The glutamate synapse as a therapeutical target: molecular organization and pathology of the glutamate synapse
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam
Elsevier Science
1998
|
| Schriftenreihe: | Progress in brain research
v. 116 |
| Schlagworte: | |
| Online-Zugang: | FAW01 URL des Erstveröffentlichers |
| Beschreibung: | This volume provides a comprehensive update on basic glutamate research, from a clinical perspective. Thus, emphasis is placed on how the different molecular players at the glutamate synapse interact to produce a postsynaptic response, how synaptic transmission is perturbed in epilepsy and other pathological conditions, and how glutamate may acquire toxic properties and lead to acute or chronic neurodegeneration. Promising targets for therapeutic strategies are discussed. A coherent picture is provided of the glutamate synapse and its molecular organization. The book therefore deals with each step in the signal process, from synthesis and vesicular uptake of glutamate to its clearance following receptor activation Includes bibliographical references and index |
| Beschreibung: | xii, 462 pages |
| ISBN: | 0444827544 9780444827548 |
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| indexdate | 2024-07-10T07:51:24Z |
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| series2 | Progress in brain research |
| spelling | The glutamate synapse as a therapeutical target molecular organization and pathology of the glutamate synapse edited by O.P. Ottersen, I.A. Langmoen, L. Gjerstad Amsterdam Elsevier Science 1998 xii, 462 pages txt rdacontent c rdamedia cr rdacarrier Progress in brain research v. 116 This volume provides a comprehensive update on basic glutamate research, from a clinical perspective. Thus, emphasis is placed on how the different molecular players at the glutamate synapse interact to produce a postsynaptic response, how synaptic transmission is perturbed in epilepsy and other pathological conditions, and how glutamate may acquire toxic properties and lead to acute or chronic neurodegeneration. Promising targets for therapeutic strategies are discussed. A coherent picture is provided of the glutamate synapse and its molecular organization. The book therefore deals with each step in the signal process, from synthesis and vesicular uptake of glutamate to its clearance following receptor activation Includes bibliographical references and index Glutamic acid Receptors Effect of drugs on Epilepsy Molecular aspects Epilepsy Chemotherapy Exzitatorische Synapse (DE-588)4381196-6 gnd rswk-swf Pharmakotherapie (DE-588)4076066-2 gnd rswk-swf Neurochemie (DE-588)4041872-8 gnd rswk-swf Glutamatrezeptor (DE-588)4325632-6 gnd rswk-swf Glutamate (DE-588)4157708-5 gnd rswk-swf Zentralnervensystem (DE-588)4067637-7 gnd rswk-swf Synaptische Transmission (DE-588)4331218-4 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Exzitatorische Synapse (DE-588)4381196-6 s Glutamate (DE-588)4157708-5 s Pharmakotherapie (DE-588)4076066-2 s 2\p DE-604 Zentralnervensystem (DE-588)4067637-7 s Neurochemie (DE-588)4041872-8 s 3\p DE-604 Synaptische Transmission (DE-588)4331218-4 s 4\p DE-604 Glutamatrezeptor (DE-588)4325632-6 s 5\p DE-604 Ottersen, O. P. Sonstige (DE-588)1169611575 oth Langmoen, Iver Arne Sonstige oth Gjerstad, L. Sonstige oth http://www.sciencedirect.com/science/bookseries/00796123/116 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 3\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 4\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 5\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | The glutamate synapse as a therapeutical target molecular organization and pathology of the glutamate synapse Glutamic acid Receptors Effect of drugs on Epilepsy Molecular aspects Epilepsy Chemotherapy Exzitatorische Synapse (DE-588)4381196-6 gnd Pharmakotherapie (DE-588)4076066-2 gnd Neurochemie (DE-588)4041872-8 gnd Glutamatrezeptor (DE-588)4325632-6 gnd Glutamate (DE-588)4157708-5 gnd Zentralnervensystem (DE-588)4067637-7 gnd Synaptische Transmission (DE-588)4331218-4 gnd |
| subject_GND | (DE-588)4381196-6 (DE-588)4076066-2 (DE-588)4041872-8 (DE-588)4325632-6 (DE-588)4157708-5 (DE-588)4067637-7 (DE-588)4331218-4 (DE-588)4143413-4 |
| title | The glutamate synapse as a therapeutical target molecular organization and pathology of the glutamate synapse |
| title_auth | The glutamate synapse as a therapeutical target molecular organization and pathology of the glutamate synapse |
| title_exact_search | The glutamate synapse as a therapeutical target molecular organization and pathology of the glutamate synapse |
| title_full | The glutamate synapse as a therapeutical target molecular organization and pathology of the glutamate synapse edited by O.P. Ottersen, I.A. Langmoen, L. Gjerstad |
| title_fullStr | The glutamate synapse as a therapeutical target molecular organization and pathology of the glutamate synapse edited by O.P. Ottersen, I.A. Langmoen, L. Gjerstad |
| title_full_unstemmed | The glutamate synapse as a therapeutical target molecular organization and pathology of the glutamate synapse edited by O.P. Ottersen, I.A. Langmoen, L. Gjerstad |
| title_short | The glutamate synapse as a therapeutical target |
| title_sort | the glutamate synapse as a therapeutical target molecular organization and pathology of the glutamate synapse |
| title_sub | molecular organization and pathology of the glutamate synapse |
| topic | Glutamic acid Receptors Effect of drugs on Epilepsy Molecular aspects Epilepsy Chemotherapy Exzitatorische Synapse (DE-588)4381196-6 gnd Pharmakotherapie (DE-588)4076066-2 gnd Neurochemie (DE-588)4041872-8 gnd Glutamatrezeptor (DE-588)4325632-6 gnd Glutamate (DE-588)4157708-5 gnd Zentralnervensystem (DE-588)4067637-7 gnd Synaptische Transmission (DE-588)4331218-4 gnd |
| topic_facet | Glutamic acid Receptors Effect of drugs on Epilepsy Molecular aspects Epilepsy Chemotherapy Exzitatorische Synapse Pharmakotherapie Neurochemie Glutamatrezeptor Glutamate Zentralnervensystem Synaptische Transmission Aufsatzsammlung |
| url | http://www.sciencedirect.com/science/bookseries/00796123/116 |
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