Progress in medicinal chemistry, Volume 46:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam
Elsevier
2008
|
| Schlagworte: | |
| Online-Zugang: | FAW01 Volltext |
| Beschreibung: | Includes bibliographical references and index Appropriate selection of biochemical targets is one of the most important drivers of cost effectiveness in the discovery of new medicines. Despite the many advances in genetics, genomics and systems biology, 'validation' of a target is not achieved until therapeutic efficacy is demonstrated by a drug candidate. Volume 46 of this series reviews the medicinal chemistry aimed at six diverse targets from which important new medicines are emerging: * HIV integrase (discovery of the first-in-class inhibitor drug raltegravir) * 11-beta-Hydroxysteroid dehydrogenase (new approach to glucocorticoid regulation) * Nicotinic a7 choline receptor (agonists and positive allosteric modulators). * Bradykinin receptor (new approach to pain therapy) * Histone deacetylase (new drugs for cancer) * 5-HT2c receptor modulators (various CNS indications) *Presents the latest research in the field of drug discovery *Publishes on an annual basis to bring you the most innovative updates in medicinal chemistry *Available as an online resource via ScienceDirect |
| Beschreibung: | 1 volume |
| ISBN: | 9780080569680 0080569684 0444530185 9780444530189 1281273066 9781281273062 |
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| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
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| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
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| spelling | Progress in medicinal chemistry, Volume 46 editors, G. Lawton and D.R. Witty Amsterdam Elsevier 2008 1 volume txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references and index Appropriate selection of biochemical targets is one of the most important drivers of cost effectiveness in the discovery of new medicines. Despite the many advances in genetics, genomics and systems biology, 'validation' of a target is not achieved until therapeutic efficacy is demonstrated by a drug candidate. Volume 46 of this series reviews the medicinal chemistry aimed at six diverse targets from which important new medicines are emerging: * HIV integrase (discovery of the first-in-class inhibitor drug raltegravir) * 11-beta-Hydroxysteroid dehydrogenase (new approach to glucocorticoid regulation) * Nicotinic a7 choline receptor (agonists and positive allosteric modulators). * Bradykinin receptor (new approach to pain therapy) * Histone deacetylase (new drugs for cancer) * 5-HT2c receptor modulators (various CNS indications) *Presents the latest research in the field of drug discovery *Publishes on an annual basis to bring you the most innovative updates in medicinal chemistry *Available as an online resource via ScienceDirect MEDICAL / Drug Guides bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh MEDICAL / Nursing / Pharmacology bisacsh Pharmaceutical chemistry fast Medizin Pharmaceutical chemistry Lawton, G. Sonstige oth Witty, D. R. Sonstige oth http://www.sciencedirect.com/science/bookseries/00796468/46 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Progress in medicinal chemistry, Volume 46 MEDICAL / Drug Guides bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh MEDICAL / Nursing / Pharmacology bisacsh Pharmaceutical chemistry fast Medizin Pharmaceutical chemistry |
| title | Progress in medicinal chemistry, Volume 46 |
| title_auth | Progress in medicinal chemistry, Volume 46 |
| title_exact_search | Progress in medicinal chemistry, Volume 46 |
| title_full | Progress in medicinal chemistry, Volume 46 editors, G. Lawton and D.R. Witty |
| title_fullStr | Progress in medicinal chemistry, Volume 46 editors, G. Lawton and D.R. Witty |
| title_full_unstemmed | Progress in medicinal chemistry, Volume 46 editors, G. Lawton and D.R. Witty |
| title_short | Progress in medicinal chemistry, Volume 46 |
| title_sort | progress in medicinal chemistry volume 46 |
| topic | MEDICAL / Drug Guides bisacsh MEDICAL / Pharmacology bisacsh MEDICAL / Pharmacy bisacsh MEDICAL / Nursing / Pharmacology bisacsh Pharmaceutical chemistry fast Medizin Pharmaceutical chemistry |
| topic_facet | MEDICAL / Drug Guides MEDICAL / Pharmacology MEDICAL / Pharmacy MEDICAL / Nursing / Pharmacology Pharmaceutical chemistry Medizin |
| url | http://www.sciencedirect.com/science/bookseries/00796468/46 |
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