Structure Activity Relationships of Monomeric and Dimeric Strychnine Analogs as Ligands Targeting Glycine Receptors: = Strukturaktivitätsbeziehungen von monomeren und dimeren Strychninanaloga als Liganden, die Glycinrezeptoren
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Abschlussarbeit Buch |
| Sprache: | English |
| Veröffentlicht: |
Würzburg
2016
|
| Schlagworte: | |
| Online-Zugang: | kostenfrei http://d-nb.info/1136864601/34 Inhaltsverzeichnis |
| Beschreibung: | veröffentlicht 2017 |
| Beschreibung: | VIII, 165 Seiten Illustrationen |
| Format: | Langzeitarchivierung gewährleistet, LZA |
Internformat
MARC
| LEADER | 00000nam a2200000zc 4500 | ||
|---|---|---|---|
| 001 | BV044461397 | ||
| 003 | DE-604 | ||
| 005 | 20170920 | ||
| 007 | t | ||
| 008 | 170825s2016 gw a||| m||| 00||| eng d | ||
| 015 | |a 17,O08 |2 dnb | ||
| 016 | 7 | |a 1136864601 |2 DE-101 | |
| 035 | |a (OCoLC)1159318962 | ||
| 035 | |a (DE-599)DNB1136864601 | ||
| 040 | |a DE-604 |b ger |e rda | ||
| 041 | 0 | |a eng | |
| 044 | |a gw |c XA-DE-BY | ||
| 049 | |a DE-384 |a DE-473 |a DE-703 |a DE-1051 |a DE-824 |a DE-29 |a DE-12 |a DE-91 |a DE-19 |a DE-1049 |a DE-92 |a DE-739 |a DE-898 |a DE-355 |a DE-706 |a DE-20 |a DE-1102 |a DE-860 |a DE-2174 | ||
| 082 | 0 | |a 610 |2 23 | |
| 084 | |a VS 5070 |0 (DE-625)159664: |2 rvk | ||
| 084 | |a 610 |2 sdnb | ||
| 100 | 1 | |a Mohsen, Amal Mahmoud Yassin |d ca. 21. Jh. |e Verfasser |0 (DE-588)1138844047 |4 aut | |
| 245 | 1 | 0 | |a Structure Activity Relationships of Monomeric and Dimeric Strychnine Analogs as Ligands Targeting Glycine Receptors |b = Strukturaktivitätsbeziehungen von monomeren und dimeren Strychninanaloga als Liganden, die Glycinrezeptoren |c vorgelegt von Amal Mahmoud Yassin Mohsen aus Kuwait |
| 246 | 1 | 1 | |a Strukturaktivitätsbeziehungen von monomeren und dimeren Strychninanaloga als Liganden, die Glycinrezeptoren |
| 264 | 1 | |a Würzburg |c 2016 | |
| 300 | |a VIII, 165 Seiten |b Illustrationen | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 500 | |a veröffentlicht 2017 | ||
| 502 | |b Dissertation |c Julius-Maximilians-Universität Würzburg |d 2016 | ||
| 538 | |a Langzeitarchivierung gewährleistet, LZA | ||
| 546 | |a Zusammenfassung in deutscher und englischer Sprache | ||
| 650 | 0 | 7 | |a Strychnin |0 (DE-588)4183814-2 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Monomere |0 (DE-588)4170473-3 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Dimere |0 (DE-588)4149937-2 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Ligand |g Biochemie |0 (DE-588)4606532-5 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Glycinrezeptor |0 (DE-588)4297843-9 |2 gnd |9 rswk-swf |
| 653 | |a strychnine | ||
| 655 | 7 | |0 (DE-588)4113937-9 |a Hochschulschrift |2 gnd-content | |
| 689 | 0 | 0 | |a Strychnin |0 (DE-588)4183814-2 |D s |
| 689 | 0 | 1 | |a Monomere |0 (DE-588)4170473-3 |D s |
| 689 | 0 | 2 | |a Dimere |0 (DE-588)4149937-2 |D s |
| 689 | 0 | 3 | |a Ligand |g Biochemie |0 (DE-588)4606532-5 |D s |
| 689 | 0 | 4 | |a Glycinrezeptor |0 (DE-588)4297843-9 |D s |
| 689 | 0 | |5 DE-604 | |
| 776 | 0 | 8 | |i Erscheint auch als |n Online-Ausgabe, PDF |o urn:nbn:de:bvb:20-opus-142228 |
| 856 | 4 | 1 | |u https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-142228 |x Resolving-System |z kostenfrei |3 Volltext |
| 856 | 4 | 1 | |u http://d-nb.info/1136864601/34 |x Langzeitarchivierung Nationalbibliothek |
| 856 | 4 | 2 | |m DNB Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029862058&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 912 | |a ebook | ||
| 999 | |a oai:aleph.bib-bvb.de:BVB01-029862058 | ||
Datensatz im Suchindex
| _version_ | 1804177785135038464 |
|---|---|
| adam_text | TABLE OF CONTENTS
ACKNOWLEDGMENTS.............................................................................I
TABLE OF CONTENTS
.....
