Horizons in neuroscience research, Volume 13:
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York
Nova Science
[2014]
|
| Schriftenreihe: | Horizons in Neuroscience Research
|
| Schlagworte: | |
| Beschreibung: | Print version record |
| Beschreibung: | 1 online resource |
| ISBN: | 9781629484273 162948427X |
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| 505 | 8 | |a In this book, the authors present current research in the study of the causes, treatment options and potential complications of cirrhosis. Topics discussed include optimal medical management of liver cirrhosis without liver transplant; cardiac dysfunction in end stage liver disease; bacterial infections in cirrhosis; asymmetric dimethylarginine (ADMA) and endothelial dysfunction in cirrhosis; surgical risk associated with cirrhosis; the physics of liver fibrosis and cirrhosis; endoscopic obliterative therapy with cyanoacrylate for gastric varices; and surgical resection of hepatocellular carci | |
| 505 | 8 | |a HORIZONS IN NEUROSCIENCE RESEARCH. VOLUME 13; HORIZONS IN NEUROSCIENCE RESEARCH. VOLUME 13; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter 1: Role of Injured Nerve-Derived COX2/PGE2/EP Signaling in the Genesis of Neuropathic Pain; Abstract; 1. Overview of the Role of Injured Nerve-Derived COX2/PGE2/EP Signaling in the Genesis of NeP; 2. Up-Regulation of COX2/PGE2/EP Signaling during the Development of NeP; 2.1. Up-regulation of COX2/PGE2 in Injured Nerves; 2.3. Transient Up-Regulation of COX2 in the Superficial Dorsal Horn Following Nerve Injury | |
| 505 | 8 | |a 2.4. Up-regulation of EP Receptors in Injured Nerves and DRG Neurons3. Involvement of COX2/PGE2/EP Signaling in the Genesis of NeP; 3.1. Intraplantar or Perineural Injection of the Non-Selective COX Inhibitor, the Selective COX2 Inhibitor or the Selective EP Receptor Antagonists Relieved NeP; 3.2. Systemic Administration of the Non-Selective COX Inhibitor or the Selective COX2 Inhibitor Relieved NeP; 3.3. Intrathecal Injection of the Non-Selective COX Inhibitor or the Selective COX2 Inhibitor Relieved NeP. | |
| 505 | 8 | |a 3.4. Effectiveness of Local Injection of EP1 and EP4 Receptor Antagonist in Relief of Nerve Injury-Elicited NeP4. Mechanisms Underlying the Contribution of Injured Nerve-Derived COX2/PGE2/EP Signaling to the Genesis of NeP; 4.1. Role of COX2/PGE2/EP Signaling in Facilitating the Synthesis of Pain Mediators by Invading Macrophages in injured Nerves; 4.1.1. COX2/PGE2/EP4 signaling stimulates the synthesis of cytokine IL-6 by invading macrophages in injured nerves; 4.1.2. COX2/PGE2/EP signaling stimulates the synthesis of pain-related peptide CGRP in injured nerves | |
| 505 | 8 | |a 4.1.3. COX2/PGE2/EP signaling likely stimulates the synthesis of other pain mediators in injured nerves4.2. Facilitating the Synthesis of Inflammatory and Pain Mediators by DRG Neurons; 4.2.1. COX2/PGE2/EP signaling in injured nerves contribute to the synthesis of pain-related peptides SP and CGRP in DRG neurons; 4.2.2. COX2/PGE2/EP4 signaling in injured nerves contributes to the de novo synthesis of pro-inflammatory cytokine IL-6 in DRG neurons; 4.2.3. COX2/PGE2/EP4 signaling in injured nerves contributes to the up-regulation of BDNF in injured medium and large size DRG neurons | |
| 505 | 8 | |a 4.2.4. COX2/PGE2/EP4 signaling in injured nerves contributes to the up-regulation of TRPV1 and P2X3 in DRG neurons following nerve injury5. Clinical Relevance; Conclusion; Acknowledgments; References; Chapter 2: Cannabinoid Receptor- and Metabotropic Glutamate Receptor-Mediated Signaling in Neural Circuits of the Main Olfactory Bulb; Abstract; The Endocannabinoid System; Juxtaglomerular Neurons in the Main Olfactory Bulb; Regulation of Periglomerular Cell Activity; through CB1R; Cannabinoids Regulate Activity of and Synaptic Transmission to External Tufted Cells | |
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| 700 | 1 | |a Villalba, Eugenio |4 edt | |
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Datensatz im Suchindex
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| bvnumber | BV044358034 |
