and K Ray Chaudhuri
1. introduction (Correction 1) 1258
2. Genetics 1259
3. Pharmacogenetics 1263
4. Age and Personalized Medicine 1266
5. Comorbidities 1267
6. Lifestyle 1270
7. Body Weight 1271
8. Personality and Perception of Treatment 1271
9. Pharmacoeconomics 1273
10. Biomarker-Driven Nonmotor Subtype-Specific Treatment of PD and
Personalized Medicine 1273
11. Conclusions 1277
References 1278
Section 4
Nonmotor Symptoms in Parkinsonism and Related Disorders
46. Nonmotor Features in Atypical Parkinsonism 1285
Kailash P. Bhatia and Maria Stamelou
1. Introduction 1286
2. NMS in MSA 1286
3. NMS in PSP and CBD 1290
4. NMS and Quality of Life in AP 1293
5. Treatment of NMS in AP 1294
6. Conclusion 1296
References 1296
xii
Contents
47. Nonmotor Symptoms in Vascular and Other Secondary
Parkinsonism 1303
Oleg S. Levin, Achcha Sh. Chimagomedova, Natalia A. Skripkina,
Elena A. Lyashenko, and Olga V. Babkina
1. Vascular Parkinsonism 1304
2. Normal Pressure Hydrocephalus 1312
3. Toxin-Induced Parkinsonism 1317
4. Drug-Induced Parkinsonism 1323
5. Conclusion 1326
References 1327
Further Reading 1334
48. Nonmotor Symptoms in Dystonia 1335
Julie Ann Kristy L. Torres and Raymond L. Rosales
1. Introduction 1335
2. NMS in Dystonia-Plus Syndromes 1337
3« NMS in Early-Onset Dystonia 1348
4. NMS in Focal Dystonia 1349
5. Conclusion 1359
References 1361
49. Nonmotor Symptoms in Essential Tremor and Other
Tremor Disorders 1373
Alessandro F. Fois, Hugo M. Briceno, and Victor S.G Fung
1. Introduction 1374
2. Essential Tremor 1374
3. Dystonie Tremor 1382
4. Orthostatic Tremor 1386
5. Lesional Tremor: Thalamic, Cerebellar, and Brain Stem Lesions 1387
6. Conclusions 1390
References 1390
50. Nonmotor Symptoms in Huntington Disease 1397
Francisco Cardoso
1. Introduction 1397
2. Behavioral Disturbances 1400
3. Cognitive Dysfunction 1402
4. Management 1404
Contents xiii
5. Conclusions 1405
References 1406
51, Nonmotor Symptoms in Amyotrophic Lateral Sclerosis:
A Systematic Review 1409
Ton Fang, Felix Jozsa, and Ammar Ai-Chaiabi
1. Introduction 1410
2. Methods 1412
3. Results 1415
4. Discussion 1433
Acknowledgments 1435
References 1435
52, Nonmotor Manifestations of Wilson s Disease 1443
Samar Biswas, Neelanjana Paul, and Shyamal K. Das
1. NMSinWD 1446
2. Treatment of Psychiatric Manifestation in WD 1449
3. Imaging 1450
4. Discussion 1455
5. Conclusion 1456
References 1456
53, Tourette Syndrome and Chronic Tic Disorders:
The Clinical Spectrum Beyond Tics 1461
Davide Martino, Christos Ganos, and Tamara M. Pringsheim
1. introduction 1462
2. Sensory Aspects of Tic Disorders 1462
3. Behavioral Problems in Tic Disorders: Comorbid ADHD 1467
4. Behavioral Problems in Tic Disorders: Comorbid Obsessive-Compulsive
Symptoms and Obsessive-Compulsive Disorder 1472
5. Behavioral Disturbances in Tic Disorders: Comorbid Anxiety and
Depression 1475
6. 8ebavioral Disturbances in Tic Disorders: Comorbid Impulse Control
Disorders, Impulsive Behaviors, and Impulsive Tics 1477
7. Behavioral Disturbances in Tic Disorders: Comorbid Autistic Spectrum
Disorders 1480
8. Sleep Disorders 1481
9. Conclusions 1482
References 1482
Further Reading 1490
xiv
Contents
Section 5
Nonmotor Parkinson’s and Future Directions
54. Nonmotor Parkinson s and Future Directions 1493
Nataliya Titova and K Ray Chaudhuri
1. Introduction 1494
2. Animal Models 1495
3. Overcoming Barriers Toward the Understanding of NMS in PD 1496
4. Validation of the Nonmotor Subtypes of PD
(Using Multimodal Biomarkers) 1498
5. Better Evidence Base for Treatment of Specific NMS in PD 1500
6. Make NMS Assessment (Including Burden Grading) an Obligatory
Assessment in the Clinic 1501
7. Personalized Medicine 1502
8. Exploration of the Role of Exercise and Complementary Medicine in the
Management of NMS in PD 1502
