Biochemistry of collagens: structure, function and biomarkers
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
London, United Kingdom
Academic Press
c2016
|
| Schlagworte: | |
| Online-Zugang: | BTU01 FAW01 Volltext |
| Beschreibung: | Includes index Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers provides a comprehensive introduction to collagen and structural proteins. Type I collagen is one of the most abundant molecules in the body, playing essential roles in different tissues, particularly bone and skin. A key aspect of type I collagen is its post-translational modifications which are essential for correct synthesis and structural integrity of collagens, for tissue-specific functionality, as well as for application as biomarkers of different pathologies. This volume summarizes current data on key structural proteins (collagens, laminins and elastin), reviews how these molecules affect pathologies, and describes selected modifications of proteins that result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the ECM harbor cryptic signaling functions that may be viewed as endocrine functions. Additionally, it highlights how this knowledge can be exploited to modulate fibrotic disease |
| Beschreibung: | 1 Online ressource (xxxiv, 238 pages) |
| ISBN: | 0128098996 9780128098998 9780128098479 0128098473 |
Internformat
MARC
| LEADER | 00000nmm a2200000zc 4500 | ||
|---|---|---|---|
| 001 | BV044383419 | ||
| 003 | DE-604 | ||
| 005 | 20200604 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 170630s2016 |||| o||u| ||||||eng d | ||
| 020 | |a 0128098996 |9 0-12-809899-6 | ||
| 020 | |a 9780128098998 |9 978-0-12-809899-8 | ||
| 020 | |a 9780128098479 |9 978-0-12-809847-9 | ||
| 020 | |a 0128098473 |9 0-12-809847-3 | ||
| 035 | |a (ZDB-33-ESD)ocn955139533 | ||
| 035 | |a (OCoLC)955139533 | ||
| 035 | |a (DE-599)BVBBV044383419 | ||
| 040 | |a DE-604 |b ger |e aacr | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-1046 |a DE-634 | ||
| 082 | 0 | |a 572/.67 |2 23 | |
| 245 | 1 | 0 | |a Biochemistry of collagens |b structure, function and biomarkers |c edited by Morten A. Karsdal ; co-editors: Diana J. Leeming, Kim Henriksen, Anne-Christine Bay-Jensen |
| 264 | 1 | |a London, United Kingdom |b Academic Press |c c2016 | |
| 300 | |a 1 Online ressource (xxxiv, 238 pages) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 500 | |a Includes index | ||
| 500 | |a Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers provides a comprehensive introduction to collagen and structural proteins. Type I collagen is one of the most abundant molecules in the body, playing essential roles in different tissues, particularly bone and skin. A key aspect of type I collagen is its post-translational modifications which are essential for correct synthesis and structural integrity of collagens, for tissue-specific functionality, as well as for application as biomarkers of different pathologies. This volume summarizes current data on key structural proteins (collagens, laminins and elastin), reviews how these molecules affect pathologies, and describes selected modifications of proteins that result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the ECM harbor cryptic signaling functions that may be viewed as endocrine functions. Additionally, it highlights how this knowledge can be exploited to modulate fibrotic disease | ||
| 650 | 7 | |a Collagen |2 fast | |
| 650 | 4 | |a Collagen | |
| 650 | 0 | 7 | |a Laminin |0 (DE-588)4197625-3 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Kollagen |0 (DE-588)4164652-6 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Elastin |0 (DE-588)4151680-1 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Biochemie |0 (DE-588)4006777-4 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Biochemie |0 (DE-588)4006777-4 |D s |
| 689 | 0 | 1 | |a Kollagen |0 (DE-588)4164652-6 |D s |
| 689 | 0 | 2 | |a Laminin |0 (DE-588)4197625-3 |D s |
| 689 | 0 | 3 | |a Elastin |0 (DE-588)4151680-1 |D s |
| 689 | 0 | |5 DE-604 | |
| 700 | 1 | |a Karsdal, Morten |e Sonstige |4 oth | |
| 856 | 4 | 0 | |u http://www.sciencedirect.com/science/book/9780128098479 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
| 912 | |a ZDB-33-ESD |a ZDB-33-EBS | ||
| 999 | |a oai:aleph.bib-bvb.de:BVB01-029785640 | ||
| 966 | e | |u http://www.sciencedirect.com/science/book/9780128098479 |l BTU01 |p ZDB-33-EBS |q BTU_PDA_EBS_Kauf |x Verlag |3 Volltext | |
| 966 | e | |u http://www.sciencedirect.com/science/book/9780128098479 |l FAW01 |p ZDB-33-ESD |q FAW_PDA_ESD |x Verlag |3 Volltext | |
