Immunity: the evolution of an idea
" Senior scholar Alfred Tauber argues in this bold account that common approaches to the study of immunology are inherently flawed in its strict dichotomy of the self and non-self, or external invaders. The relationship between what is self and what is non-self is in reality a complex, dymanic,...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Oxford University Press
[2017]
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Zusammenfassung: | " Senior scholar Alfred Tauber argues in this bold account that common approaches to the study of immunology are inherently flawed in its strict dichotomy of the self and non-self, or external invaders. The relationship between what is self and what is non-self is in reality a complex, dymanic, relational one. Autonomous agents are constantly in the midst of dialectical exchanges in which immunity mediates both noxious and benign encounters. Namely: rather than serving to defend an independent entity, immunity participates in an eco-system. Contemporary transplantation biology and autoimmunity have demonstrated phenomena that upset rigid adherence to the self/non-self dichotomy. Placing tolerant immune mechanisms within a broad ecological context has highlighted the balance of co-operative and competitive relationships in which immunity functions. By understanding immunity this way, as a 'symbiotic turn,' we come to see that immune reactivity (rejection or tolerance) is a second-order response to the cognitive functions of the immune system. Organisms have a complex capacity to respond to environment, and, through Tauber's insignts, we appreciate them more fully when we grasp the flexibility of the borders of organisms. After first providing an overview of the history of immunology, and explaining why the dominant understanding of it is incomplete and limiting, Tauber argues for this new approach to immunology and explains how it will usher in a new biology in which symbiosis is the rule, not the exception. "... "Immunity mediates both defensive and cooperative relations with the environment. Therefore, the traditional focus on host defense misconstrues the full spectrum of immune activities. An alternate model based on immune balance highlights the information processing of immune perception that precedes discriminatory decisions ... to reject, assimilate, or ignore the identified object"... |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | xx, 303 Seiten |
| ISBN: | 9780190651244 |
Internformat
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV044287757 | ||
| 003 | DE-604 | ||
| 005 | 20180314 | ||
| 007 | t | ||
| 008 | 170427s2017 xxu |||| 00||| eng d | ||
| 010 | |a 016024105 | ||
| 020 | |a 9780190651244 |9 978-0-19-065124-4 | ||
| 035 | |a (OCoLC)983478552 | ||
| 035 | |a (DE-599)BVBBV044287757 | ||
| 040 | |a DE-604 |b ger |e rda | ||
| 041 | 0 | |a eng | |
| 044 | |a xxu |c US | ||
| 049 | |a DE-12 |a DE-19 |a DE-578 |a DE-11 | ||
| 050 | 0 | |a QR181 | |
| 082 | 0 | |a 616.07/9 |2 23 | |
| 084 | |a WB 4000 |0 (DE-625)147978: |2 rvk | ||
| 084 | |a WF 9000 |0 (DE-625)148448: |2 rvk | ||
| 100 | 1 | |a Tauber, Alfred I. |d 1947- |e Verfasser |0 (DE-588)101501786X |4 aut | |
| 245 | 1 | 0 | |a Immunity |b the evolution of an idea |c Alfred I. Tauber |
| 264 | 1 | |a New York, NY |b Oxford University Press |c [2017] | |
| 264 | 4 | |c © 2017 | |
| 300 | |a xx, 303 Seiten | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 500 | |a Includes bibliographical references and index | ||
| 520 | |a " Senior scholar Alfred Tauber argues in this bold account that common approaches to the study of immunology are inherently flawed in its strict dichotomy of the self and non-self, or external invaders. The relationship between what is self and what is non-self is in reality a complex, dymanic, relational one. Autonomous agents are constantly in the midst of dialectical exchanges in which immunity mediates both noxious and benign encounters. Namely: rather than serving to defend an independent entity, immunity participates in an eco-system. Contemporary transplantation biology and autoimmunity have demonstrated phenomena that upset rigid adherence to the self/non-self dichotomy. Placing tolerant immune mechanisms within a broad ecological context has highlighted the balance of co-operative and competitive relationships in which immunity functions. By understanding immunity this way, as a 'symbiotic turn,' we come to see that immune reactivity (rejection or tolerance) is a second-order response to the cognitive functions of the immune system. Organisms have a complex capacity to respond to environment, and, through Tauber's insignts, we appreciate them more fully when we grasp the flexibility of the borders of organisms. After first providing an overview of the history of immunology, and explaining why the dominant understanding of it is incomplete and limiting, Tauber argues for this new approach to immunology and explains how it will usher in a new biology in which symbiosis is the rule, not the exception. "... | ||