9* Conclusions 1504
References 1504
INTERNATIONAL REVIEW OF
EUROBIOLOCY
Nonmotor Parkinson s: The Hidden Face
Management and the Hidden Face of Related Disorders
Volume 154
Nonmotor symptoms of Parkinson s disease are integral to the
condition and are present from the prodromal to the palliative
stage. Described by James Parkinson 200 years back, the
nonmotor symptoms of Parkinson s disease have remained
underexplored and underrecognized even though they play a
major role in the quality of life of patients and caregivers. The book
cover is an illustration made by the Ukrainian artist Oleg Shupliak
known for illusory or camouflage painting. The cover hides the
face of the famous Dutch painter Van Gogh and exemplifies how
nonmotor symptoms, a hidden face of Parkinson s disease, could
be the real driver of the manifest symptoms. In addition, the book
also addresses little known aspects of nonmotor symptoms in
parkinsonian disorders and related conditions in two volumes.
Over 40 famous key opinion leaders have contributed to these
two volumes which is likely to be the defining resource on
nonmotor aspects of Parkinson s disease and related disorders
for many years to come. The book also reflects a global reach
addressing the ubiquitous presence of nonmotor symptoms in
Parkinson s disease and parkinsonism and attempts to highlight
the growing need for recognition and management of these
symptoms, currently an unmet need.
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| spelling | Nonmotor Parkinson's: The hidden face management and the hidden face of related disorders edited by K. Ray Chaudhuri, Nataliya Titova First edition Cambridge, MA Academic Press 2017 xxv Seiten, Seiten 771-1505 Illustrationen txt rdacontent n rdamedia nc rdacarrier International review of neurobiology volume 134 Parkinson-Krankheit (DE-588)4044683-9 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Parkinson-Krankheit (DE-588)4044683-9 s DE-604 Chaudhuri, K. Ray edt Titova, Nataliya edt International review of neurobiology volume 134 (DE-604)BV002534817 134 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029916880&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029916880&sequence=000002&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Nonmotor Parkinson's: The hidden face management and the hidden face of related disorders International review of neurobiology Parkinson-Krankheit (DE-588)4044683-9 gnd |
| subject_GND | (DE-588)4044683-9 (DE-588)4143413-4 |
| title | Nonmotor Parkinson's: The hidden face management and the hidden face of related disorders |
| title_auth | Nonmotor Parkinson's: The hidden face management and the hidden face of related disorders |
| title_exact_search | Nonmotor Parkinson's: The hidden face management and the hidden face of related disorders |
| title_full | Nonmotor Parkinson's: The hidden face management and the hidden face of related disorders edited by K. Ray Chaudhuri, Nataliya Titova |
| title_fullStr | Nonmotor Parkinson's: The hidden face management and the hidden face of related disorders edited by K. Ray Chaudhuri, Nataliya Titova |
| title_full_unstemmed | Nonmotor Parkinson's: The hidden face management and the hidden face of related disorders edited by K. Ray Chaudhuri, Nataliya Titova |
| title_short | Nonmotor Parkinson's: The hidden face |
| title_sort | nonmotor parkinson s the hidden face management and the hidden face of related disorders |
| title_sub | management and the hidden face of related disorders |
| topic | Parkinson-Krankheit (DE-588)4044683-9 gnd |
| topic_facet | Parkinson-Krankheit Aufsatzsammlung |
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| volume_link | (DE-604)BV002534817 |
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