.
.................................................................................
IV
LIST OF
FIGURES............................................................................................
VII
LIST OF
ABBREVIATIONS......................................................................................I
1.
INTRODUCTION...........................................................................................
3
1.1. LIGAND-GATED ION
CHANNELS.......................................................... 3
1.2. GLYCINE RECEPTORS AS LIGAND-GATED ION CHANNEL
.......................
4
1.2.1. GLYCINE RECEPTORS PHYSIOLOGICAL FUNCTIONS AND DISTRIBUTION
....
4
1.2.2. GLYCINE RECEPTORS
STRUCTURE...........................................................4
1.2.3. GLYCINE RECEPTOR
SUBTYPES............................................................. 5
1.2.4. GLYCINE BINDING
SITE........................................................................6
1.2.5. GLYCINE RECEPTORS GATING
................................................................
7
1.2.6. GLYCINE RECEPTORS
LIGANDS.............................................................. 9
1.3. STRYCHNINE
.....................................................................................
12
1.3.1. STRYCHNINE ORIGIN, PHYSICAL PROPERTIES AND DISCOVERY
..............
12
1.3.2. STRYCHNINE PHARMACOKINETIC
PROPERTIES........................................13
1.3.3. STRYCHNINE PHARMACOLOGICAL ACTIONS
............................................
13
1.4. CRYSTAL STRUCTURE OF THE HUMAN GLYCINE RECEPTOR BINDING TO
STRYCHNINE.................................................................................................15
1.5. STRUCTURE ACTIVITY RELATIONSHIP OF
STRYCHNINE...........................17
1.5.1. STRYCHNINE ANALOGS WITH ANTICONVULSIVE AND MUSCLE RELAXANT
EFFECTS.............................................................................................................
17
1.5.2. STRUCTURE ACTIVITY RELATIONSHIPS OF STRYCHNINE ANALOGS HAVING
ACTIVITY AT THE
GLYRS....................................................................................19
1.6. STRYCHNINE TOXICITY AND DETOXIFICATION
......................................
21
1.7. STRYCHNINE*S USES
22
1.8. BIVALENT LIGAND
APPROACH...........................................................23
1.8.1. BIVALENT LIGANDS BENEFITS
..............................................................
24
1.8.2. SOME EXAMPLES O F BIVALENT
LIGANDS............................................25
1.8.3. DESIGNING BIVALENT
LIGANDS..........................................................26
1.9. BIVALENT LIGANDS FOR ION
CHANNELS..............................................29
1.9.1. NICOTINIC ACETYLCHOLINE RECEPTOR (NACHR)
................................
29
1.9.2.
5
HT
3
SEROTONIN RECEPTORS
.............................................................
30
1.9.3. GABA
A
RECEPTORS..........................................................................
31
1.9.4. GLYCINE RECEPTOR DIMERIC LIGANDS
..............................................
33
2. AIM OF
WORK..........................................................................................35
3.
REFERENCES.............................................................................................38
4.
RESULTS...................................................................................................46
4.1. STRUCTURE-ACTIVITY RELATIONSHIPS OF STRYCHNINE ANALOGS AT
GLYCINE RECEPTORS
....................................................................................
46
4.2. OXIME ETHERS OF (E)-L 1-ISONITROSOSTRYCHNINE AS HIGHLY POTENT
GLYCINE RECEPTOR ANTAGONISTS
................................................................
59
4.3. DIMERIC STRYCHNINE ANALOGS AS BIVALENT LIGANDS TARGETING
GLYCINE RECEPTORS
....................................................................................
91
5. OVERALL DISCUSSION AND
CONCLUSION..................................................112
6. REFERENCES
..........................................................................................
118
7.
SUMMARY............................................................................................
119
8. ZUSAMMENFASSUNG
.............................................................................
122
9.
APPENDIX........................................................................................
