Complement regulatory proteins:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
San Diego
Academic Press
©1999
|
| Schlagworte: | |
| Online-Zugang: | FAW01 Volltext |
| Beschreibung: | From small beginnings in the early 1970s, the study of complement regulatory proteins has grown in the last decade to the point where it dominates the complement field. This growth has been fueled by the discovery of new regulators, the cloning of old and new regulators, the discovery that many of the regulators are structurally and evolutionarily related to each other and the development of recombinant forms for use in therapy. There are now more proteins known to be involved in controlling the complement system than there are components of the system and the list continues to grow. The time is ripe for a comprehensive review of our current knowledge of these intriguing proteins. This book does just that. The first few chapters discuss the "nuts-and-bolts" of the complement regulators, describing their structures, functional roles and modes of action. The roles of the complement regulators in vivo are then described, focusing on the consequences of deficiency, roles in the reproductive system, interactions with pathogens and exploitation for therapy. The interesting developments in defining the complement regulators expressed in other species are also discussed. The book is written as a monograph, albeit by two people. The text is as readable as possible without compromising on scientific accuracy and completeness. The conversational style very evident in some sections is deliberate! Placing all references in a single bibliography at the end of the text further improves readability. The reader will go to the book to discover a specific fact but be persuaded to read more and derive pleasure from the process. The authors' enthusiasm for the subject comes over strongly in the text, and this enthusiasm proves infectious. Key Features * Complement regulators--structure, functional roles and mode of action * Comprehensive reviews of each of the individual regulators * Roles of Complement regulators in vivo, in health and disease: * Consequences of deficiency * Roles in the reproductive system * Interactions with pathogens * Exploitation for therapy * Complement regulators in other species Includes bibliographical references (pages 261-370) and index |
| Beschreibung: | xiv, 382 pages |
| ISBN: | 9780125069656 0125069650 9781429498388 1429498382 0080529569 9780080529561 128103729X 9781281037299 |
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| 245 | 1 | 0 | |a Complement regulatory proteins |c B. Paul Morgan and Claire L. Harris |
| 264 | 1 | |a San Diego |b Academic Press |c ©1999 | |
| 300 | |a xiv, 382 pages | ||
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| 337 | |b c |2 rdamedia | ||
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| 500 | |a From small beginnings in the early 1970s, the study of complement regulatory proteins has grown in the last decade to the point where it dominates the complement field. This growth has been fueled by the discovery of new regulators, the cloning of old and new regulators, the discovery that many of the regulators are structurally and evolutionarily related to each other and the development of recombinant forms for use in therapy. There are now more proteins known to be involved in controlling the complement system than there are components of the system and the list continues to grow. The time is ripe for a comprehensive review of our current knowledge of these intriguing proteins. This book does just that. The first few chapters discuss the "nuts-and-bolts" of the complement regulators, describing their structures, functional roles and modes of action. | ||
| 500 | |a The roles of the complement regulators in vivo are then described, focusing on the consequences of deficiency, roles in the reproductive system, interactions with pathogens and exploitation for therapy. The interesting developments in defining the complement regulators expressed in other species are also discussed. The book is written as a monograph, albeit by two people. The text is as readable as possible without compromising on scientific accuracy and completeness. The conversational style very evident in some sections is deliberate! Placing all references in a single bibliography at the end of the text further improves readability. The reader will go to the book to discover a specific fact but be persuaded to read more and derive pleasure from the process. The authors' enthusiasm for the subject comes over strongly in the text, and this enthusiasm proves infectious. | ||
| 500 | |a Key Features * Complement regulators--structure, functional roles and mode of action * Comprehensive reviews of each of the individual regulators * Roles of Complement regulators in vivo, in health and disease: * Consequences of deficiency * Roles in the reproductive system * Interactions with pathogens * Exploitation for therapy * Complement regulators in other species | ||
| 500 | |a Includes bibliographical references (pages 261-370) and index | ||
| 650 | 4 | |a Complement System Proteins | |
| 650 | 4 | |a Membrane Proteins | |
| 650 | 4 | |a Blood proteins | |
| 650 | 7 | |a MEDICAL / Immunology |2 bisacsh | |
| 650 | 7 | |a Complement (Immunology) |2 fast | |
| 650 | 4 | |a Medizin | |
