Stem cell bioprocessing: for cellular therapy, diagnostics and drug development
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Witney, UK
Biohealthcare
2013
|
| Schriftenreihe: | Biohealthcare Publishing series on pharma, biotech and biosciences
no. 33 |
| Schlagworte: | |
| Online-Zugang: | DE-1046 URL des Erstveröffentlichers |
| Beschreibung: | Stem cell bioprocessing describes the main large-scale bioprocessing strategies for both stem cell culture and purification, envisaging the application of these cells for regenerative medicine and drug screening. Bioreactor configurations are described, including their applications for stem cell expansion, and stem cell separation techniques such as isolation and purification are discussed. Basic definitions are provided concerning the different types of stem cells, from adult stem cells to the more recent induced pluripotent stem cells. The main characteristics of these different stem cell types are described, alongside the molecular mechanisms underlying their self-renewal and differentiation. The book also focuses on methodologies currently used for in vitro stem cell culture under static conditions, including the challenge of xeno-free culture conditions, as well as culture parameters that influence stem cell culture. Approaches for both stem cell culture and separation in micro-scale conditions are presented, including the use of cellular microarrays for high-throughput screening of the effect of both soluble and extracellular matrix molecules. A further section is dedicated to application of stem cells for regenerative medicine. Maintains a unique focus on both the basic stem cell biology concepts, and their translation to large-scale bioprocessing approachesEnvisages the use of stem cells in regenerative medicine and drug screening applicationsDiscusses the application of microscale techniques as a tool to perform basic stem cell biology studies |
| Beschreibung: | 250 pages |
| ISBN: | 1907568883 9781907568886 9781306177016 1306177014 |
Internformat
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Datensatz im Suchindex
| _version_ | 1816805427508150273 |
|---|---|
| adam_text | |
| any_adam_object | |
| author | Fernandes, Tiago G. |
| author_facet | Fernandes, Tiago G. |
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| author_sort | Fernandes, Tiago G. |
| author_variant | t g f tg tgf |
| building | Verbundindex |
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| dewey-full | 616/.02774 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
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| dewey-search | 616/.02774 |
| dewey-sort | 3616 42774 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
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| id | DE-604.BV044383301 |
| illustrated | Not Illustrated |
| indexdate | 2024-11-26T17:04:34Z |
| institution | BVB |
| isbn | 1907568883 9781907568886 9781306177016 1306177014 |
| language | English |
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| physical | 250 pages |
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| publisher | Biohealthcare |
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| series2 | Biohealthcare Publishing series on pharma, biotech and biosciences |
| spelling | Fernandes, Tiago G. Verfasser aut Stem cell bioprocessing for cellular therapy, diagnostics and drug development Tiago G. Fernandes, Maria Margarida Diogo and Joaquim M.S. Cabral Witney, UK Biohealthcare 2013 250 pages txt rdacontent c rdamedia cr rdacarrier Biohealthcare Publishing series on pharma, biotech and biosciences no. 33 Stem cell bioprocessing describes the main large-scale bioprocessing strategies for both stem cell culture and purification, envisaging the application of these cells for regenerative medicine and drug screening. Bioreactor configurations are described, including their applications for stem cell expansion, and stem cell separation techniques such as isolation and purification are discussed. Basic definitions are provided concerning the different types of stem cells, from adult stem cells to the more recent induced pluripotent stem cells. The main characteristics of these different stem cell types are described, alongside the molecular mechanisms underlying their self-renewal and differentiation. The book also focuses on methodologies currently used for in vitro stem cell culture under static conditions, including the challenge of xeno-free culture conditions, as well as culture parameters that influence stem cell culture. Approaches for both stem cell culture and separation in micro-scale conditions are presented, including the use of cellular microarrays for high-throughput screening of the effect of both soluble and extracellular matrix molecules. A further section is dedicated to application of stem cells for regenerative medicine. Maintains a unique focus on both the basic stem cell biology concepts, and their translation to large-scale bioprocessing approachesEnvisages the use of stem cells in regenerative medicine and drug screening applicationsDiscusses the application of microscale techniques as a tool to perform basic stem cell biology studies Biotechnology / Materials fast Stem cells fast Stem cells Biotechnology Materials Arzneimittelentwicklung (DE-588)4143176-5 gnd rswk-swf Periphere Stammzellentransplantation (DE-588)4432541-1 gnd rswk-swf Stammzelle (DE-588)4665329-6 gnd rswk-swf Bioverfahrenstechnik (DE-588)4307166-1 gnd rswk-swf Stammzelle (DE-588)4665329-6 s Bioverfahrenstechnik (DE-588)4307166-1 s Periphere Stammzellentransplantation (DE-588)4432541-1 s Arzneimittelentwicklung (DE-588)4143176-5 s 1\p DE-604 Diogo, Maria Margarida Sonstige oth Cabral, Joaquim S. Sonstige oth http://www.sciencedirect.com/science/book/9781907568886 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Fernandes, Tiago G. Stem cell bioprocessing for cellular therapy, diagnostics and drug development Biotechnology / Materials fast Stem cells fast Stem cells Biotechnology Materials Arzneimittelentwicklung (DE-588)4143176-5 gnd Periphere Stammzellentransplantation (DE-588)4432541-1 gnd Stammzelle (DE-588)4665329-6 gnd Bioverfahrenstechnik (DE-588)4307166-1 gnd |
| subject_GND | (DE-588)4143176-5 (DE-588)4432541-1 (DE-588)4665329-6 (DE-588)4307166-1 |
| title | Stem cell bioprocessing for cellular therapy, diagnostics and drug development |
| title_auth | Stem cell bioprocessing for cellular therapy, diagnostics and drug development |
| title_exact_search | Stem cell bioprocessing for cellular therapy, diagnostics and drug development |
| title_full | Stem cell bioprocessing for cellular therapy, diagnostics and drug development Tiago G. Fernandes, Maria Margarida Diogo and Joaquim M.S. Cabral |
| title_fullStr | Stem cell bioprocessing for cellular therapy, diagnostics and drug development Tiago G. Fernandes, Maria Margarida Diogo and Joaquim M.S. Cabral |
| title_full_unstemmed | Stem cell bioprocessing for cellular therapy, diagnostics and drug development Tiago G. Fernandes, Maria Margarida Diogo and Joaquim M.S. Cabral |
| title_short | Stem cell bioprocessing |
| title_sort | stem cell bioprocessing for cellular therapy diagnostics and drug development |
| title_sub | for cellular therapy, diagnostics and drug development |
| topic | Biotechnology / Materials fast Stem cells fast Stem cells Biotechnology Materials Arzneimittelentwicklung (DE-588)4143176-5 gnd Periphere Stammzellentransplantation (DE-588)4432541-1 gnd Stammzelle (DE-588)4665329-6 gnd Bioverfahrenstechnik (DE-588)4307166-1 gnd |
| topic_facet | Biotechnology / Materials Stem cells Biotechnology Materials Arzneimittelentwicklung Periphere Stammzellentransplantation Stammzelle Bioverfahrenstechnik |
| url | http://www.sciencedirect.com/science/book/9781907568886 |
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