126
9.1. NMR SPECTRA OF THE COMPOUNDS DESCRIBED IN CHAPTER 4.1 ...127
9.2. NMR SPECTRA OF THE COMPOUNDS DESCRIBED IN CHAPTER 4.2 ...137
9.3. NMR SPECTRA OF THE COMPOUNDS DESCRIBED IN CHAPTER 4.3 ...153
9.4. LC-MS CHROMATOGRAMS OF THE COMPOUNDS DESCRIBED IN
CHAPTER
4.3.............................................................................................
161
|
| any_adam_object | 1 |
| author | Mohsen, Amal Mahmoud Yassin ca. 21. Jh |
| author_GND | (DE-588)1138844047 |
| author_facet | Mohsen, Amal Mahmoud Yassin ca. 21. Jh |
| author_role | aut |
| author_sort | Mohsen, Amal Mahmoud Yassin ca. 21. Jh |
| author_variant | a m y m amy amym |
| building | Verbundindex |
| bvnumber | BV044461397 |
| classification_rvk | VS 5070 |
| collection | ebook |
| ctrlnum | (OCoLC)1159318962 (DE-599)DNB1136864601 |
| dewey-full | 610 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 610 - Medicine and health |
| dewey-raw | 610 |
| dewey-search | 610 |
| dewey-sort | 3610 |
| dewey-tens | 610 - Medicine and health |
| discipline | Chemie / Pharmazie Medizin |
| format | Thesis Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02850nam a2200589zc 4500</leader><controlfield tag="001">BV044461397</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20170920 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">170825s2016 gw a||| m||| 00||| eng d</controlfield><datafield tag="015" ind1=" " ind2=" "><subfield code="a">17,O08</subfield><subfield code="2">dnb</subfield></datafield><datafield tag="016" ind1="7" ind2=" "><subfield code="a">1136864601</subfield><subfield code="2">DE-101</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1159318962</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DNB1136864601</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="044" ind1=" " ind2=" "><subfield code="a">gw</subfield><subfield code="c">XA-DE-BY</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-384</subfield><subfield code="a">DE-473</subfield><subfield code="a">DE-703</subfield><subfield code="a">DE-1051</subfield><subfield code="a">DE-824</subfield><subfield code="a">DE-29</subfield><subfield code="a">DE-12</subfield><subfield code="a">DE-91</subfield><subfield code="a">DE-19</subfield><subfield code="a">DE-1049</subfield><subfield code="a">DE-92</subfield><subfield code="a">DE-739</subfield><subfield code="a">DE-898</subfield><subfield code="a">DE-355</subfield><subfield code="a">DE-706</subfield><subfield code="a">DE-20</subfield><subfield code="a">DE-1102</subfield><subfield code="a">DE-860</subfield><subfield code="a">DE-2174</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">610</subfield><subfield code="2">23</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">VS 5070</subfield><subfield code="0">(DE-625)159664:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">610</subfield><subfield code="2">sdnb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Mohsen, Amal Mahmoud Yassin</subfield><subfield code="d">ca. 21. Jh.</subfield><subfield code="e">Verfasser</subfield><subfield code="0">(DE-588)1138844047</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Structure Activity Relationships of Monomeric and Dimeric Strychnine Analogs as Ligands Targeting Glycine Receptors</subfield><subfield code="b">= Strukturaktivitätsbeziehungen von monomeren und dimeren Strychninanaloga als Liganden, die Glycinrezeptoren</subfield><subfield code="c">vorgelegt von Amal Mahmoud Yassin Mohsen aus Kuwait</subfield></datafield><datafield tag="246" ind1="1" ind2="1"><subfield code="a">Strukturaktivitätsbeziehungen von monomeren und dimeren Strychninanaloga als Liganden, die Glycinrezeptoren</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Würzburg</subfield><subfield code="c">2016</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">VIII, 165 Seiten</subfield><subfield code="b">Illustrationen</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">veröffentlicht 2017</subfield></datafield><datafield tag="502" ind1=" " ind2=" "><subfield code="b">Dissertation</subfield><subfield code="c">Julius-Maximilians-Universität Würzburg</subfield><subfield code="d">2016</subfield></datafield><datafield tag="538" ind1=" " ind2=" "><subfield code="a">Langzeitarchivierung