The vaccine race: how scientists used human cells to combat killer viruses
"The epic and controversial story of a major breakthrough in cell biology that led to the creation of some of the world's most important vaccines. Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, pop...
Gespeichert in:
1. Verfasser: | |
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Format: | Buch |
Sprache: | English |
Veröffentlicht: |
London ; Toronto ; Sydney ; Auckland ; Johannesburg
Doubleday
[2017]
|
Schlagworte: | |
Zusammenfassung: | "The epic and controversial story of a major breakthrough in cell biology that led to the creation of some of the world's most important vaccines. Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a devastating German measles epidemic, his colleague developed the vaccine that would one day wipe out homegrown rubella. The rubella vaccine and others made with those fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles and adenovirus. Meredith Wadman's masterful account recovers not only the science of this urgent race, but also the political roadblocks that nearly stopped the scientists. She describes the terrible dilemmas of pregnant women exposed to German measles and recounts testing on infants, prisoners, orphans, and the intellectually disabled, which was common in the era. These events take place at the dawn of the battle over using human fetal tissue in research, during the arrival of big commerce in campus labs, and as huge changes take place in the laws and practices governing who "owns" research cells and the profits made from biological inventions. It is also the story of yet one more unrecognized woman whose cells have been used to save countless lives. With another frightening virus imperiling pregnant women on the rise today, no medical story could have more human drama, impact, or urgency today than The Vaccine Race"... |
Beschreibung: | 448 Seiten |
ISBN: | 9780857522726 9780857522733 |
Internformat
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520 | |a "The epic and controversial story of a major breakthrough in cell biology that led to the creation of some of the world's most important vaccines. Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a devastating German measles epidemic, his colleague developed the vaccine that would one day wipe out homegrown rubella. The rubella vaccine and others made with those fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. | ||
520 | |a The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles and adenovirus. Meredith Wadman's masterful account recovers not only the science of this urgent race, but also the political roadblocks that nearly stopped the scientists. She describes the terrible dilemmas of pregnant women exposed to German measles and recounts testing on infants, prisoners, orphans, and the intellectually disabled, which was common in the era. These events take place at the dawn of the battle over using human fetal tissue in research, during the arrival of big commerce in campus labs, and as huge changes take place in the laws and practices governing who "owns" research cells and the profits made from biological inventions. It is also the story of yet one more unrecognized woman whose cells have been used to save countless lives. | ||
520 | |a With another frightening virus imperiling pregnant women on the rise today, no medical story could have more human drama, impact, or urgency today than The Vaccine Race"... | ||
650 | 4 | |a Rubella vaccines |x Research |z United States |x History |y 20th century | |
650 | 4 | |a Rubella vaccines |x Political aspects |z United States |x History |y 20th century | |
650 | 4 | |a Rubella |x Vaccination |x History |y 20th century | |
650 | 4 | |a MMR vaccine |x Research |z United States |x History |y 20th century | |
650 | 4 | |a Human experimentation in medicine |z United States |x History |y 20th century | |
650 | 4 | |a Human experimentation in medicine |x Political aspects |z United States |x History |y 20th century | |
650 | 4 | |a Measles-Mumps-Rubella Vaccine | |
650 | 4 | |a Human Experimentation | |
650 | 4 | |a History, 20th Century | |
650 | 0 | 7 | |a Impfstoff |0 (DE-588)4026655-2 |2 gnd |9 rswk-swf |
650 | 0 | 7 | |a Röteln |0 (DE-588)4178335-9 |2 gnd |9 rswk-swf |
651 | 4 | |a United States | |
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689 | 0 | |5 DE-604 | |
776 | 0 | 8 | |i Erscheint auch als |n Online-Ausgabe |a Wadman, Meredith, author |t Vaccine race |d New York, New York : Viking, [2016] |z 9780698177789 |
999 | |a oai:aleph.bib-bvb.de:BVB01-029616711 |
Datensatz im Suchindex
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any_adam_object | |
author | Wadman, Meredith |
author_GND | (DE-588)1126975109 |
author_facet | Wadman, Meredith |
author_role | aut |
author_sort | Wadman, Meredith |
author_variant | m w mw |
building | Verbundindex |
bvnumber | BV044210413 |
callnumber-first | R - Medicine |
callnumber-label | RA644 |
callnumber-raw | RA644.M5 |
callnumber-search | RA644.M5 |
callnumber-sort | RA 3644 M5 |
callnumber-subject | RA - Public Medicine |
classification_rvk | XD 3300 |
ctrlnum | (OCoLC)975239617 (DE-599)BVBBV044210413 |
