Drug Delivery Strategies for Poorly Water-Soluble Drugs:
Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to patients. Consequently, the development of techniques and materials to overcome these hurdles is a major area of research in pharmaceutical companie...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Somerset
Wiley
2012
|
| Ausgabe: | 1st ed |
| Schriftenreihe: | Advances in Pharmaceutical Technology
|
| Schlagworte: | |
| Zusammenfassung: | Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to patients. Consequently, the development of techniques and materials to overcome these hurdles is a major area of research in pharmaceutical companies. Drug Delivery Strategies for Poorly Water-Soluble Drugs provides a comprehensive overview of currently used formulation strategies for hydrophobic drugs, including liposome formulation, cyclodextrin drug carriers, solid lipid nanoparticles, polymeric drug encapsulation delivery systems, self-microemulsifying drug delivery systems, nanocrystals, hydrosol colloidal dispersions, microemulsions, solid dispersions, cosolvent use, dendrimers, polymer- drug conjugates, polymeric micelles, and mesoporous silica nanoparticles. For each approach the book discusses the main instrumentation, operation principles and theoretical background, with a focus on critical formulation features and clinical studies. Finally, the book includes some recent and novel applications, scale-up considerations and regulatory issues. Drug Delivery Strategies for Poorly Water-Soluble Drugs is an essential multidisciplinary guide to this important area of drug formulation for researchers in industry and academia working in drug delivery, polymers and biomaterials |
| Beschreibung: | Description based on publisher supplied metadata and other sources |
| Beschreibung: | 1 online resource (669 pages) |
| ISBN: | 9781118444672 9780470711972 |
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| 520 | |a Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to patients. Consequently, the development of techniques and materials to overcome these hurdles is a major area of research in pharmaceutical companies. Drug Delivery Strategies for Poorly Water-Soluble Drugs provides a comprehensive overview of currently used formulation strategies for hydrophobic drugs, including liposome formulation, cyclodextrin drug carriers, solid lipid nanoparticles, polymeric drug encapsulation delivery systems, self-microemulsifying drug delivery systems, nanocrystals, hydrosol colloidal dispersions, microemulsions, solid dispersions, cosolvent use, dendrimers, polymer- drug conjugates, polymeric micelles, and mesoporous silica nanoparticles. For each approach the book discusses the main instrumentation, operation principles and theoretical background, with a focus on critical formulation features and clinical studies. Finally, the book includes some recent and novel applications, scale-up considerations and regulatory issues. Drug Delivery Strategies for Poorly Water-Soluble Drugs is an essential multidisciplinary guide to this important area of drug formulation for researchers in industry and academia working in drug delivery, polymers and biomaterials | ||
| 650 | 4 | |a Chemistry, Pharmaceutical - methods | |
| 650 | 4 | |a Chemistry, Pharmaceutical -- Methods | |
| 650 | 4 | |a Drug Carriers - pharmacology | |
| 650 | 4 | |a Drug carriers -- Pharmacology | |
| 650 | 4 | |a Drug Delivery Systems | |
| 650 | 4 | |a Drug delivery systems | |
| 650 | 4 | |a Hydrophobic and Hydrophilic Interactions | |
| 650 | 4 | |a Solubility | |
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Datensatz im Suchindex
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| author | Douroumis, Dionysios |
| author_facet | Douroumis, Dionysios |
| author_role | aut |
| author_sort | Douroumis, Dionysios |
| author_variant | d d dd |
| building | Verbundindex |
| bvnumber | BV044049918 |
| collection | ZDB-30-PAD |
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| dewey-full | 615.19 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615.19 |
| dewey-search | 615.19 |
| dewey-sort | 3615.19 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| edition | 1st ed |
| format | Electronic eBook |
