Acute lung injury: epidemiology, health effects and therapeutic treatment strategies
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, New York
Nova Science Publishers, Inc.
2014
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| Schriftenreihe: | Pulmonary and Respiratory Diseases and Disorders
|
| Schlagworte: | |
| Beschreibung: | Print version record |
| Beschreibung: | 1 online resource (98 pages) illustrations |
| ISBN: | 9781633218697 1633218694 |
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| 505 | 8 | |a ACUTE LUNG INJURY: EPIDEMIOLOGY, HEALTH EFFECTS AND THERAPEUTIC TREATMENT STRATEGIES; ACUTE LUNG INJURY: EPIDEMIOLOGY, HEALTH EFFECTS AND THERAPEUTIC TREATMENT STRATEGIES; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter 1: TRALI Not a Two Hit, But a Multi-Causal Model; Center for Clinical Transfusion Research, Sanquin Research, Leiden; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands; Abstract; Introduction; Threshold Models; A More General Threshold Model of Multi-Causality; The Sufficient Cause Model; Discussion | |
| 505 | 8 | |a ConclusionReferences; Chapter 2: Mechanisms and Prevention of Pulmonary Microvascular Hyperpermeability in Acute Lung Injury; Abstract; Introduction; Pulmonary Microvascular Hyperpermeability; in Acute Lung Injury; The Mechanisms of Pulmonary Microvascular Hyperpermeability in Acute Lung Injury; Macrophages; Neutrophils; Platelets; Cell Organelles; Small G Protein; Calcium; HMGB1; Cell Junctions; Nitric Oxide (NO) and Inducible Nitric Oxide Synthase (iNOS); Focal Adhesions (FAs) Complex and FA Kinase (FAK); Hyperoxia; Prospective Approach to Heal ALI; References | |
| 505 | 8 | |a Chapter 3: Pharmacological Therapies for Acute Respiratory Distress SyndromeAbstract; Introduction; Corticosteroids; Neutrophil Elastase Inhibitors; Anticoagulant Therapies; Conclusion; References; Chapter 4: Novel Trends in Pharmacotherapy of Acute Lung Injury and Acute Respiratory Distress Syndrome; ABSTRACT; Definition of ALI/ARDS; Pathophysiology of ALI/ARDS as a Rationale for the Treatment; Pharmacotherapy of ALI/ARDS; Types, Dosage and Delivery of Exogenous Surfactants; Effects of Surfactant Administration; Complications of Surfactant Administration | |
| 505 | 8 | |a Surfactant Treatment in the Neonates and ChildrenSurfactant Treatment in the Adult Patients; Inhaled Nitric Oxide (iNO); Aerosolized Prostacyclin; Non-conventional Approaches (Cell and/or Gene Therapy); Cell-Based Approaches; Gene-Based Therapy; Cell-Delivered Gene Therapy; Conclusion; References; Editor Contact Information; Index | |
| 505 | 8 | |a In this book, authors review the current knowledge on acute lung injury (ALI). ALI/acute respiratory distress syndrome (ARDS) is characterized by diffuse alveolar damage, alveolar capillary leakage, lung edema, neutrophil-derived inflammation, and surfactant dysfunction. These changes lead to clinical manifestations of decreased lung compliance, severe hypoxemia, and bilateral pulmonary infiltrates. In the first chapter the authors describe how two different models of multi-causality (intuitively appealing threshold model and abstract sufficient cause model), both of which are commonly used in | |
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| 650 | 4 | |a Respiratory distress syndrome, Adult / Congresses | |
| 650 | 4 | |a Respiratory intensive care / Congresses | |
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| 650 | 7 | |a MEDICAL / Evidence-Based Medicine |2 bisacsh | |
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Datensatz im Suchindex
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| author | Mokra, Daniela |
| author_facet | Mokra, Daniela |
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| author_variant | d m dm |
| building | Verbundindex |
| bvnumber | BV044358616 |
