Adenoviral vectors for gene therapy:
Gespeichert in:
Bibliographische Detailangaben
Weitere Verfasser: Curiel, David 19XX- (HerausgeberIn)
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: Amsterdam Academic Press © 2002
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Online-Zugang:FAW01
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Beschreibung:Adenoviral Vectors for Gene Therapy provides detailed and comprehensive coverage of these important therapeutic agents. The topics covered in this book range from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology and the use of adenoviral vectors in preclinical animal models, to regulatory issues which must be considered prior to the initiation of human clinical gene therapy trials. The broad scope of this unique volume provides the reader with a complete understanding of the development and use of adenoviral vectors. Key Features * Provides complete coverage of basic biology of adenoviruses, as well as the construction, propagation and purification of adenoviral vectors * Introduces common strategies for the development of adenoviral vectors along with cutting-edge methods for their improvement * Demonstrates noninvasive imaging of adenovirus-mediated gene transfer * Discusses utility of adenoviral vectors in animal disease models * Considers Federal Drug Administration regulations for human clinical trials
Includes bibliographical references
Beschreibung:xxviii, 677 pages
ISBN:9781435632004
1435632001
9780121995041
0121995046
128118652X
9781281186522

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