Advances in protein chemistry and structural biology, Protein structure and diseases:
Structural genomics is the systematic determination of 3-dimensional structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any prote...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Kidlington, Oxford, UK Waltham, MA
Academic Press/Elsevier
[2011]
|
| Ausgabe: | First edition |
| Schriftenreihe: | Advances in protein chemistry and structural biology
v. 83 |
| Schlagworte: | |
| Online-Zugang: | FAW01 Volltext |
| Zusammenfassung: | Structural genomics is the systematic determination of 3-dimensional structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome. While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large scale cloning, expression and purification. One main advantage of this approach is economy of scale. Key Features *Examines the three dimensional structure of all proteins of a given organism, by experimental methods such as X-ray crystallography and NMR spectroscopy * Looks at structural genomics as a foundation of drug discovery as discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission |
| Beschreibung: | Includes bibliographical references and indexes |
| Beschreibung: | 1 online resource (vii, 304 pages) illustrations (some color) |
| ISBN: | 9780123812636 0123812631 9780123812629 0123812623 |
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| 520 | |a Structural genomics is the systematic determination of 3-dimensional structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome. While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large scale cloning, expression and purification. One main advantage of this approach is economy of scale. Key Features *Examines the three dimensional structure of all proteins of a given organism, by experimental methods such as X-ray crystallography and NMR spectroscopy * Looks at structural genomics as a foundation of drug discovery as discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission | ||
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| illustrated | Illustrated |
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| isbn | 9780123812636 0123812631 9780123812629 0123812623 |
| language | English |
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| series2 | Advances in protein chemistry and structural biology |
| spelling | Advances in protein chemistry and structural biology, Protein structure and diseases edited by Rossen Donev Protein structure and diseases First edition Kidlington, Oxford, UK Waltham, MA Academic Press/Elsevier [2011] 1 online resource (vii, 304 pages) illustrations (some color) txt rdacontent c rdamedia cr rdacarrier Advances in protein chemistry and structural biology v. 83 Includes bibliographical references and indexes Structural genomics is the systematic determination of 3-dimensional structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome. While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large scale cloning, expression and purification. One main advantage of this approach is economy of scale. Key Features *Examines the three dimensional structure of all proteins of a given organism, by experimental methods such as X-ray crystallography and NMR spectroscopy * Looks at structural genomics as a foundation of drug discovery as discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission Protein Conformation Proteins / chemistry Disease SCIENCE / Life Sciences / Biochemistry bisacsh Proteins / Structure fast Proteins Structure Proteine (DE-588)4076388-2 gnd rswk-swf Strukturbiologie (DE-588)1081522143 gnd rswk-swf Proteine (DE-588)4076388-2 s Strukturbiologie (DE-588)1081522143 s DE-604 Donev, Rossen edt Protein structure and diseases Oxford : Academic, 2011 9780123812629 http://www.sciencedirect.com/science/bookseries/18761623/83 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Advances in protein chemistry and structural biology, Protein structure and diseases Protein Conformation Proteins / chemistry Disease SCIENCE / Life Sciences / Biochemistry bisacsh Proteins / Structure fast Proteins Structure Proteine (DE-588)4076388-2 gnd Strukturbiologie (DE-588)1081522143 gnd |
| subject_GND | (DE-588)4076388-2 (DE-588)1081522143 |
| title | Advances in protein chemistry and structural biology, Protein structure and diseases |
| title_alt | Protein structure and diseases |
| title_auth | Advances in protein chemistry and structural biology, Protein structure and diseases |
| title_exact_search | Advances in protein chemistry and structural biology, Protein structure and diseases |
| title_full | Advances in protein chemistry and structural biology, Protein structure and diseases edited by Rossen Donev |
| title_fullStr | Advances in protein chemistry and structural biology, Protein structure and diseases edited by Rossen Donev |
| title_full_unstemmed | Advances in protein chemistry and structural biology, Protein structure and diseases edited by Rossen Donev |
| title_short | Advances in protein chemistry and structural biology, Protein structure and diseases |
| title_sort | advances in protein chemistry and structural biology protein structure and diseases |
| topic | Protein Conformation Proteins / chemistry Disease SCIENCE / Life Sciences / Biochemistry bisacsh Proteins / Structure fast Proteins Structure Proteine (DE-588)4076388-2 gnd Strukturbiologie (DE-588)1081522143 gnd |
| topic_facet | Protein Conformation Proteins / chemistry Disease SCIENCE / Life Sciences / Biochemistry Proteins / Structure Proteins Structure Proteine Strukturbiologie |
| url | http://www.sciencedirect.com/science/bookseries/18761623/83 |
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