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| contents | ACUTE LUNG INJURY: EPIDEMIOLOGY, HEALTH EFFECTS AND THERAPEUTIC TREATMENT STRATEGIES; ACUTE LUNG INJURY: EPIDEMIOLOGY, HEALTH EFFECTS AND THERAPEUTIC TREATMENT STRATEGIES; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter 1: TRALI Not a Two Hit, But a Multi-Causal Model; Center for Clinical Transfusion Research, Sanquin Research, Leiden; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands; Abstract; Introduction; Threshold Models; A More General Threshold Model of Multi-Causality; The Sufficient Cause Model; Discussion ConclusionReferences; Chapter 2: Mechanisms and Prevention of Pulmonary Microvascular Hyperpermeability in Acute Lung Injury; Abstract; Introduction; Pulmonary Microvascular Hyperpermeability; in Acute Lung Injury; The Mechanisms of Pulmonary Microvascular Hyperpermeability in Acute Lung Injury; Macrophages; Neutrophils; Platelets; Cell Organelles; Small G Protein; Calcium; HMGB1; Cell Junctions; Nitric Oxide (NO) and Inducible Nitric Oxide Synthase (iNOS); Focal Adhesions (FAs) Complex and FA Kinase (FAK); Hyperoxia; Prospective Approach to Heal ALI; References Chapter 3: Pharmacological Therapies for Acute Respiratory Distress SyndromeAbstract; Introduction; Corticosteroids; Neutrophil Elastase Inhibitors; Anticoagulant Therapies; Conclusion; References; Chapter 4: Novel Trends in Pharmacotherapy of Acute Lung Injury and Acute Respiratory Distress Syndrome; ABSTRACT; Definition of ALI/ARDS; Pathophysiology of ALI/ARDS as a Rationale for the Treatment; Pharmacotherapy of ALI/ARDS; Types, Dosage and Delivery of Exogenous Surfactants; Effects of Surfactant Administration; Complications of Surfactant Administration Surfactant Treatment in the Neonates and ChildrenSurfactant Treatment in the Adult Patients; Inhaled Nitric Oxide (iNO); Aerosolized Prostacyclin; Non-conventional Approaches (Cell and/or Gene Therapy); Cell-Based Approaches; Gene-Based Therapy; Cell-Delivered Gene Therapy; Conclusion; References; Editor Contact Information; Index In this book, authors review the current knowledge on acute lung injury (ALI). ALI/acute respiratory distress syndrome (ARDS) is characterized by diffuse alveolar damage, alveolar capillary leakage, lung edema, neutrophil-derived inflammation, and surfactant dysfunction. These changes lead to clinical manifestations of decreased lung compliance, severe hypoxemia, and bilateral pulmonary infiltrates. In the first chapter the authors describe how two different models of multi-causality (intuitively appealing threshold model and abstract sufficient cause model), both of which are commonly used in |
| ctrlnum | (ZDB-4-NLEBK)ocn891382815 (OCoLC)891382815 (DE-599)BVBBV044358616 |
| dewey-full | 616.24 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
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| discipline | Medizin |
| format | Electronic eBook |
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| spelling | Mokra, Daniela Verfasser aut Acute lung injury epidemiology, health effects and therapeutic treatment strategies Daniela Mokrá New York, New York Nova Science Publishers, Inc. 2014 © 2014 1 online resource (98 pages) illustrations txt rdacontent c rdamedia cr rdacarrier Pulmonary and Respiratory Diseases and Disorders Print version record ACUTE LUNG INJURY: EPIDEMIOLOGY, HEALTH EFFECTS AND THERAPEUTIC TREATMENT STRATEGIES; ACUTE LUNG INJURY: EPIDEMIOLOGY, HEALTH EFFECTS AND THERAPEUTIC TREATMENT STRATEGIES; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter 1: TRALI Not a Two Hit, But a Multi-Causal Model; Center for Clinical Transfusion Research, Sanquin Research, Leiden; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands; Abstract; Introduction; Threshold Models; A More General Threshold Model of Multi-Causality; The Sufficient Cause Model; Discussion ConclusionReferences; Chapter 2: Mechanisms and Prevention of Pulmonary Microvascular Hyperpermeability in Acute Lung Injury; Abstract; Introduction; Pulmonary Microvascular Hyperpermeability; in Acute Lung Injury; The Mechanisms of Pulmonary Microvascular Hyperpermeability in Acute Lung Injury; Macrophages; Neutrophils; Platelets; Cell Organelles; Small G