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| contents | In this book, the authors present current research in the study of the causes, treatment options and potential complications of cirrhosis. Topics discussed include optimal medical management of liver cirrhosis without liver transplant; cardiac dysfunction in end stage liver disease; bacterial infections in cirrhosis; asymmetric dimethylarginine (ADMA) and endothelial dysfunction in cirrhosis; surgical risk associated with cirrhosis; the physics of liver fibrosis and cirrhosis; endoscopic obliterative therapy with cyanoacrylate for gastric varices; and surgical resection of hepatocellular carci HORIZONS IN NEUROSCIENCE RESEARCH. VOLUME 13; HORIZONS IN NEUROSCIENCE RESEARCH. VOLUME 13; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter 1: Role of Injured Nerve-Derived COX2/PGE2/EP Signaling in the Genesis of Neuropathic Pain; Abstract; 1. Overview of the Role of Injured Nerve-Derived COX2/PGE2/EP Signaling in the Genesis of NeP; 2. Up-Regulation of COX2/PGE2/EP Signaling during the Development of NeP; 2.1. Up-regulation of COX2/PGE2 in Injured Nerves; 2.3. Transient Up-Regulation of COX2 in the Superficial Dorsal Horn Following Nerve Injury 2.4. Up-regulation of EP Receptors in Injured Nerves and DRG Neurons3. Involvement of COX2/PGE2/EP Signaling in the Genesis of NeP; 3.1. Intraplantar or Perineural Injection of the Non-Selective COX Inhibitor, the Selective COX2 Inhibitor or the Selective EP Receptor Antagonists Relieved NeP; 3.2. Systemic Administration of the Non-Selective COX Inhibitor or the Selective COX2 Inhibitor Relieved NeP; 3.3. Intrathecal Injection of the Non-Selective COX Inhibitor or the Selective COX2 Inhibitor Relieved NeP. 3.4. Effectiveness of Local Injection of EP1 and EP4 Receptor Antagonist in Relief of Nerve Injury-Elicited NeP4. Mechanisms Underlying the Contribution of Injured Nerve-Derived COX2/PGE2/EP Signaling to the Genesis of NeP; 4.1. Role of COX2/PGE2/EP Signaling in Facilitating the Synthesis of Pain Mediators by Invading Macrophages in injured Nerves; 4.1.1. COX2/PGE2/EP4 signaling stimulates the synthesis of cytokine IL-6 by invading macrophages in injured nerves; 4.1.2. COX2/PGE2/EP signaling stimulates the synthesis of pain-related peptide CGRP in injured nerves 4.1.3. COX2/PGE2/EP signaling likely stimulates the synthesis of other pain mediators in injured nerves4.2. Facilitating the Synthesis of Inflammatory and Pain Mediators by DRG Neurons; 4.2.1. COX2/PGE2/EP signaling in injured nerves contribute to the synthesis of pain-related peptides SP and CGRP in DRG neurons; 4.2.2. COX2/PGE2/EP4 signaling in injured nerves contributes to the de novo synthesis of pro-inflammatory cytokine IL-6 in DRG neurons; 4.2.3. COX2/PGE2/EP4 signaling in injured nerves contributes to the up-regulation of BDNF in injured medium and large size DRG neurons 4.2.4. COX2/PGE2/EP4 signaling in injured nerves contributes to the up-regulation of TRPV1 and P2X3 in DRG neurons following nerve injury5. Clinical Relevance; Conclusion; Acknowledgments; References; Chapter 2: Cannabinoid Receptor- and Metabotropic Glutamate Receptor-Mediated Signaling in Neural Circuits of the Main Olfactory Bulb; Abstract; The Endocannabinoid System; Juxtaglomerular Neurons in the Main Olfactory Bulb; Regulation of Periglomerular Cell Activity; through CB1R; Cannabinoids Regulate Activity of and Synaptic Transmission to External Tufted Cells |
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| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:50:42Z |
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| language | English |