| 520 | |a "Immunity mediates both defensive and cooperative relations with the environment. Therefore, the traditional focus on host defense misconstrues the full spectrum of immune activities. An alternate model based on immune balance highlights the information processing of immune perception that precedes discriminatory decisions ... to reject, assimilate, or ignore the identified object"... | ||
| 648 | 7 | |a Geschichte |2 gnd |9 rswk-swf | |
| 650 | 7 | |a SCIENCE / Philosophy & Social Aspects |2 bisacsh | |
| 650 | 7 | |a MEDICAL / Immunology |2 bisacsh | |
| 650 | 4 | |a Medizin | |
| 650 | 4 | |a Philosophie | |
| 650 | 4 | |a Immunology |x Philosophy | |
| 650 | 4 | |a SCIENCE / Philosophy & Social Aspects | |
| 650 | 4 | |a MEDICAL / Immunology | |
| 650 | 0 | 7 | |a Philosophie |0 (DE-588)4045791-6 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Immunität |g Medizin |0 (DE-588)4120476-1 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Immunisierung |0 (DE-588)4161380-6 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Immunität |g Medizin |0 (DE-588)4120476-1 |D s |
| 689 | 0 | 1 | |a Immunisierung |0 (DE-588)4161380-6 |D s |
| 689 | 0 | 2 | |a Philosophie |0 (DE-588)4045791-6 |D s |
| 689 | 0 | 3 | |a Geschichte |A z |
| 689 | 0 | |5 DE-604 | |
| 776 | 0 | 8 | |i Erscheint auch als |n Online-Ausgabe, ebook |z 978-0-19-065126-8 |
| 776 | 0 | 8 | |i Erscheint auch als |n Online-Ausgabe, onlince resource |z 978-0-19-065127-5 |
| 856 | 4 | 2 | |m LoC Fremddatenuebernahme |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029691934&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-029691934 | ||
| 942 | 1 | 1 | |c 001.09 |e 22/bsb |
| 942 | 1 | 1 | |c 610.9 |e 22/bsb |
Datensatz im Suchindex
| _version_ | 1804177482923900928 |
|---|---|
| adam_text | IMMUNITY
/ TAUBER, ALFRED I.
: 2017
TABLE OF CONTENTS / INHALTSVERZEICHNIS
PREFACE
ACKNOWLEDGEMENTS
INTRODUCTION
CHAPTER 1: A HISTORY OF THE IMMUNE SELF
CHAPTER 2: WHITHER IMMUNE IDENTITY?
CHAPTER 3: INDIVIDUALITY REVISED
CHAPTER 4: IMMUNE COGNITION
CHAPTER 5: ECO-IMMUNOLOGY
CHAPTER 6: A NEW BIOLOGY?
EPILOGUE
ENDNOTES
REFERENCES.650
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
| any_adam_object | 1 |
| author | Tauber, Alfred I. 1947- |
| author_GND | (DE-588)101501786X |
| author_facet | Tauber, Alfred I. 1947- |
| author_role | aut |
| author_sort | Tauber, Alfred I. 1947- |
| author_variant | a i t ai ait |
| building | Verbundindex |
| bvnumber | BV044287757 |
| callnumber-first | Q - Science |
| callnumber-label | QR181 |
| callnumber-raw | QR181 |
| callnumber-search | QR181 |
| callnumber-sort | QR 3181 |
| callnumber-subject | QR - Microbiology |
| classification_rvk | WB 4000 WF 9000 |
| ctrlnum | (OCoLC)983478552 (DE-599)BVBBV044287757 |
| dewey-full | 616.07/9 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.07/9 |
| dewey-search | 616.07/9 |
| dewey-sort | 3616.07 19 |
| dewey-tens | 610 - Medicine and health |
| discipline | Biologie Medizin |
| era | Geschichte gnd |
| era_facet | Geschichte |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>04223nam a2200625 c 4500</leader><controlfield tag="001">BV044287757</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20180314 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">170427s2017 xxu |||| 00||| eng d</controlfield><datafield tag="010" ind1=" " ind2=" "><subfield code="a">016024105</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9780190651244</subfield><subfield code="9">978-0-19-065124-4</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)983478552</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV044287757</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="044" ind1=" " ind2=" "><subfield code="a">xxu</subfield><subfield code="c">US</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-12</subfield><subfield code="a">DE-19</subfield><subfield code="a">DE-578</subfield><subfield code="a">DE-11</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">QR181</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">616.07/9</subfield><subfield code="2">23</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WB 4000</subfield><subfield code="0">(DE-625)147978:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WF 9000</subfield><subfield code="0">(DE-625)148448:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Tauber, Alfred I.