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| illustrated | Not Illustrated |
| indexdate | 2024-07-10T07:42:10Z |
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| isbn | 9781118444672 9780470711972 |
| language | English |
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| spelling | Douroumis, Dionysios Verfasser aut Drug Delivery Strategies for Poorly Water-Soluble Drugs 1st ed Somerset Wiley 2012 © 2013 1 online resource (669 pages) txt rdacontent c rdamedia cr rdacarrier Advances in Pharmaceutical Technology Description based on publisher supplied metadata and other sources Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to patients. Consequently, the development of techniques and materials to overcome these hurdles is a major area of research in pharmaceutical companies. Drug Delivery Strategies for Poorly Water-Soluble Drugs provides a comprehensive overview of currently used formulation strategies for hydrophobic drugs, including liposome formulation, cyclodextrin drug carriers, solid lipid nanoparticles, polymeric drug encapsulation delivery systems, self-microemulsifying drug delivery systems, nanocrystals, hydrosol colloidal dispersions, microemulsions, solid dispersions, cosolvent use, dendrimers, polymer- drug conjugates, polymeric micelles, and mesoporous silica nanoparticles. For each approach the book discusses the main instrumentation, operation principles and theoretical background, with a focus on critical formulation features and clinical studies. Finally, the book includes some recent and novel applications, scale-up considerations and regulatory issues. Drug Delivery Strategies for Poorly Water-Soluble Drugs is an essential multidisciplinary guide to this important area of drug formulation for researchers in industry and academia working in drug delivery, polymers and biomaterials Chemistry, Pharmaceutical - methods Chemistry, Pharmaceutical -- Methods Drug Carriers - pharmacology Drug carriers -- Pharmacology Drug Delivery Systems Drug delivery systems Hydrophobic and Hydrophilic Interactions Solubility Wirkstofffreisetzung (DE-588)4190018-2 gnd rswk-swf Löslichkeit (DE-588)4114435-1 gnd rswk-swf Arzneistoffträger (DE-588)4278196-6 gnd rswk-swf Arzneistoffträger (DE-588)4278196-6 s Wirkstofffreisetzung (DE-588)4190018-2 s Löslichkeit (DE-588)4114435-1 s 1\p DE-604 Erscheint auch als Druck-Ausgabe Douroumis, Dionysios Drug Delivery Strategies for Poorly Water-Soluble Drugs 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Douroumis, Dionysios Drug Delivery Strategies for Poorly Water-Soluble Drugs Chemistry, Pharmaceutical - methods Chemistry, Pharmaceutical -- Methods Drug Carriers - pharmacology Drug carriers -- Pharmacology Drug Delivery Systems Drug delivery systems Hydrophobic and Hydrophilic Interactions Solubility Wirkstofffreisetzung (DE-588)4190018-2 gnd Löslichkeit (DE-588)4114435-1 gnd Arzneistoffträger (DE-588)4278196-6 gnd |
| subject_GND | (DE-588)4190018-2 (DE-588)4114435-1 (DE-588)4278196-6 |
| title | Drug Delivery Strategies for Poorly Water-Soluble Drugs |
| title_auth | Drug Delivery Strategies for Poorly Water-Soluble Drugs |
| title_exact_search | Drug Delivery Strategies for Poorly Water-Soluble Drugs |
| title_full | Drug Delivery Strategies for Poorly Water-Soluble Drugs |
| title_fullStr | Drug Delivery Strategies for Poorly Water-Soluble Drugs |
| title_full_unstemmed | Drug Delivery Strategies for Poorly Water-Soluble Drugs |
| title_short | Drug Delivery Strategies for Poorly Water-Soluble Drugs |
| title_sort | drug delivery strategies for poorly water soluble drugs |
| topic | Chemistry, Pharmaceutical - methods Chemistry, Pharmaceutical -- Methods Drug Carriers - pharmacology Drug carriers -- Pharmacology Drug Delivery Systems Drug delivery systems Hydrophobic and Hydrophilic Interactions Solubility Wirkstofffreisetzung (DE-588)4190018-2 gnd Löslichkeit (DE-588)4114435-1 gnd Arzneistoffträger (DE-588)4278196-6 gnd |
| topic_facet | Chemistry, Pharmaceutical - methods Chemistry, Pharmaceutical -- Methods Drug Carriers - pharmacology Drug carriers -- Pharmacology Drug Delivery Systems Drug delivery systems Hydrophobic and Hydrophilic Interactions Solubility Wirkstofffreisetzung Löslichkeit Arzneistoffträger |
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