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| spelling | Horizons in neuroscience research, Volume 13 Andres Costa and Eugenio Villalba, editors New York Nova Science [2014] 1 online resource txt rdacontent c rdamedia cr rdacarrier Horizons in Neuroscience Research Print version record In this book, the authors present current research in the study of the causes, treatment options and potential complications of cirrhosis. Topics discussed include optimal medical management of liver cirrhosis without liver transplant; cardiac dysfunction in end stage liver disease; bacterial infections in cirrhosis; asymmetric dimethylarginine (ADMA) and endothelial dysfunction in cirrhosis; surgical risk associated with cirrhosis; the physics of liver fibrosis and cirrhosis; endoscopic obliterative therapy with cyanoacrylate for gastric varices; and surgical resection of hepatocellular carci HORIZONS IN NEUROSCIENCE RESEARCH. VOLUME 13; HORIZONS IN NEUROSCIENCE RESEARCH. VOLUME 13; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter 1: Role of Injured Nerve-Derived COX2/PGE2/EP Signaling in the Genesis of Neuropathic Pain; Abstract; 1. Overview of the Role of Injured Nerve-Derived COX2/PGE2/EP Signaling in the Genesis of NeP; 2. Up-Regulation of COX2/PGE2/EP Signaling during the Development of NeP; 2.1. Up-regulation of COX2/PGE2 in Injured Nerves; 2.3. Transient Up-Regulation of COX2 in the Superficial Dorsal Horn Following Nerve Injury 2.4. Up-regulation of EP Receptors in Injured Nerves and DRG Neurons3. Involvement of COX2/PGE2/EP Signaling in the Genesis of NeP; 3.1. Intraplantar or Perineural Injection of the Non-Selective COX Inhibitor, the Selective COX2 Inhibitor or the Selective EP Receptor Antagonists Relieved NeP; 3.2. Systemic Administration of the Non-Selective COX Inhibitor or the Selective COX2 Inhibitor Relieved NeP; 3.3. Intrathecal Injection of the Non-Selective COX Inhibitor or the Selective COX2 Inhibitor Relieved NeP. 3.4. Effectiveness of Local Injection of EP1 and EP4 Receptor Antagonist in Relief of Nerve Injury-Elicited NeP4. Mechanisms Underlying the Contribution of Injured Nerve-Derived COX2/PGE2/EP Signaling to the Genesis of NeP; 4.1. Role of COX2/PGE2/EP Signaling in Facilitating the Synthesis of Pain Mediators by Invading Macrophages in injured Nerves; 4.1.1. COX2/PGE2/EP4 signaling stimulates the synthesis of cytokine IL-6 by invading macrophages in injured nerves; 4.1.2. COX2/PGE2/EP signaling stimulates the synthesis of pain-related peptide CGRP in injured nerves 4.1.3. COX2/PGE2/EP signaling likely stimulates the synthesis of other pain mediators in injured nerves4.2. Facilitating the Synthesis of Inflammatory and Pain Mediators by DRG Neurons; 4.2.1. COX2/PGE2/EP signaling in injured nerves contribute to the synthesis of pain-related peptides SP and CGRP in DRG neurons; 4.2.2. COX2/PGE2/EP4 signaling in injured nerves contributes to the de novo synthesis of pro-inflammatory cytokine IL-6 in DRG neurons; 4.2.3. COX2/PGE2/EP4 signaling in injured nerves contributes to the up-regulation of BDNF in injured medium and large size DRG neurons 4.2.4. COX2/PGE2/EP4 signaling in injured nerves contributes to the up-regulation of TRPV1 and P2X3 in DRG neurons following nerve injury5. Clinical Relevance; Conclusion; Acknowledgments; References; Chapter 2: Cannabinoid Receptor- and Metabotropic Glutamate Receptor-Mediated Signaling in Neural Circuits of the Main Olfactory Bulb; Abstract; The Endocannabinoid System; Juxtaglomerular Neurons in the Main Olfactory Bulb; Regulation of Periglomerular Cell Activity; through CB1R; Cannabinoids Regulate Activity of and Synaptic Transmission to External Tufted Cells Neurosciences / Periodicals Neurosciences MEDICAL / Physiology bisacsh SCIENCE / Life Sciences / Human Anatomy & Physiology bisacsh Nervous system / Diseases fast Neurosciences fast Medizin Neurosciences Nervous system Diseases Costa, Andres edt Villalba, Eugenio edt Erscheint auch als Druck-Ausgabe Horizons in neuroscience research 1626189641 |
| spellingShingle | Horizons in neuroscience research, Volume 13 In this book, the authors present current research in the study of the causes, treatment options and potential complications of cirrhosis. Topics discussed include optimal medical management of liver cirrhosis without liver transplant; cardiac dysfunction in end stage liver disease; bacterial infections in cirrhosis; asymmetric dimethylarginine (ADMA) and endothelial dysfunction in cirrhosis; surgical risk associated with cirrhosis; the physics of liver fibrosis and cirrhosis; endoscopic obliterative therapy with cyanoacrylate for gastric varices; and surgical resection of hepatocellular carci HORIZONS IN NEUROSCIENCE RESEARCH. VOLUME 13; HORIZONS IN