Datensatz im Suchindex
| _version_ | 1804177648587374592 |
|---|---|
| any_adam_object | |
| building | Verbundindex |
| bvnumber | BV044383419 |
| collection | ZDB-33-ESD ZDB-33-EBS |
| ctrlnum | (ZDB-33-ESD)ocn955139533 (OCoLC)955139533 (DE-599)BVBBV044383419 |
| dewey-full | 572/.67 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 572 - Biochemistry |
| dewey-raw | 572/.67 |
| dewey-search | 572/.67 |
| dewey-sort | 3572 267 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03137nmm a2200517zc 4500</leader><controlfield tag="001">BV044383419</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20200604 </controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">170630s2016 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">0128098996</subfield><subfield code="9">0-12-809899-6</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9780128098998</subfield><subfield code="9">978-0-12-809899-8</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9780128098479</subfield><subfield code="9">978-0-12-809847-9</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">0128098473</subfield><subfield code="9">0-12-809847-3</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-33-ESD)ocn955139533</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)955139533</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV044383419</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-1046</subfield><subfield code="a">DE-634</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">572/.67</subfield><subfield code="2">23</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Biochemistry of collagens</subfield><subfield code="b">structure, function and biomarkers</subfield><subfield code="c">edited by Morten A. Karsdal ; co-editors: Diana J. Leeming, Kim Henriksen, Anne-Christine Bay-Jensen</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">London, United Kingdom</subfield><subfield code="b">Academic Press</subfield><subfield code="c">c2016</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online ressource (xxxiv, 238 pages)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Includes index</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers provides a comprehensive introduction to collagen and structural proteins. Type I collagen is one of the most abundant molecules in the body, playing essential roles in different tissues, particularly bone and skin. A key aspect of type I collagen is its post-translational modifications which are essential for correct synthesis and structural integrity of collagens, for tissue-specific functionality, as well as for application as biomarkers of different pathologies. This volume summarizes current data on key structural proteins (collagens, laminins and elastin), reviews how these molecules affect pathologies, and describes selected modifications of proteins that result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the ECM harbor cryptic signaling functions that may be viewed as endocrine functions. Additionally, it highlights how this knowledge can be exploited to modulate fibrotic disease</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Collagen</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Collagen</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Laminin</subfield><subfield code="0">(DE-588)4197625-3</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Kollagen</subfield><subfield code="0">(DE-588)4164652-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Elastin</subfield><subfield code="0">(DE-588)4151680-1</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Biochemie</subfield><subfield code="0">(DE-588)4006777-4</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Biochemie</subfield><subfield code="0">(DE-588)4006777-4</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Kollagen</subfield><subfield code="0">(DE-588)4164652-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="2"><subfield code="a">Laminin</subfield><subfield code="0">(DE-588)4197625-3</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="3"><subfield code="a">Elastin</subfield><subfield code="0">(DE-588)4151680-1</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Karsdal, Morten</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://www.sciencedirect.com/science/book/9780128098479</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-33-ESD</subfield><subfield code="a">ZDB-33-EBS</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-029785640</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">http://www.sciencedirect.com/science/book/9780128098479</subfield><subfield code="l">BTU01</subfield><subfield code="p">ZDB-33-EBS</subfield><subfield code="q">BTU_PDA_EBS_Kauf</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">http://www.sciencedirect.com/science/book/9780128098479</subfield><subfield code="l">FAW01</subfield><subfield code="p">ZDB-33-ESD</subfield><subfield code="q">FAW_PDA_ESD</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| id | DE-604.BV044383419 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:51:25Z |
