Recent advances in electron cryomicroscopy, Part A:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam
Academic Press/Elsevier
©2010
|
| Schriftenreihe: | Advances in protein chemistry and structural biology
v. 81 |
| Schlagworte: | |
| Online-Zugang: | FAW01 Volltext |
| Beschreibung: | Includes bibliographical references and index Structural genomics is the systematic determination of 3-dimensional structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome. While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large scale cloning, expression and purification. One main advantage of this approach is economy of scale. Key Features *Examines the three dimensional structure of all proteins of a given organism, by experimental methods such as X-ray crystallography and NMR spectroscopy * Looks at structural genomics as a foundation of drug discovery as discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission |
| Beschreibung: | vi, 132 pages |
| ISBN: | 9780123813589 0123813581 9780123813572 0123813573 128295489X 9781282954892 |
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| isbn | 9780123813589 0123813581 9780123813572 0123813573 128295489X 9781282954892 |
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| series2 | Advances in protein chemistry and structural biology |
| spelling | Recent advances in electron cryomicroscopy, Part A edited by Steven J. Ludtke and B.V. Venkataram Prasad Amsterdam Academic Press/Elsevier ©2010 vi, 132 pages txt rdacontent c rdamedia cr rdacarrier Advances in protein chemistry and structural biology v. 81 Includes bibliographical references and index Structural genomics is the systematic determination of 3-dimensional structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome. While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large scale cloning, expression and purification. One main advantage of this approach is economy of scale. Key Features *Examines the three dimensional structure of all proteins of a given organism, by experimental methods such as X-ray crystallography and NMR spectroscopy * Looks at structural genomics as a foundation of drug discovery as discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission SCIENCE / Electron Microscopes & Microscopy bisacsh Biochemistry fast Cryomicroscopy fast Electron microscopy fast Proteins / Structure fast Cryomicroscopy Electron microscopy Proteins Structure Biochemistry Methods Ludtke, Steven J. Sonstige oth Venkataram Prasad, B. V. Sonstige oth http://www.sciencedirect.com/science/bookseries/18761623/81 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Recent advances in electron cryomicroscopy, Part A SCIENCE / Electron Microscopes & Microscopy bisacsh Biochemistry fast Cryomicroscopy fast Electron microscopy fast Proteins / Structure fast Cryomicroscopy Electron microscopy Proteins Structure Biochemistry Methods |
| title | Recent advances in electron cryomicroscopy, Part A |
| title_auth | Recent advances in electron cryomicroscopy, Part A |
| title_exact_search | Recent advances in electron cryomicroscopy, Part A |
| title_full | Recent advances in electron cryomicroscopy, Part A edited by Steven J. Ludtke and B.V. Venkataram Prasad |
| title_fullStr | Recent advances in electron cryomicroscopy, Part A edited by Steven J. Ludtke and B.V. Venkataram Prasad |
| title_full_unstemmed | Recent advances in electron cryomicroscopy, Part A edited by Steven J. Ludtke and B.V. Venkataram Prasad |
| title_short | Recent advances in electron cryomicroscopy, Part A |
| title_sort | recent advances in electron cryomicroscopy part a |
| topic | SCIENCE / Electron Microscopes & Microscopy bisacsh Biochemistry fast Cryomicroscopy fast Electron microscopy fast Proteins / Structure fast Cryomicroscopy Electron microscopy Proteins Structure Biochemistry Methods |
| topic_facet | SCIENCE / Electron Microscopes & Microscopy Biochemistry Cryomicroscopy Electron microscopy Proteins / Structure Proteins Structure Biochemistry Methods |
| url | http://www.sciencedirect.com/science/bookseries/18761623/81 |
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