</subfield><subfield code="d">1947-</subfield><subfield code="e">Verfasser</subfield><subfield code="0">(DE-588)101501786X</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Immunity</subfield><subfield code="b">the evolution of an idea</subfield><subfield code="c">Alfred I. Tauber</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">New York, NY</subfield><subfield code="b">Oxford University Press</subfield><subfield code="c">[2017]</subfield></datafield><datafield tag="264" ind1=" " ind2="4"><subfield code="c">© 2017</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">xx, 303 Seiten</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Includes bibliographical references and index</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">" Senior scholar Alfred Tauber argues in this bold account that common approaches to the study of immunology are inherently flawed in its strict dichotomy of the self and non-self, or external invaders. The relationship between what is self and what is non-self is in reality a complex, dymanic, relational one. Autonomous agents are constantly in the midst of dialectical exchanges in which immunity mediates both noxious and benign encounters. Namely: rather than serving to defend an independent entity, immunity participates in an eco-system. Contemporary transplantation biology and autoimmunity have demonstrated phenomena that upset rigid adherence to the self/non-self dichotomy. Placing tolerant immune mechanisms within a broad ecological context has highlighted the balance of co-operative and competitive relationships in which immunity functions. By understanding immunity this way, as a 'symbiotic turn,' we come to see that immune reactivity (rejection or tolerance) is a second-order response to the cognitive functions of the immune system. Organisms have a complex capacity to respond to environment, and, through Tauber's insignts, we appreciate them more fully when we grasp the flexibility of the borders of organisms. After first providing an overview of the history of immunology, and explaining why the dominant understanding of it is incomplete and limiting, Tauber argues for this new approach to immunology and explains how it will usher in a new biology in which symbiosis is the rule, not the exception. "...</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">"Immunity mediates both defensive and cooperative relations with the environment. Therefore, the traditional focus on host defense misconstrues the full spectrum of immune activities. An alternate model based on immune balance highlights the information processing of immune perception that precedes discriminatory decisions ... to reject, assimilate, or ignore the identified object"...</subfield></datafield><datafield tag="648" ind1=" " ind2="7"><subfield code="a">Geschichte</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">SCIENCE / Philosophy & Social Aspects</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">MEDICAL / Immunology</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Medizin</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Philosophie</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Immunology</subfield><subfield code="x">Philosophy</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">SCIENCE / Philosophy & Social Aspects</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">MEDICAL / Immunology</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Philosophie</subfield><subfield code="0">(DE-588)4045791-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Immunität</subfield><subfield code="g">Medizin</subfield><subfield code="0">(DE-588)4120476-1</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Immunisierung</subfield><subfield code="0">(DE-588)4161380-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Immunität</subfield><subfield code="g">Medizin</subfield><subfield code="0">(DE-588)4120476-1</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Immunisierung</subfield><subfield code="0">(DE-588)4161380-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="2"><subfield code="a">Philosophie</subfield><subfield code="0">(DE-588)4045791-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="3"><subfield code="a">Geschichte</subfield><subfield code="A">z</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Online-Ausgabe, ebook</subfield><subfield code="z">978-0-19-065126-8</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Online-Ausgabe, onlince resource</subfield><subfield code="z">978-0-19-065127-5</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">LoC Fremddatenuebernahme</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029691934&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-029691934</subfield></datafield><datafield tag="942" ind1="1" ind2="1"><subfield code="c">001.09</subfield><subfield code="e">22/bsb</subfield></datafield><datafield tag="942" ind1="1" ind2="1"><subfield code="c">610.9</subfield><subfield code="e">22/bsb</subfield></datafield></record></collection> |
| id | DE-604.BV044287757 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:48:47Z |
| institution | BVB |