| institution | BVB |
| isbn | 0128098996 9780128098998 9780128098479 0128098473 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-029785640 |
| oclc_num | 955139533 |
| open_access_boolean | |
| owner | DE-1046 DE-634 |
| owner_facet | DE-1046 DE-634 |
| physical | 1 Online ressource (xxxiv, 238 pages) |
| psigel | ZDB-33-ESD ZDB-33-EBS ZDB-33-EBS BTU_PDA_EBS_Kauf ZDB-33-ESD FAW_PDA_ESD |
| publishDate | 2016 |
| publishDateSearch | 2016 |
| publishDateSort | 2016 |
| publisher | Academic Press |
| record_format | marc |
| spelling | Biochemistry of collagens structure, function and biomarkers edited by Morten A. Karsdal ; co-editors: Diana J. Leeming, Kim Henriksen, Anne-Christine Bay-Jensen London, United Kingdom Academic Press c2016 1 Online ressource (xxxiv, 238 pages) txt rdacontent c rdamedia cr rdacarrier Includes index Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers provides a comprehensive introduction to collagen and structural proteins. Type I collagen is one of the most abundant molecules in the body, playing essential roles in different tissues, particularly bone and skin. A key aspect of type I collagen is its post-translational modifications which are essential for correct synthesis and structural integrity of collagens, for tissue-specific functionality, as well as for application as biomarkers of different pathologies. This volume summarizes current data on key structural proteins (collagens, laminins and elastin), reviews how these molecules affect pathologies, and describes selected modifications of proteins that result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the ECM harbor cryptic signaling functions that may be viewed as endocrine functions. Additionally, it highlights how this knowledge can be exploited to modulate fibrotic disease Collagen fast Collagen Laminin (DE-588)4197625-3 gnd rswk-swf Kollagen (DE-588)4164652-6 gnd rswk-swf Elastin (DE-588)4151680-1 gnd rswk-swf Biochemie (DE-588)4006777-4 gnd rswk-swf Biochemie (DE-588)4006777-4 s Kollagen (DE-588)4164652-6 s Laminin (DE-588)4197625-3 s Elastin (DE-588)4151680-1 s DE-604 Karsdal, Morten Sonstige oth http://www.sciencedirect.com/science/book/9780128098479 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Biochemistry of collagens structure, function and biomarkers Collagen fast Collagen Laminin (DE-588)4197625-3 gnd Kollagen (DE-588)4164652-6 gnd Elastin (DE-588)4151680-1 gnd Biochemie (DE-588)4006777-4 gnd |
| subject_GND | (DE-588)4197625-3 (DE-588)4164652-6 (DE-588)4151680-1 (DE-588)4006777-4 |
| title | Biochemistry of collagens structure, function and biomarkers |
| title_auth | Biochemistry of collagens structure, function and biomarkers |
| title_exact_search | Biochemistry of collagens structure, function and biomarkers |
| title_full | Biochemistry of collagens structure, function and biomarkers edited by Morten A. Karsdal ; co-editors: Diana J. Leeming, Kim Henriksen, Anne-Christine Bay-Jensen |
| title_fullStr | Biochemistry of collagens structure, function and biomarkers edited by Morten A. Karsdal ; co-editors: Diana J. Leeming, Kim Henriksen, Anne-Christine Bay-Jensen |
| title_full_unstemmed | Biochemistry of collagens structure, function and biomarkers edited by Morten A. Karsdal ; co-editors: Diana J. Leeming, Kim Henriksen, Anne-Christine Bay-Jensen |
| title_short | Biochemistry of collagens |
| title_sort | biochemistry of collagens structure function and biomarkers |
| title_sub | structure, function and biomarkers |
| topic | Collagen fast Collagen Laminin (DE-588)4197625-3 gnd Kollagen (DE-588)4164652-6 gnd Elastin (DE-588)4151680-1 gnd Biochemie (DE-588)4006777-4 gnd |
| topic_facet | Collagen Laminin Kollagen Elastin Biochemie |
| url | http://www.sciencedirect.com/science/book/9780128098479 |
| work_keys_str_mv | AT karsdalmorten biochemistryofcollagensstructurefunctionandbiomarkers |