dewey-full | 614.523 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 614 - Forensic medicine; incidence of disease |
dewey-raw | 614.523 |
dewey-search | 614.523 |
dewey-sort | 3614.523 |
dewey-tens | 610 - Medicine and health |
discipline | Medizin |
format | Book |
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spelling | Wadman, Meredith Verfasser (DE-588)1126975109 aut The vaccine race how scientists used human cells to combat killer viruses Meredith Wadman London ; Toronto ; Sydney ; Auckland ; Johannesburg Doubleday [2017] © 2017 448 Seiten txt rdacontent n rdamedia nc rdacarrier "The epic and controversial story of a major breakthrough in cell biology that led to the creation of some of the world's most important vaccines. Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a devastating German measles epidemic, his colleague developed the vaccine that would one day wipe out homegrown rubella. The rubella vaccine and others made with those fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles and adenovirus. Meredith Wadman's masterful account recovers not only the science of this urgent race, but also the political roadblocks that nearly stopped the scientists. She describes the terrible dilemmas of pregnant women exposed to German measles and recounts testing on infants, prisoners, orphans, and the intellectually disabled, which was common in the era. These events take place at the dawn of the battle over using human fetal tissue in research, during the arrival of big commerce in campus labs, and as huge changes take place in the laws and practices governing who "owns" research cells and the profits made from biological inventions. It is also the story of yet one more unrecognized woman whose cells have been used to save countless lives. With another frightening virus imperiling pregnant women on the rise today, no medical story could have more human drama, impact, or urgency today than The Vaccine Race"... Rubella vaccines Research United States History 20th century Rubella vaccines Political aspects United States History 20th century Rubella Vaccination History 20th century MMR vaccine Research United States History 20th century Human experimentation in medicine United States History 20th century Human experimentation in medicine Political aspects United States History 20th century Measles-Mumps-Rubella Vaccine Human Experimentation History, 20th Century Impfstoff (DE-588)4026655-2 gnd rswk-swf Röteln (DE-588)4178335-9 gnd rswk-swf United States Impfstoff (DE-588)4026655-2 s Röteln (DE-588)4178335-9 s DE-604 Erscheint auch als Online-Ausgabe Wadman, Meredith, author Vaccine race New York, New York : Viking, [2016] 9780698177789 |
spellingShingle | Wadman, Meredith The vaccine race how scientists used human cells to combat killer viruses Rubella vaccines Research United States History 20th century Rubella vaccines Political aspects United States History 20th century Rubella Vaccination History 20th century MMR vaccine Research United States History 20th century Human experimentation in medicine United States History 20th century Human experimentation in medicine Political aspects United States History 20th century Measles-Mumps-Rubella Vaccine Human Experimentation History, 20th Century Impfstoff (DE-588)4026655-2 gnd Röteln (DE-588)4178335-9 gnd |
subject_GND | (DE-588)4026655-2 (DE-588)4178335-9 |
title | The vaccine race how scientists used human cells to combat killer viruses |
title_auth | The vaccine race how scientists used human cells to combat killer viruses |
title_exact_search | The vaccine race how scientists used human cells to combat killer viruses |
title_full | The vaccine race how scientists used human cells to combat killer viruses Meredith Wadman |
title_fullStr | The vaccine race how scientists used human cells to combat killer viruses Meredith Wadman |
title_full_unstemmed | The vaccine race how scientists used human cells to combat killer viruses Meredith Wadman |
title_short | The vaccine race |
title_sort | the vaccine race how scientists used human cells to combat killer viruses |
title_sub | how scientists used human cells to combat killer viruses |
topic | Rubella vaccines Research United States History 20th century Rubella vaccines Political aspects United States History 20th century Rubella Vaccination History 20th century MMR vaccine Research United States History 20th century Human experimentation in medicine United States History 20th century Human experimentation in medicine Political aspects United States History 20th century Measles-Mumps-Rubella Vaccine Human Experimentation History, 20th Century Impfstoff (DE-588)4026655-2 gnd Röteln (DE-588)4178335-9 gnd |
topic_facet | Rubella vaccines Research United States History 20th century Rubella vaccines Political aspects United States History 20th century Rubella Vaccination History 20th century MMR vaccine Research United States History 20th century Human experimentation in medicine United States History 20th century Human experimentation in medicine Political aspects United States History 20th century Measles-Mumps-Rubella Vaccine Human Experimentation History, 20th Century Impfstoff Röteln United States |
work_keys_str_mv | AT wadmanmeredith thevaccineracehowscientistsusedhumancellstocombatkillerviruses |