| isbn | 9780190651244 |
| language | English |
| lccn | 016024105 |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-029691934 |
| oclc_num | 983478552 |
| open_access_boolean | |
| owner | DE-12 DE-19 DE-BY-UBM DE-578 DE-11 |
| owner_facet | DE-12 DE-19 DE-BY-UBM DE-578 DE-11 |
| physical | xx, 303 Seiten |
| publishDate | 2017 |
| publishDateSearch | 2017 |
| publishDateSort | 2017 |
| publisher | Oxford University Press |
| record_format | marc |
| spelling | Tauber, Alfred I. 1947- Verfasser (DE-588)101501786X aut Immunity the evolution of an idea Alfred I. Tauber New York, NY Oxford University Press [2017] © 2017 xx, 303 Seiten txt rdacontent n rdamedia nc rdacarrier Includes bibliographical references and index " Senior scholar Alfred Tauber argues in this bold account that common approaches to the study of immunology are inherently flawed in its strict dichotomy of the self and non-self, or external invaders. The relationship between what is self and what is non-self is in reality a complex, dymanic, relational one. Autonomous agents are constantly in the midst of dialectical exchanges in which immunity mediates both noxious and benign encounters. Namely: rather than serving to defend an independent entity, immunity participates in an eco-system. Contemporary transplantation biology and autoimmunity have demonstrated phenomena that upset rigid adherence to the self/non-self dichotomy. Placing tolerant immune mechanisms within a broad ecological context has highlighted the balance of co-operative and competitive relationships in which immunity functions. By understanding immunity this way, as a 'symbiotic turn,' we come to see that immune reactivity (rejection or tolerance) is a second-order response to the cognitive functions of the immune system. Organisms have a complex capacity to respond to environment, and, through Tauber's insignts, we appreciate them more fully when we grasp the flexibility of the borders of organisms. After first providing an overview of the history of immunology, and explaining why the dominant understanding of it is incomplete and limiting, Tauber argues for this new approach to immunology and explains how it will usher in a new biology in which symbiosis is the rule, not the exception. "... "Immunity mediates both defensive and cooperative relations with the environment. Therefore, the traditional focus on host defense misconstrues the full spectrum of immune activities. An alternate model based on immune balance highlights the information processing of immune perception that precedes discriminatory decisions ... to reject, assimilate, or ignore the identified object"... Geschichte gnd rswk-swf SCIENCE / Philosophy & Social Aspects bisacsh MEDICAL / Immunology bisacsh Medizin Philosophie Immunology Philosophy SCIENCE / Philosophy & Social Aspects MEDICAL / Immunology Philosophie (DE-588)4045791-6 gnd rswk-swf Immunität Medizin (DE-588)4120476-1 gnd rswk-swf Immunisierung (DE-588)4161380-6 gnd rswk-swf Immunität Medizin (DE-588)4120476-1 s Immunisierung (DE-588)4161380-6 s Philosophie (DE-588)4045791-6 s Geschichte z DE-604 Erscheint auch als Online-Ausgabe, ebook 978-0-19-065126-8 Erscheint auch als Online-Ausgabe, onlince resource 978-0-19-065127-5 LoC Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029691934&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Tauber, Alfred I. 1947- Immunity the evolution of an idea SCIENCE / Philosophy & Social Aspects bisacsh MEDICAL / Immunology bisacsh Medizin Philosophie Immunology Philosophy SCIENCE / Philosophy & Social Aspects MEDICAL / Immunology Philosophie (DE-588)4045791-6 gnd Immunität Medizin (DE-588)4120476-1 gnd Immunisierung (DE-588)4161380-6 gnd |
| subject_GND | (DE-588)4045791-6 (DE-588)4120476-1 (DE-588)4161380-6 |
| title | Immunity the evolution of an idea |
| title_auth | Immunity the evolution of an idea |
| title_exact_search | Immunity the evolution of an idea |
| title_full | Immunity the evolution of an idea Alfred I. Tauber |
| title_fullStr | Immunity the evolution of an idea Alfred I. Tauber |
| title_full_unstemmed | Immunity the evolution of an idea Alfred I. Tauber |
| title_short | Immunity |
| title_sort | immunity the evolution of an idea |
| title_sub | the evolution of an idea |
| topic | SCIENCE / Philosophy & Social Aspects bisacsh MEDICAL / Immunology bisacsh Medizin Philosophie Immunology Philosophy SCIENCE / Philosophy & Social Aspects MEDICAL / Immunology Philosophie (DE-588)4045791-6 gnd Immunität Medizin (DE-588)4120476-1 gnd Immunisierung (DE-588)4161380-6 gnd |
| topic_facet | SCIENCE / Philosophy & Social Aspects MEDICAL / Immunology Medizin Philosophie Immunology Philosophy Immunität Medizin Immunisierung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=029691934&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT tauberalfredi immunitytheevolutionofanidea |