gewährleistet, LZA</subfield></datafield><datafield tag="546" ind1=" " ind2=" "><subfield code="a">Zusammenfassung in deutscher und englischer Sprache</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Strychnin</subfield><subfield code="0">(DE-588)4183814-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Monomere</subfield><subfield code="0">(DE-588)4170473-3</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Dimere</subfield><subfield code="0">(DE-588)4149937-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Ligand</subfield><subfield code="g">Biochemie</subfield><subfield code="0">(DE-588)4606532-5</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Glycinrezeptor</subfield><subfield code="0">(DE-588)4297843-9</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">strychnine</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="0">(DE-588)4113937-9</subfield><subfield code="a">Hochschulschrift</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Strychnin</subfield><subfield code="0">(DE-588)4183814-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Monomere</subfield><subfield code="0">(DE-588)4170473-3</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="2"><subfield code="a">Dimere</subfield><subfield code="0">(DE-588)4149937-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="3"><subfield code="a">Ligand</subfield><subfield code="g">Biochemie</subfield><subfield code="0">(DE-588)4606532-5</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="4"><subfield code="a">Glycinrezeptor</subfield><subfield code="0">(DE-588)4297843-9</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Online-Ausgabe, PDF</subfield><subfield code="o">urn:nbn:de:bvb:20-opus-142228</subfield></datafield><datafield tag="856" ind1="4" ind2="1"><subfield code="u">https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-142228</subfield><subfield code="x">Resolving-System</subfield><subfield code="z">kostenfrei</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="856" ind1="4" ind2="1"><subfield code="u">http://d-nb.info/1136864601/34</subfield><subfield code="x">Langzeitarchivierung Nationalbibliothek</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">DNB Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029862058&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ebook</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-029862058</subfield></datafield></record></collection> |
| genre | (DE-588)4113937-9 Hochschulschrift gnd-content |
| genre_facet | Hochschulschrift |
| id | DE-604.BV044461397 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T07:53:35Z |
| institution | BVB |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-029862058 |
| oclc_num | 1159318962 |
| open_access_boolean | 1 |
| owner | DE-384 DE-473 DE-BY-UBG DE-703 DE-1051 DE-824 DE-29 DE-12 DE-91 DE-BY-TUM DE-19 DE-BY-UBM DE-1049 DE-92 DE-739 DE-898 DE-BY-UBR DE-355 DE-BY-UBR DE-706 DE-20 DE-1102 DE-860 DE-2174 |
| owner_facet | DE-384 DE-473 DE-BY-UBG DE-703 DE-1051 DE-824 DE-29 DE-12 DE-91 DE-BY-TUM DE-19 DE-BY-UBM DE-1049 DE-92 DE-739 DE-898 DE-BY-UBR DE-355 DE-BY-UBR DE-706 DE-20 DE-1102 DE-860 DE-2174 |
| physical | VIII, 165 Seiten Illustrationen |
| psigel | ebook |
| publishDate | 2016 |
| publishDateSearch | 2016 |
| publishDateSort | 2016 |
| record_format | marc |
| spelling | Mohsen, Amal Mahmoud Yassin ca. 21. Jh. Verfasser (DE-588)1138844047 aut Structure Activity Relationships of Monomeric and Dimeric Strychnine Analogs as Ligands Targeting Glycine Receptors = Strukturaktivitätsbeziehungen von monomeren und dimeren Strychninanaloga als Liganden, die Glycinrezeptoren vorgelegt von Amal Mahmoud Yassin Mohsen aus Kuwait Strukturaktivitätsbeziehungen von monomeren und dimeren Strychninanaloga als Liganden, die Glycinrezeptoren Würzburg 2016 VIII, 165 Seiten Illustrationen txt rdacontent n rdamedia nc rdacarrier veröffentlicht 2017 Dissertation Julius-Maximilians-Universität Würzburg 2016 Langzeitarchivierung gewährleistet, LZA Zusammenfassung in deutscher und englischer Sprache Strychnin (DE-588)4183814-2 gnd rswk-swf Monomere (DE-588)4170473-3 gnd rswk-swf Dimere (DE-588)4149937-2 gnd rswk-swf Ligand Biochemie (DE-588)4606532-5 gnd rswk-swf Glycinrezeptor (DE-588)4297843-9 