Verfügbarkeit: Poly(ADP-Ribose) Polymerase

Poly(ADP-Ribose) Polymerase: methods and protocols

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Weitere Verfasser:	Tulin, Alexei V. (HerausgeberIn)
Format:	Buch
Sprache:	English
Veröffentlicht:	New York, NY Humana Press [2017]
Ausgabe:	Second edition
Schriftenreihe:	Methods in molecular biology 1608
Schlagworte:	Methode NAD-ADP-Ribosyltransferase Aufsatzsammlung
Online-Zugang:	Inhaltstext Inhaltsverzeichnis
Beschreibung:	XV, 528 Seiten Illustrationen, Diagramme
ISBN:	9781493969920 1493969927

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MARC


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Datensatz im Suchindex

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adam_text	Titel: Poly(ADP-Ribose) Polymerase Autor: Tulin, Alexei V Jahr: 2017 Contents Preface. v Contributors. xi Part I Detection and Quantification of pADPr 1 Quantitation of Poly(ADP-Ribose) by Isotope Dilution Mass Spectrometry. 3 Tabea Zubel, Rita Martello, Alexander Biirkle, and Aswin Mangerich 2 Quantification of PARP Activity in Human Tissues: Ex Vivo Assays in Blood Cells and Immunohistochemistry in Human Biopsies. 19 Eszter M. Horvath, Zsuzsanna K. ZsengelUr, and Csaba Szabo 3 Detecting and Quantifying pADPr In Vivo. 27 Ti-Chen Lai, Rajesb K. Aneja, Margaret A, Satcbell, and Robert S.B. Clark 4 Compartment-Specific Poly-ADP-Ribose Formation as a Biosensor for Subcellular NAD Pools. 45 Magali R. VanLinden, Marc Niere, Andrey A. Nikiforov, Matbias Ziegler, and Christian Dblle 5 Cell Cycle Resolved Measurements of Poly(ADP-Ribose) Formation and DNA Damage Signaling by Quantitative Image-Based Cytometry. 57 Jone Michelena and Matthias Altmeyer Part II Identification of Protein Targets 6 Detecting Protein ADP-Ribosylation Using a Clickable Aminooxy Probe . 71 Rory K. Morgan and Michael S. Cohen 7 ADP-Ribosylated Peptide Enrichment and Site Identification: The Phosphodiesterase-Based Method. 79 Casey M. Daniels, Shao-En Ong, and Anthony K.L. Leung 8 Using Clickable NAD* Analogs to Label Substrate Proteins of PARPs. 95 Lu Zhang and Hening Lin 9 Identification of Protein Substrates of Specific PARP Enzymes Using Analog- Sensitive PARP Mutants and a "Clickable" NAD* Analog. Ill Bryan A. Gibson and W. Lee Kraus 10 Identification of ADP-Ribose Acceptor Sites on In Vitro Modified Proteins by Liquid Chromatography-Tandem Mass Spectrometry. 137 Mario Leutert, Vera Bilan, Peter Gehrig, and Michael O. Hottiger Vii viii Contents 11 Proteome-Wide Identification of In Vivo ADP-Ribose Acceptor Sites by Liquid Chromatography-Tandem Mass Spectrometry. 149 Sara C. Larsen, Mario Leutert, Vera Bilan, Rita Martello, Stephanie Jungmichel, Clifford Young, Michael O. Hottiger, and Michael L. Nielsen Part III Functional Analysis 12 Poly(ADP-Ribose)-Dependent Chromatin Remodeling in DNA Repair. 165 ThSo Lebeaupin, Rebecca Smith, Sebastien Huet, and Gyula Timinszky 13 Methods to Assess the Role of Poly(ADP-Ribose) Polymerases in Regulating Mitochondrial Oxidation. 185 Edit Mikd, Tiinde Kovdcs, Tamds Fodor, and Pdter Bai 14 Approaches for Investigating Translational Regulation Controlled by PARP1: Biotin-Based UV Cross-Linking and Luciferase Reporter Assay . 201 Yingbiao Ji 15 Methodology to Identify Poly-ADP-Ribose Polymerase 1 (PARPl)-mRNA Targets by PAR-CLiP. 211 Manana Mekishvili, Elena Matveeva, and Yvonne Fondufe-Mittendorf Part IV Regulation of PARP-1 and Its Partners 16 Biochemical and Biophysical Methods for Analysis of Poly(ADP-Ribose) Polymerase 1 and Its Interactions with Chromatin. 231 Maggie H. ChassS, Uma M. Muthurajan, Nicholas J. Clark, Michael A. Kramer, Srinivas Chakravarthy, Thomas Irving, and Karolin Luger 17 PARP-1 Interaction with and Activation by Histones and Nucleosomes. 