Pharmacology of G protein coupled receptors:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
San Diego, CA
Elsevier
©2011
|
| Schriftenreihe: | Advances in pharmacology (San Diego, Calif.)
v. 62 |
| Schlagworte: | |
| Online-Zugang: | FAW01 Volltext |
| Beschreibung: | Includes bibliographical references and index G protein coupled receptors remain the most important class of therapeutic targets in medicine. In the last 5 years, tremendous advances have been made in our understanding of the structure and mechanism of this critical family of drug targets. The present volume explores the modern experimental and conceptual framework for drug discovery for G protein coupled receptors. It explores advances in structure determination and structure-based drug design as well as new concepts of allosteric modulation, functional selectivity/biased agonism, and pharmacological chaperones. In addition, emerging drug targets such as receptor families for fatty acids, carboxylic acids, lipid mediators, etc. are included. Final chapters cover novel mechanisms of signal regulation through PDZ domains and RGS proteins. This volume will bring an up-to-date perspective on the G protein coupled receptor field to both academic and industry scientists. The present volume explores the modern experimental and conceptual framework for drug discovery for G protein coupled receptors. It explores advances in structure determination and structure-based drug design as well as new concepts of allosteric modulation, functional selectivity/biased agonism, and pharmacological chaperones. This volume will bring an up-to-date perspective on the G protein coupled receptor field to both academic and industry scientists |
| Beschreibung: | xvi, 270 pages |
| ISBN: | 9780123859525 0123859522 |
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| 500 | |a G protein coupled receptors remain the most important class of therapeutic targets in medicine. In the last 5 years, tremendous advances have been made in our understanding of the structure and mechanism of this critical family of drug targets. The present volume explores the modern experimental and conceptual framework for drug discovery for G protein coupled receptors. It explores advances in structure determination and structure-based drug design as well as new concepts of allosteric modulation, functional selectivity/biased agonism, and pharmacological chaperones. In addition, emerging drug targets such as receptor families for fatty acids, carboxylic acids, lipid mediators, etc. are included. Final chapters cover novel mechanisms of signal regulation through PDZ domains and RGS proteins. This volume will bring an up-to-date perspective on the G protein coupled receptor field to both academic and industry scientists. The present volume explores the modern experimental and conceptual framework for drug discovery for G protein coupled receptors. It explores advances in structure determination and structure-based drug design as well as new concepts of allosteric modulation, functional selectivity/biased agonism, and pharmacological chaperones. This volume will bring an up-to-date perspective on the G protein coupled receptor field to both academic and industry scientists | ||
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| indexdate | 2024-07-10T07:51:23Z |
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| isbn | 9780123859525 0123859522 |
| language | English |
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| series2 | Advances in pharmacology (San Diego, Calif.) |
| spelling | Pharmacology of G protein coupled receptors edited by Richard R. Neubig San Diego, CA Elsevier ©2011 xvi, 270 pages txt rdacontent c rdamedia cr rdacarrier Advances in pharmacology (San Diego, Calif.) v. 62 Includes bibliographical references and index G protein coupled receptors remain the most important class of therapeutic targets in medicine. In the last 5 years, tremendous advances have been made in our understanding of the structure and mechanism of this critical family of drug targets. The present volume explores the modern experimental and conceptual framework for drug discovery for G protein coupled receptors. It explores advances in structure determination and structure-based drug design as well as new concepts of allosteric modulation, functional selectivity/biased agonism, and pharmacological chaperones. In addition, emerging drug targets such as receptor families for fatty acids, carboxylic acids, lipid mediators, etc. are included. Final chapters cover novel mechanisms of signal regulation through PDZ domains and RGS proteins. This volume will bring an up-to-date perspective on the G protein coupled receptor field to both academic and industry scientists. The present volume explores the modern experimental and conceptual framework for drug discovery for G protein coupled receptors. It explores advances in structure determination and structure-based drug design as well as new concepts of allosteric modulation, functional selectivity/biased agonism, and pharmacological chaperones. This volume will bring an up-to-date perspective on the G protein coupled receptor field to both academic and industry scientists Biochemistry fast Cell receptors fast G proteins fast G proteins Cell receptors Biochemistry Neubig, Richard R. Sonstige oth http://www.sciencedirect.com/science/bookseries/10543589/62 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Pharmacology of G protein coupled receptors Biochemistry fast Cell receptors fast G proteins fast G proteins Cell receptors Biochemistry |
| title | Pharmacology of G protein coupled receptors |
| title_auth | Pharmacology of G protein coupled receptors |
| title_exact_search | Pharmacology of G protein coupled receptors |
| title_full | Pharmacology of G protein coupled receptors edited by Richard R. Neubig |
| title_fullStr | Pharmacology of G protein coupled receptors edited by Richard R. Neubig |
| title_full_unstemmed | Pharmacology of G protein coupled receptors edited by Richard R. Neubig |
| title_short | Pharmacology of G protein coupled receptors |
| title_sort | pharmacology of g protein coupled receptors |
| topic | Biochemistry fast Cell receptors fast G proteins fast G proteins Cell receptors Biochemistry |
| topic_facet | Biochemistry Cell receptors G proteins |
| url | http://www.sciencedirect.com/science/bookseries/10543589/62 |
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