Protein; Calcium; HMGB1; Cell Junctions; Nitric Oxide (NO) and Inducible Nitric Oxide Synthase (iNOS); Focal Adhesions (FAs) Complex and FA Kinase (FAK); Hyperoxia; Prospective Approach to Heal ALI; References Chapter 3: Pharmacological Therapies for Acute Respiratory Distress SyndromeAbstract; Introduction; Corticosteroids; Neutrophil Elastase Inhibitors; Anticoagulant Therapies; Conclusion; References; Chapter 4: Novel Trends in Pharmacotherapy of Acute Lung Injury and Acute Respiratory Distress Syndrome; ABSTRACT; Definition of ALI/ARDS; Pathophysiology of ALI/ARDS as a Rationale for the Treatment; Pharmacotherapy of ALI/ARDS; Types, Dosage and Delivery of Exogenous Surfactants; Effects of Surfactant Administration; Complications of Surfactant Administration Surfactant Treatment in the Neonates and ChildrenSurfactant Treatment in the Adult Patients; Inhaled Nitric Oxide (iNO); Aerosolized Prostacyclin; Non-conventional Approaches (Cell and/or Gene Therapy); Cell-Based Approaches; Gene-Based Therapy; Cell-Delivered Gene Therapy; Conclusion; References; Editor Contact Information; Index In this book, authors review the current knowledge on acute lung injury (ALI). ALI/acute respiratory distress syndrome (ARDS) is characterized by diffuse alveolar damage, alveolar capillary leakage, lung edema, neutrophil-derived inflammation, and surfactant dysfunction. These changes lead to clinical manifestations of decreased lung compliance, severe hypoxemia, and bilateral pulmonary infiltrates. In the first chapter the authors describe how two different models of multi-causality (intuitively appealing threshold model and abstract sufficient cause model), both of which are commonly used in Lungs / Wounds and injuries / Congresses Respiratory distress syndrome, Adult / Congresses Respiratory intensive care / Congresses HEALTH & FITNESS / Diseases / General bisacsh MEDICAL / Clinical Medicine bisacsh MEDICAL / Diseases bisacsh MEDICAL / Evidence-Based Medicine bisacsh MEDICAL / Internal Medicine bisacsh Lungs / Wounds and injuries fast Respiratory distress syndrome, Adult fast Respiratory intensive care fast Evidenz-basierte Medizin Innere Medizin Medizin Respiratory distress syndrome, Adult Congresses Respiratory intensive care Congresses Lungs Wounds and injuries Congresses (DE-588)1071861417 Konferenzschrift gnd-content Erscheint auch als Druck-Ausgabe Mokrá, Daniela Acute lung injury : epidemiology, health effects and therapeutic treatment strategies New York, New York : Nova Science Publishers, Inc., ©2014 ix, 86 pages Pulmonary and Respiratory Diseases and Disorders 9781614704263 |
| spellingShingle | Mokra, Daniela Acute lung injury epidemiology, health effects and therapeutic treatment strategies ACUTE LUNG INJURY: EPIDEMIOLOGY, HEALTH EFFECTS AND THERAPEUTIC TREATMENT STRATEGIES; ACUTE LUNG INJURY: EPIDEMIOLOGY, HEALTH EFFECTS AND THERAPEUTIC TREATMENT STRATEGIES; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter 1: TRALI Not a Two Hit, But a Multi-Causal Model; Center for Clinical Transfusion Research, Sanquin Research, Leiden; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands; Abstract; Introduction; Threshold Models; A More General Threshold Model of Multi-Causality; The Sufficient Cause Model; Discussion ConclusionReferences; Chapter 2: Mechanisms and Prevention of Pulmonary Microvascular Hyperpermeability in Acute Lung Injury; Abstract; Introduction; Pulmonary Microvascular Hyperpermeability; in Acute Lung Injury; The Mechanisms of Pulmonary Microvascular Hyperpermeability in Acute Lung Injury; Macrophages; Neutrophils; Platelets; Cell Organelles; Small G Protein; Calcium; HMGB1; Cell Junctions; Nitric Oxide (NO) and Inducible Nitric Oxide Synthase (iNOS); Focal Adhesions (FAs) Complex and FA Kinase (FAK); Hyperoxia; Prospective Approach to Heal ALI; References Chapter 3: Pharmacological Therapies for Acute Respiratory Distress SyndromeAbstract; Introduction; Corticosteroids; Neutrophil Elastase Inhibitors; Anticoagulant Therapies; Conclusion; References; Chapter 