| 650 | 4 | |a Complement (Immunology) | |
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| 689 | 0 | |8 1\p |5 DE-604 | |
| 700 | 1 | |a Harris, Claire L. |e Sonstige |4 oth | |
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Datensatz im Suchindex
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| author | Morgan, B. Paul |
| author_facet | Morgan, B. Paul |
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| author_sort | Morgan, B. Paul |
| author_variant | b p m bp bpm |
| building | Verbundindex |
| bvnumber | BV044383835 |
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| dewey-full | 616.07/997 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.07/997 |
| dewey-search | 616.07/997 |
| dewey-sort | 3616.07 3997 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
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| institution | BVB |
| isbn | 9780125069656 0125069650 9781429498388 1429498382 0080529569 9780080529561 128103729X 9781281037299 |
| language | English |
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| physical | xiv, 382 pages |
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| publishDate | 1999 |
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| publisher | Academic Press |
| record_format | marc |
| spelling | Morgan, B. Paul Verfasser aut Complement regulatory proteins B. Paul Morgan and Claire L. Harris San Diego Academic Press ©1999 xiv, 382 pages txt rdacontent c rdamedia cr rdacarrier From small beginnings in the early 1970s, the study of complement regulatory proteins has grown in the last decade to the point where it dominates the complement field. This growth has been fueled by the discovery of new regulators, the cloning of old and new regulators, the discovery that many of the regulators are structurally and evolutionarily related to each other and the development of recombinant forms for use in therapy. There are now more proteins known to be involved in controlling the complement system than there are components of the system and the list continues to grow. The time is ripe for a comprehensive review of our current knowledge of these intriguing proteins. This book does just that. The first few chapters discuss the "nuts-and-bolts" of the complement regulators, describing their structures, functional roles and modes of action. The roles of the complement regulators in vivo are then described, focusing on the consequences of deficiency, roles in the reproductive system, interactions with pathogens and exploitation for therapy. The interesting developments in defining the complement regulators expressed in other species are also discussed. The book is written as a monograph, albeit by two people. The text is as readable as possible without compromising on scientific accuracy and completeness. The conversational style very evident in some sections is deliberate! Placing all references in a single bibliography at the end of the text further improves readability. The reader will go to the book to discover a specific fact but be persuaded to read more and derive pleasure from the process. The authors' enthusiasm for the subject comes over strongly in the text, and this enthusiasm proves infectious. Key Features * Complement regulators--structure, functional roles and mode of action * Comprehensive reviews of each of the individual regulators * Roles of Complement regulators in vivo, in health and disease: * Consequences of deficiency * Roles in the reproductive system * Interactions with pathogens * Exploitation for therapy * Complement regulators in other species Includes bibliographical references (pages 261-370) and index Complement System Proteins Membrane Proteins Blood proteins MEDICAL / Immunology bisacsh Complement (Immunology) fast Medizin Complement (Immunology) Komplement Immunologie (DE-588)4120589-3 gnd rswk-swf Komplement Immunologie (DE-588)4120589-3 s 1\p DE-604 Harris, Claire L. Sonstige oth http://www.sciencedirect.com/science/book/9780125069656 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Morgan, B. Paul Complement regulatory proteins Complement System Proteins Membrane Proteins Blood proteins MEDICAL / Immunology bisacsh Complement (Immunology) fast Medizin Complement (Immunology) Komplement Immunologie (DE-588)4120589-3 gnd |
| subject_GND | (DE-588)4120589-3 |
| title | Complement regulatory proteins |
| title_auth | Complement regulatory proteins |
| title_exact_search | Complement regulatory proteins |
| title_full | Complement regulatory proteins B. Paul Morgan and Claire L. Harris |
| title_fullStr | Complement regulatory proteins B. Paul Morgan and Claire L. Harris |
| title_full_unstemmed | Complement regulatory proteins B. Paul Morgan and Claire L. Harris |
| title_short | Complement regulatory proteins |
| title_sort | complement regulatory proteins |
| topic | Complement System Proteins Membrane Proteins Blood proteins MEDICAL / Immunology bisacsh Complement (Immunology) fast Medizin Complement (Immunology) Komplement Immunologie (DE-588)4120589-3 gnd |
| topic_facet | Complement System Proteins Membrane Proteins Blood proteins MEDICAL / Immunology Complement (Immunology) Medizin Komplement Immunologie |
| url | http://www.sciencedirect.com/science/book/9780125069656 |
| work_keys_str_mv | AT morganbpaul complementregulatoryproteins AT harrisclairel complementregulatoryproteins |