NEUROSCIENCE RESEARCH. VOLUME 13; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter 1: Role of Injured Nerve-Derived COX2/PGE2/EP Signaling in the Genesis of Neuropathic Pain; Abstract; 1. Overview of the Role of Injured Nerve-Derived COX2/PGE2/EP Signaling in the Genesis of NeP; 2. Up-Regulation of COX2/PGE2/EP Signaling during the Development of NeP; 2.1. Up-regulation of COX2/PGE2 in Injured Nerves; 2.3. Transient Up-Regulation of COX2 in the Superficial Dorsal Horn Following Nerve Injury 2.4. Up-regulation of EP Receptors in Injured Nerves and DRG Neurons3. Involvement of COX2/PGE2/EP Signaling in the Genesis of NeP; 3.1. Intraplantar or Perineural Injection of the Non-Selective COX Inhibitor, the Selective COX2 Inhibitor or the Selective EP Receptor Antagonists Relieved NeP; 3.2. Systemic Administration of the Non-Selective COX Inhibitor or the Selective COX2 Inhibitor Relieved NeP; 3.3. Intrathecal Injection of the Non-Selective COX Inhibitor or the Selective COX2 Inhibitor Relieved NeP. 3.4. Effectiveness of Local Injection of EP1 and EP4 Receptor Antagonist in Relief of Nerve Injury-Elicited NeP4. Mechanisms Underlying the Contribution of Injured Nerve-Derived COX2/PGE2/EP Signaling to the Genesis of NeP; 4.1. Role of COX2/PGE2/EP Signaling in Facilitating the Synthesis of Pain Mediators by Invading Macrophages in injured Nerves; 4.1.1. COX2/PGE2/EP4 signaling stimulates the synthesis of cytokine IL-6 by invading macrophages in injured nerves; 4.1.2. COX2/PGE2/EP signaling stimulates the synthesis of pain-related peptide CGRP in injured nerves 4.1.3. COX2/PGE2/EP signaling likely stimulates the synthesis of other pain mediators in injured nerves4.2. Facilitating the Synthesis of Inflammatory and Pain Mediators by DRG Neurons; 4.2.1. COX2/PGE2/EP signaling in injured nerves contribute to the synthesis of pain-related peptides SP and CGRP in DRG neurons; 4.2.2. COX2/PGE2/EP4 signaling in injured nerves contributes to the de novo synthesis of pro-inflammatory cytokine IL-6 in DRG neurons; 4.2.3. COX2/PGE2/EP4 signaling in injured nerves contributes to the up-regulation of BDNF in injured medium and large size DRG neurons 4.2.4. COX2/PGE2/EP4 signaling in injured nerves contributes to the up-regulation of TRPV1 and P2X3 in DRG neurons following nerve injury5. Clinical Relevance; Conclusion; Acknowledgments; References; Chapter 2: Cannabinoid Receptor- and Metabotropic Glutamate Receptor-Mediated Signaling in Neural Circuits of the Main Olfactory Bulb; Abstract; The Endocannabinoid System; Juxtaglomerular Neurons in the Main Olfactory Bulb; Regulation of Periglomerular Cell Activity; through CB1R; Cannabinoids Regulate Activity of and Synaptic Transmission to External Tufted Cells Neurosciences / Periodicals Neurosciences MEDICAL / Physiology bisacsh SCIENCE / Life Sciences / Human Anatomy & Physiology bisacsh Nervous system / Diseases fast Neurosciences fast Medizin Neurosciences Nervous system Diseases |
| title | Horizons in neuroscience research, Volume 13 |
| title_auth | Horizons in neuroscience research, Volume 13 |
| title_exact_search | Horizons in neuroscience research, Volume 13 |
| title_full | Horizons in neuroscience research, Volume 13 Andres Costa and Eugenio Villalba, editors |
| title_fullStr | Horizons in neuroscience research, Volume 13 Andres Costa and Eugenio Villalba, editors |
| title_full_unstemmed | Horizons in neuroscience research, Volume 13 Andres Costa and Eugenio Villalba, editors |
| title_short | Horizons in neuroscience research, Volume 13 |
| title_sort | horizons in neuroscience research volume 13 |
| topic | Neurosciences / Periodicals Neurosciences MEDICAL / Physiology bisacsh SCIENCE / Life Sciences / Human Anatomy & Physiology bisacsh Nervous system / Diseases fast Neurosciences fast Medizin Neurosciences Nervous system Diseases |
| topic_facet | Neurosciences / Periodicals Neurosciences MEDICAL / Physiology SCIENCE / Life Sciences / Human Anatomy & Physiology Nervous system / Diseases Medizin Neurosciences Nervous system Diseases |
| work_keys_str_mv | AT costaandres horizonsinneuroscienceresearchvolume13 AT villalbaeugenio horizonsinneuroscienceresearchvolume13 |