4: Novel Trends in Pharmacotherapy of Acute Lung Injury and Acute Respiratory Distress Syndrome; ABSTRACT; Definition of ALI/ARDS; Pathophysiology of ALI/ARDS as a Rationale for the Treatment; Pharmacotherapy of ALI/ARDS; Types, Dosage and Delivery of Exogenous Surfactants; Effects of Surfactant Administration; Complications of Surfactant Administration Surfactant Treatment in the Neonates and ChildrenSurfactant Treatment in the Adult Patients; Inhaled Nitric Oxide (iNO); Aerosolized Prostacyclin; Non-conventional Approaches (Cell and/or Gene Therapy); Cell-Based Approaches; Gene-Based Therapy; Cell-Delivered Gene Therapy; Conclusion; References; Editor Contact Information; Index In this book, authors review the current knowledge on acute lung injury (ALI). ALI/acute respiratory distress syndrome (ARDS) is characterized by diffuse alveolar damage, alveolar capillary leakage, lung edema, neutrophil-derived inflammation, and surfactant dysfunction. These changes lead to clinical manifestations of decreased lung compliance, severe hypoxemia, and bilateral pulmonary infiltrates. In the first chapter the authors describe how two different models of multi-causality (intuitively appealing threshold model and abstract sufficient cause model), both of which are commonly used in Lungs / Wounds and injuries / Congresses Respiratory distress syndrome, Adult / Congresses Respiratory intensive care / Congresses HEALTH & FITNESS / Diseases / General bisacsh MEDICAL / Clinical Medicine bisacsh MEDICAL / Diseases bisacsh MEDICAL / Evidence-Based Medicine bisacsh MEDICAL / Internal Medicine bisacsh Lungs / Wounds and injuries fast Respiratory distress syndrome, Adult fast Respiratory intensive care fast Evidenz-basierte Medizin Innere Medizin Medizin Respiratory distress syndrome, Adult Congresses Respiratory intensive care Congresses Lungs Wounds and injuries Congresses |
| subject_GND | (DE-588)1071861417 |
| title | Acute lung injury epidemiology, health effects and therapeutic treatment strategies |
| title_auth | Acute lung injury epidemiology, health effects and therapeutic treatment strategies |
| title_exact_search | Acute lung injury epidemiology, health effects and therapeutic treatment strategies |
| title_full | Acute lung injury epidemiology, health effects and therapeutic treatment strategies Daniela Mokrá |
| title_fullStr | Acute lung injury epidemiology, health effects and therapeutic treatment strategies Daniela Mokrá |
| title_full_unstemmed | Acute lung injury epidemiology, health effects and therapeutic treatment strategies Daniela Mokrá |
| title_short | Acute lung injury |
| title_sort | acute lung injury epidemiology health effects and therapeutic treatment strategies |
| title_sub | epidemiology, health effects and therapeutic treatment strategies |
| topic | Lungs / Wounds and injuries / Congresses Respiratory distress syndrome, Adult / Congresses Respiratory intensive care / Congresses HEALTH & FITNESS / Diseases / General bisacsh MEDICAL / Clinical Medicine bisacsh MEDICAL / Diseases bisacsh MEDICAL / Evidence-Based Medicine bisacsh MEDICAL / Internal Medicine bisacsh Lungs / Wounds and injuries fast Respiratory distress syndrome, Adult fast Respiratory intensive care fast Evidenz-basierte Medizin Innere Medizin Medizin Respiratory distress syndrome, Adult Congresses Respiratory intensive care Congresses Lungs Wounds and injuries Congresses |
| topic_facet | Lungs / Wounds and injuries / Congresses Respiratory distress syndrome, Adult / Congresses Respiratory intensive care / Congresses HEALTH & FITNESS / Diseases / General MEDICAL / Clinical Medicine MEDICAL / Diseases MEDICAL / Evidence-Based Medicine MEDICAL / Internal Medicine Lungs / Wounds and injuries Respiratory distress syndrome, Adult Respiratory intensive care Evidenz-basierte Medizin Innere Medizin Medizin Respiratory distress syndrome, Adult Congresses Respiratory intensive care Congresses Lungs Wounds and injuries Congresses Konferenzschrift |
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