Protein folding in silico: protein folding versus protein structure prediction
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Philadelphia, Pa
Woodhead Pub.
2012
|
| Schriftenreihe: | Woodhead Publishing series in biomedicine
no. 22 |
| Schlagworte: | |
| Online-Zugang: | FAW01 Volltext |
| Beschreibung: | Includes bibliographical references and index Protein folding is a process by which a protein structure assumes its functional shape of conformation, and has been the subject of research since the publication of the first software tool for protein structure prediction. Protein folding in silico approaches this issue by introducing an ab initio model that attempts to simulate as far as possible the folding process as it takes place in vivo, and attempts to construct a mechanistic model on the basis of the predictions made. The opening chapters discuss the early stage intermediate and late stage intermediate models, followed by a discussion of structural information that affects the interpretation of the folding process. The second half of the book covers a variety of topics including ligand binding site recognition, the "fuzzy oil drop" model and its use in simulation of the polypeptide chain, and misfolded proteins. The book ends with an overview of a number of other ab initio methods for protein structure predictions and some concluding remarks. Discusses a range of ab initio models for protein structure predictionIntroduces a unique model based on experimental observationsDescribes various methods for the quantitative assessment of the presented models from the viewpoint of information theory |
| Beschreibung: | xxxii, 208 pages |
| ISBN: | 9781908818256 1908818255 9781907568176 |
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| 264 | 1 | |a Philadelphia, Pa |b Woodhead Pub. |c 2012 | |
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| 490 | 0 | |a Woodhead Publishing series in biomedicine |v no. 22 | |
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| 500 | |a Protein folding is a process by which a protein structure assumes its functional shape of conformation, and has been the subject of research since the publication of the first software tool for protein structure prediction. Protein folding in silico approaches this issue by introducing an ab initio model that attempts to simulate as far as possible the folding process as it takes place in vivo, and attempts to construct a mechanistic model on the basis of the predictions made. The opening chapters discuss the early stage intermediate and late stage intermediate models, followed by a discussion of structural information that affects the interpretation of the folding process. The second half of the book covers a variety of topics including ligand binding site recognition, the "fuzzy oil drop" model and its use in simulation of the polypeptide chain, and misfolded proteins. The book ends with an overview of a number of other ab initio methods for protein structure predictions and some concluding remarks. Discusses a range of ab initio models for protein structure predictionIntroduces a unique model based on experimental observationsDescribes various methods for the quantitative assessment of the presented models from the viewpoint of information theory | ||
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| spelling | Protein folding in silico protein folding versus protein structure prediction edited by Irena Roterman-Konieczna Philadelphia, Pa Woodhead Pub. 2012 xxxii, 208 pages txt rdacontent c rdamedia cr rdacarrier Woodhead Publishing series in biomedicine no. 22 Includes bibliographical references and index Protein folding is a process by which a protein structure assumes its functional shape of conformation, and has been the subject of research since the publication of the first software tool for protein structure prediction. Protein folding in silico approaches this issue by introducing an ab initio model that attempts to simulate as far as possible the folding process as it takes place in vivo, and attempts to construct a mechanistic model on the basis of the predictions made. The opening chapters discuss the early stage intermediate and late stage intermediate models, followed by a discussion of structural information that affects the interpretation of the folding process. The second half of the book covers a variety of topics including ligand binding site recognition, the "fuzzy oil drop" model and its use in simulation of the polypeptide chain, and misfolded proteins. The book ends with an overview of a number of other ab initio methods for protein structure predictions and some concluding remarks. Discusses a range of ab initio models for protein structure predictionIntroduces a unique model based on experimental observationsDescribes various methods for the quantitative assessment of the presented models from the viewpoint of information theory SCIENCE / Life Sciences / Biochemistry bisacsh Protein folding fast Proteins / Structure / Computer simulation fast Computer simulation Models, Theoretical Protein folding / Simulation methods Protein folding Proteins Structure Computer simulation Proteinfaltung (DE-588)4324567-5 gnd rswk-swf In silico-Methode (DE-588)4816890-7 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Proteinfaltung (DE-588)4324567-5 s In silico-Methode (DE-588)4816890-7 s 2\p DE-604 Roterman-Konieczna, Irena Sonstige oth http://www.sciencedirect.com/science/book/9781907568176 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Protein folding in silico protein folding versus protein structure prediction SCIENCE / Life Sciences / Biochemistry bisacsh Protein folding fast Proteins / Structure / Computer simulation fast Computer simulation Models, Theoretical Protein folding / Simulation methods Protein folding Proteins Structure Computer simulation Proteinfaltung (DE-588)4324567-5 gnd In silico-Methode (DE-588)4816890-7 gnd |
| subject_GND | (DE-588)4324567-5 (DE-588)4816890-7 (DE-588)4143413-4 |
| title | Protein folding in silico protein folding versus protein structure prediction |
| title_auth | Protein folding in silico protein folding versus protein structure prediction |
| title_exact_search | Protein folding in silico protein folding versus protein structure prediction |
| title_full | Protein folding in silico protein folding versus protein structure prediction edited by Irena Roterman-Konieczna |
| title_fullStr | Protein folding in silico protein folding versus protein structure prediction edited by Irena Roterman-Konieczna |
| title_full_unstemmed | Protein folding in silico protein folding versus protein structure prediction edited by Irena Roterman-Konieczna |
| title_short | Protein folding in silico |
| title_sort | protein folding in silico protein folding versus protein structure prediction |
| title_sub | protein folding versus protein structure prediction |
| topic | SCIENCE / Life Sciences / Biochemistry bisacsh Protein folding fast Proteins / Structure / Computer simulation fast Computer simulation Models, Theoretical Protein folding / Simulation methods Protein folding Proteins Structure Computer simulation Proteinfaltung (DE-588)4324567-5 gnd In silico-Methode (DE-588)4816890-7 gnd |
| topic_facet | SCIENCE / Life Sciences / Biochemistry Protein folding Proteins / Structure / Computer simulation Computer simulation Models, Theoretical Protein folding / Simulation methods Proteins Structure Computer simulation Proteinfaltung In silico-Methode Aufsatzsammlung |
| url | http://www.sciencedirect.com/science/book/9781907568176 |
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