gnd rswk-swf strychnine (DE-588)4113937-9 Hochschulschrift gnd-content Strychnin (DE-588)4183814-2 s Monomere (DE-588)4170473-3 s Dimere (DE-588)4149937-2 s Ligand Biochemie (DE-588)4606532-5 s Glycinrezeptor (DE-588)4297843-9 s DE-604 Erscheint auch als Online-Ausgabe, PDF urn:nbn:de:bvb:20-opus-142228 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-142228 Resolving-System kostenfrei Volltext http://d-nb.info/1136864601/34 Langzeitarchivierung Nationalbibliothek DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029862058&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Mohsen, Amal Mahmoud Yassin ca. 21. Jh Structure Activity Relationships of Monomeric and Dimeric Strychnine Analogs as Ligands Targeting Glycine Receptors = Strukturaktivitätsbeziehungen von monomeren und dimeren Strychninanaloga als Liganden, die Glycinrezeptoren Strychnin (DE-588)4183814-2 gnd Monomere (DE-588)4170473-3 gnd Dimere (DE-588)4149937-2 gnd Ligand Biochemie (DE-588)4606532-5 gnd Glycinrezeptor (DE-588)4297843-9 gnd |
| subject_GND | (DE-588)4183814-2 (DE-588)4170473-3 (DE-588)4149937-2 (DE-588)4606532-5 (DE-588)4297843-9 (DE-588)4113937-9 |
| title | Structure Activity Relationships of Monomeric and Dimeric Strychnine Analogs as Ligands Targeting Glycine Receptors = Strukturaktivitätsbeziehungen von monomeren und dimeren Strychninanaloga als Liganden, die Glycinrezeptoren |
| title_alt | Strukturaktivitätsbeziehungen von monomeren und dimeren Strychninanaloga als Liganden, die Glycinrezeptoren |
| title_auth | Structure Activity Relationships of Monomeric and Dimeric Strychnine Analogs as Ligands Targeting Glycine Receptors = Strukturaktivitätsbeziehungen von monomeren und dimeren Strychninanaloga als Liganden, die Glycinrezeptoren |
| title_exact_search | Structure Activity Relationships of Monomeric and Dimeric Strychnine Analogs as Ligands Targeting Glycine Receptors = Strukturaktivitätsbeziehungen von monomeren und dimeren Strychninanaloga als Liganden, die Glycinrezeptoren |
| title_full | Structure Activity Relationships of Monomeric and Dimeric Strychnine Analogs as Ligands Targeting Glycine Receptors = Strukturaktivitätsbeziehungen von monomeren und dimeren Strychninanaloga als Liganden, die Glycinrezeptoren vorgelegt von Amal Mahmoud Yassin Mohsen aus Kuwait |
| title_fullStr | Structure Activity Relationships of Monomeric and Dimeric Strychnine Analogs as Ligands Targeting Glycine Receptors = Strukturaktivitätsbeziehungen von monomeren und dimeren Strychninanaloga als Liganden, die Glycinrezeptoren vorgelegt von Amal Mahmoud Yassin Mohsen aus Kuwait |
| title_full_unstemmed | Structure Activity Relationships of Monomeric and Dimeric Strychnine Analogs as Ligands Targeting Glycine Receptors = Strukturaktivitätsbeziehungen von monomeren und dimeren Strychninanaloga als Liganden, die Glycinrezeptoren vorgelegt von Amal Mahmoud Yassin Mohsen aus Kuwait |
| title_short | Structure Activity Relationships of Monomeric and Dimeric Strychnine Analogs as Ligands Targeting Glycine Receptors |
| title_sort | structure activity relationships of monomeric and dimeric strychnine analogs as ligands targeting glycine receptors strukturaktivitatsbeziehungen von monomeren und dimeren strychninanaloga als liganden die glycinrezeptoren |
| title_sub | = Strukturaktivitätsbeziehungen von monomeren und dimeren Strychninanaloga als Liganden, die Glycinrezeptoren |
| topic | Strychnin (DE-588)4183814-2 gnd Monomere (DE-588)4170473-3 gnd Dimere (DE-588)4149937-2 gnd Ligand Biochemie (DE-588)4606532-5 gnd Glycinrezeptor (DE-588)4297843-9 gnd |
| topic_facet | Strychnin Monomere Dimere Ligand Biochemie Glycinrezeptor Hochschulschrift |
| url | https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-142228 http://d-nb.info/1136864601/34 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029862058&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT mohsenamalmahmoudyassin structureactivityrelationshipsofmonomericanddimericstrychnineanalogsasligandstargetingglycinereceptorsstrukturaktivitatsbeziehungenvonmonomerenunddimerenstrychninanalogaalsligandendieglycinrezeptoren AT mohsenamalmahmoudyassin strukturaktivitatsbeziehungenvonmonomerenunddimerenstrychninanalogaalsligandendieglycinrezeptoren |