255 Colin Thomas, Elena Kotova, and Alexei V. Tulin Part V Designing and Testing PARP-1 Inhibitors 18 Strategies Employed for the Development of PARP Inhibitors. 271 Stacie Canan, Karen Maegley, and Nicola J. Curtin 19 High-Throughput Colorimetric Assay for Identifying PARP-1 Inhibitors Using a Large Small-Molecule Collection. 299 Elena Kotova and Alexei V. Tulin 20 Testing PARP Inhibitors Using a Murine Xenograft Model. 313 Peter Makhov, Sei Naito, and Vladimir M. Kolenko 21 In Vitro Long-Term Proliferation Assays to Study Antiproliferative Effects of PARP Inhibitors on Cancer Cells. 321 Heike Keilhack and Paul Chang 22 Use of Inosine Monophosphate Dehydrogenase Activity Assay to Determine the Specificity of PARJP-1 Inhibitors. 337 Sajitha Anthony, Jeffrey R. Peterson, and Yingbiao Ji Contents ix 23 The Use of PARP Inhibitors in Cancer Therapy: Use as Adjuvant with Chemotherapy or Radiotherapy, Use as a Single Agent in Susceptible Patients, and Techniques Used to Identify Susceptible Patients. 343 Sydney Shall, Terry Gaymes, Farzin Farzaneh, Nicola J. Curtin, and Ghulam J. Mufti Part VI Targeting the Understudied Components of pADPr Pathway 24 Purification of Recombinant Human PARP-3. 373 Jean-Christophe Ami, Barbara Camuzeaux, Franfoise Dantzer, and Valerie Schreiber 25 Purification of Recombinant Human PARG and Activity Assays. 395 Jean-Christophe Ami, Â£lia Hiberli, Barbara Camuzeaux, Franfoise Dantzer, and Valirie Schreiber 26 Studying Catabolism of Protein ADP-Ribosylation. 415 Luca Palazzo, Dominic I. James, Ian D. Waddell, and Ivan Ahel 27 Purification of DNA Damage-Dependent PARPs from E. coli for Structural and Biochemical Analysis. 431 Marie-France Langelier, Jamin D. Steffen, Amanda A. Riccio, Michael McCauley, and John M. Pascal 28 Identifying and Validating Tankyrase Binders and Substrates: A Candidate Approach. 445 Katie Pollock, Michael Ranes, Ian Collins, and Sebastian Guettler 29 Computational and Experimental Studies of ADP-Ribosylation. 475 Robert G. Hammond, Xuan Tan, Matthew Chan, Anupam Goel, and Margaret A. Johnson Index 515
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spelling	Poly(ADP-Ribose) Polymerase methods and protocols edited by Alexei V. Tulin Second edition New York, NY Humana Press [2017] XV, 528 Seiten Illustrationen, Diagramme txt rdacontent n rdamedia nc rdacarrier Methods in molecular biology 1608 Springer protocols Methode (DE-588)4038971-6 gnd rswk-swf NAD-ADP-Ribosyltransferase (DE-588)4313462-2 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content NAD-ADP-Ribosyltransferase (DE-588)4313462-2 s Methode (DE-588)4038971-6 s 2\p DE-604 Tulin, Alexei V. edt Erscheint auch als eBook 978-1-4939-6993-7 Methods in molecular biology 1608 (DE-604)BV035362695 1608 X:MVB text/html http://deposit.dnb.de/cgi-bin/dokserv?id=317e26e1c34045b0abdccac8c5cbb3f8&prov=M&dok_var=1&dok_ext=htm Inhaltstext HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029752328&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk
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title	Poly(ADP-Ribose) Polymerase methods and protocols
title_auth	Poly(ADP-Ribose) Polymerase methods and protocols
title_exact_search	Poly(ADP-Ribose) Polymerase methods and protocols
title_full	Poly(ADP-Ribose) Polymerase methods and protocols edited by Alexei V. Tulin
title_fullStr	Poly(ADP-Ribose) Polymerase methods and protocols edited by Alexei V. Tulin
title_full_unstemmed	Poly(ADP-Ribose) Polymerase methods and protocols edited by Alexei V. Tulin
title_short	Poly(ADP-Ribose) Polymerase
title_sort	poly adp ribose polymerase methods and protocols
title_sub	methods and protocols
topic	Methode (DE-588)4038971-6 gnd NAD-ADP-Ribosyltransferase (DE-588)4313462-2 gnd
topic_facet	Methode NAD-ADP-Ribosyltransferase Aufsatzsammlung
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